Results 261 to 270 of about 9,225,670 (325)
Clinical Utility of Far‐Field Potentials in Amyotrophic Lateral Sclerosis
Muscle &Nerve, Volume 72, Issue 4, Page 616-624, October 2025.ABSTRACT Introduction/Aims Far field potentials (FFP) have been proposed as a reliable neurophysiological prognostic biomarker in amyotrophic lateral sclerosis (ALS). This study evaluates the diagnostic utility of ulnar nerve FFP in ALS. Methods Comprehensive peripheral neurophysiological assessments were conducted in 62 ALS and 43 ALS‐mimicking ...
Aicee Dawn Calma +7 more
wiley +1 more source
The Chemical Record, Volume 25, Issue 10, October 2025.This review explores aptamers as therapeutic oligonucleotides targeting neurodegenerative diseases, including Alzheimer's, Parkinson's, and Huntington's, with a focus on G‐quadruplex‐forming sequences. It discusses chemical modifications that enhance aptamer stability and function, alongside the use of clay nanoparticles, such as halloysite nanotubes ...
Valentina Arciuolo +9 more
wiley +1 more source
Microbiology and Immunology, Volume 69, Issue 10, Page 495-501, October 2025.ABSTRACT It is believed that human endogenous retrovirus (HERV)‐W plays a fundamental role in multiple sclerosis (MS) pathogenesis, probably by inducing humoral and cellular immunopathological response. HERVs present regions of similarity to myelin oligodendrocyte glycoprotein (MOG) and therefore could induce autoimmunity through the mechanism of ...
Karin C. Garcia +11 more
wiley +1 more source
Recurrent asymptomatic demyelinating disease following 13-cis-retinoic acid exposure
, 2009 Darin T. Okuda, Michael D. Prados
openalex +2 more sources
Synthetic microneurotrophins: Neurotrophin receptors for therapeutics of neurodegenerative diseases
British Journal of Pharmacology, Volume 182, Issue 19, Page 4466-4489, October 2025.Neurodegenerative disorders are characterised by the chronic progressive degeneration of specific neuronal subtypes, neuroinflammation, myelin damage and synaptic loss. Despite their growing incidence, advancements in effective treatments remain limited, because of lack of knowledge for the aetiology of the diverse pathophysiology to design systematic ...
Ioanna Zota +4 more
wiley +1 more source
Beyond synapses: cytoplasmic connections in brain function and evolution
Biological Reviews, Volume 100, Issue 5, Page 2055-2070, October 2025.ABSTRACT Following Ramón y Cajal's groundbreaking contributions to the identification of synapses, research in neuroscience predominantly focused on their pivotal role in neural communication (the neuron doctrine), overlooking an intriguing possibility suggested by Golgi of non‐synaptic interactions among neural cells.
Malalaniaina Rakotobe, Chiara Zurzolo
wiley +1 more source
Developmental Medicine &Child Neurology, Volume 67, Issue 10, Page 1340-1353, October 2025.The proposed conceptual framework highlighting parents' central role in their child's healthcare experience. This original article is commented by Kettle‐Frisby on pages 1247–1248 of this issue. Abstract Aim To explore parents' experiences of family‐centered care (FCC) in a pediatric neurology clinic. Method In this explanatory sequential mixed‐methods
Ege Sarikaya +21 more
wiley +1 more source
European Journal of Neurology, Volume 32, Issue 10, October 2025.Venn diagram representing the presence of conduction block defined by compound muscle action potential (CMAP) amplitude reduction by > 30% (CB‐amp > 30%), temporal dispersion of proximal CMAP versus distal CMAP by > 30% (TD), and F‐wave prolongation in demyelinating range, or F‐wave absence, in 47 subjects with multifocal motor neuropathy from ...
Yusuf A. Rajabally +6 more
wiley +1 more source