Results 271 to 280 of about 9,225,670 (325)

Optic neuritis due to demyelinating disease

Indian Journal of Ophthalmology, 1975
Sood G, Kapoor Shashi, Rao V, Krishnamurthy Gyanam, Ramakrishnan S, Rajisamy   +5 more
doaj  

Clinically Relevant Patterns of Co‐Fluctuating Structure and Function in Multiple Sclerosis

European Journal of Neurology, Volume 32, Issue 10, October 2025.
Multimodal component analysis identified co‐fluctuating regional patterns of lesions, structural disconnection, and hyperconnectivity in MS, providing superior explanations of clinical outcomes compared to traditional MRI metrics. ABSTRACT Background While structural and functional connectivity changes in multiple sclerosis (MS) are well documented ...
Jian Zhang, Marco Battaglini, Rosa Cortese, Maria Laura Stromillo, Marzia Mortilla, Ludovico Luchetti, Giordano Gentile, Emilio Portaccio, Maria Pia Amato, Menno M. Schoonheim, Nicola De Stefano   +10 more
wiley   +1 more source

Monoclonal Gammopathy in Amyotrophic Lateral Sclerosis: No Impact on Clinical Progression and Immunotherapy Outcomes

European Journal of Neurology, Volume 32, Issue 10, October 2025.
In a Korean amyotrophic lateral sclerosis cohort, monoclonal gammopathy prevalence was 1.0% (≥ 65 years 1.9% vs. < 65 years 0.7%); patients with amyotrophic lateral sclerosis (ALS) and monoclonal gammopathy were older and showed male predominance. In ALS, monoclonal gammopathy–targeted immunotherapy did not change ALSFRS‐R decline or survival, and ...
Hyunkee Kim, Ji‐Eun Uhm, Jinseok Park, Yong sung Kim, Wonjae Sung, Sanggon Lee, Seung Hyun Kim, Ki‐Wook Oh   +7 more
wiley   +1 more source

MS Fatigue Post High‐Efficacy Treatment

European Journal of Neurology, Volume 32, Issue 10, October 2025.
Fatigue affects up to 95% of people with multiple sclerosis (MS), yet its response to high‐efficacy treatments (HETs) remains unclear. This meta‐analysis of 18 studies found a small but significant reduction in fatigue, particularly physical fatigue, following continuous HETs.
C. Sales, R. Patel, T. Wijeratne, A. Bruestle, N. Cherbuin   +4 more
wiley   +1 more source

Flow Cytometric Assessment of TRBC1 Expression for the Diagnosis of T‐Cell Lymphoma: Clinical Utility and Pitfalls Related to T‐Cell Clones of Uncertain Significance

International Journal of Laboratory Hematology, Volume 47, Issue 5, Page 840-848, October 2025.
ABSTRACT Background T‐cell receptor constant beta chain 1 (TRBC1) has emerged as a potential clonal marker for T‐cell lymphoma. This study evaluated TRBC1 expression using flow cytometry in healthy individuals and various clinical specimens, assessing its clinical utility in the diagnosis of T‐cell lymphomas.
SooHo Yu, Boram Kim, Sang Eun Yoon, Hee‐Jin Kim, Hyun‐Young Kim   +4 more
wiley   +1 more source

Tyro3 deletion is protective in experimental autoimmune encephalomyelitis

Immunology &Cell Biology, Volume 103, Issue 9, Page 857-870, October 2025.
Multiple sclerosis pathogenesis involves the complex interplay between the peripheral immune response and the central nervous system. Gas6 is a promising therapy to promote remyelination; however, Gas6 and its receptors (the TAM receptor family) are widely expressed in both immune cells and the central nervous system. Our study demonstrates that global
Michele D Binder, Mohammad Asadian, Darnell Leepel, Gerry ZM Ma, Andrea Aprico, Liz Barreto‐Arce, Trevor J Kilpatrick, Sarrabeth Stone   +7 more
wiley   +1 more source

Quadriparesis after CD19 × CD22 bicistronic chimeric antigen receptor T cells for B‐cell acute lymphoblastic leukaemia

British Journal of Haematology, Volume 207, Issue 4, Page 1673-1678, October 2025.
Alexander W. Rankin, Sara K. Silbert, Brynn B. Duncan, Bonnie Yates, Avindra Nath, Nadia Biassou, Anthony F. Suffredini, Robert L. Danner, Charles Natanson, Amarpreet K. Ahluwalia, Lauren Little, Toni Foley, Hemant S. Murthy, Haneen Shalabi, Paul Nyquist, Nirali N. Shah   +15 more
wiley   +1 more source

Neurological manifestations of chronic graft versus host disease

Internal Medicine Journal, Volume 55, Issue 10, Page 1639-1646, October 2025.
Abstract Introduction Allogeneic haemopoietic stem cell transplant (allo‐HSCT) is an established therapy for many malignant and non‐malignant conditions, with an increasing number of uses and indications in recent decades. Complications including graft versus host disease (GvHD) carry significant morbidity and mortality.
Tal Koren, Alice Kwok, William Stevenson, Kate Ahmad, Joseph Nogajski, John Parratt, Ian Kerridge, Karl Ng   +7 more
wiley   +1 more source

Erectile dysfunction in dermatology and venereology: From aetiopathogenic mechanisms to practical considerations for dermato‐venereologists

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 10, Page 1725-1737, October 2025.
Multiple inflammatory, infectious and autoimmune dermato‐venereological conditions are associated with erectile dysfunction (ED) due to underlying intricate vasculogenic, neurogenic, endocrine and psychogenic mechanisms. It is recommended that practitioners screen dermatology patients for ED and associated comorbidities, provide personalized lifestyle ...
Andrei Tanasov, George‐Sorin Tiplica
wiley   +1 more source

Fundamental Neurochemistry Review: Sphingolipids and Ceramides in Brain Development

Journal of Neurochemistry, Volume 169, Issue 10, October 2025.
Ceramides and sphingolipids in brain development and cell compartments. Ceramides and sphingolipids are known to influence multiple steps of brain development, including the formation of the neural tube, neural stem cell polarity and proliferation at the ventricular boundary, neuronal migration—for example, whilst migrating on radial glial processes ...
Kaviya Chinnappa, Fiona Ballorin, Fiona Francis   +2 more
wiley   +1 more source