Results 211 to 220 of about 70,385 (287)

Case Report: Recurrent Guillain–Barré Syndrome in a 56‐Year‐Old Male

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Recurrent Guillain–Barré syndrome (GBS) is an uncommon variant of immune‐mediated polyradiculoneuropathy. We report a 56‐year‐old male who had two distinct episodes of acute inflammatory demyelinating neuropathy within the span of 3 months. The first episode presented with an episode of ascending paralysis and areflexia, with nerve conduction ...
Farah Sadiq   +8 more
wiley   +1 more source

MOG Antibody‐Associated Optic Neuritis Masquerading as Traumatic Optic Neuropathy Following Cranial Trauma: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) is an autoimmune disorder characterized by demyelination of the central nervous system. It can impact the optic nerves, spinal cord, brain parenchyma, and brainstem, resulting in various clinical presentations such as acute disseminated encephalomyelitis (ADEM), optic ...
Yuxian Shi   +5 more
wiley   +1 more source

Acute Disseminated Encephalomyelitis Presenting as Fever of Unknown Origin in a 4‐Year‐Old Boy: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT A 4‐year‐old boy presented with prolonged fever of unknown origin and systemic inflammation without early neurological signs. MRI revealed multifocal demyelination, and MOG antibodies were positive. He was diagnosed with ADEM and treated with steroids and IVIg, but relapsed twice, consistent with multiphasic disseminated encephalomyelitis ...
Pedro Pau
wiley   +1 more source

Optic Neuritis in the Puerperium Mimicking Severe Preeclampsia: A Neurological Differential Diagnosis in the Obstetric Emergency Setting

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Optic neuritis is an acute inflammatory disease that can cause acute visual loss. We present a case of a 22‐year‐old female in postpartum with acute headache, retroocular pain, and bilateral amaurosis. Orbit MRI revealed inflammatory changes in both neurovascular optical bundles.
Jose Luis Rojas‐Oviedo   +5 more
wiley   +1 more source

When Treatment Turns to Stone: Injection‐Site Calcinosis Associated With Interferon‐β in Multiple Sclerosis: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Injection‐site calcinosis is a rare complication of interferon‐β therapy in multiple sclerosis. We report a 52‐year‐old woman with stable bilateral gluteal calcifications after long‐term subcutaneous interferon‐β‐1b therapy. Findings were most consistent with probable dystrophic calcinosis cutis secondary to chronic repeated injection‐site ...
Anna Walter   +3 more
wiley   +1 more source

Spinal Cord Involvement in Neurosarcoidosis: A Case of Longitudinally Extensive Transverse Myelitis at Disease Onset

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Acute‐onset neurological deficits in otherwise healthy individuals warrant a broad differential diagnosis. Neurosarcoidosis presenting as longitudinally extensive transverse myelitis is rare, mimicking demyelinating, infectious, or neoplastic disorders. Early recognition, histopathological confirmation, and timely immunosuppressive therapy are
Areeb Tiwana   +2 more
wiley   +1 more source

A Case of Cerebral Cortical Encephalitis

open access: yes
Annals of Clinical and Translational Neurology, Volume 13, Issue 6, Page 1294-1296, June 2026.
Sixiao Liu, Kunqian Ji, Wei Wu, Wei Li
wiley   +1 more source

Neuromyelitis Optica Spectrum Disorder Following Pituitary Tumor Resection: A Rare but Critical Differential in Neurosurgical Practice

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Neuromyelitis optica spectrum disorder (NMOSD) is a rare, immune‐mediated astrocytopathy disorder that predominantly affects adults. Postoperative cases are scarcely reported. A 75‐year‐old woman underwent uncomplicated endoscopic resection of a nonfunctional pituitary macro‐adenoma.
Arad Iranmehr   +6 more
wiley   +1 more source

CYP46A1‐Targeted Treatment Alleviates Long‐Term White Matter Injury Following Traumatic Brain Injury by Promoting Cholesterol Metabolic Clearance and Remyelination

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Our findings demonstrate that CYP46A1 plays a critical role in regulating cholesterol homeostasis in microglia and that the targeting of CYP46A1 may offer a viable therapeutic approach for traumatic brain injury (TBI). The CYP46A1 activator Efavirenz reduces white matter damage by increasing the levels of the cholesterol metabolite 24OHC, thereby ...
Lin Li   +10 more
wiley   +1 more source

Exercise Intervention for REM Sleep Behavior Disorder in Parkinson's Disease: Mechanisms and Implications for Neurorehabilitation

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
This review systematically explores exercise as a multi‐target intervention for RBD, highlighting its mechanisms of action and regulatory effects on key pathophysiological processes. ABSTRACT Backgrounds REM sleep behavior disorder (RBD) is a prodromal non‐motor symptom of Parkinson's disease (PD) and other α‐synucleinopathies, affecting approximately ...
Xinhui Qiu   +4 more
wiley   +1 more source

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