Results 21 to 30 of about 69,571 (229)

Demyelinating diseases [PDF]

open access: yesJournal of Clinical Pathology, 2006
A diagnosis of demyelination carries important therapeutic and prognostic implications. In most cases the diagnosis is made clinically, and involvement of the histopathologist is largely confined to postmortem confirmation and clinicopathological correlation.
openaire   +3 more sources

Magnetic Resonance Imaging and Clinical Features of the Demyelinating Degeneration of White Matter in Young Patients

open access: yesInternational Journal of General Medicine, 2021
Jian Li,1 Yi-Ming Zhao2 1Department of Neurology, Peking University Third Hospital, Beijing, 100191, People’s Republic of China; 2Center for Clinical Epidemiology, Peking University Third Hospital, Beijing, 100191, People’s Republic of ...
Li J, Zhao YM
doaj  

Effects of Keratinocyte-Derived Cytokine (CXCL-1) on the Development of Theiler's Virus-Induced Demyelinating Disease

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
CXCL-1, also called keratinocyte-derived cytokine (KC), is a predominant chemokine produced in glial cells upon infection with Theiler's murine encephalomyelitis virus (TMEV).
Min H. Kang, Young H. Jin, Byung S. Kim
doaj   +1 more source

Changes of statistical structural fluctuations unveils an early compacted degraded stage of PNS myelin [PDF]

open access: yesScientific Reports 4, 5430 (2014), 2013
Degradation of the myelin sheath is a common pathology underlying demyelinating neurological diseases from Multiple Sclerosis to Leukodistrophies. Although large malformations of myelin ultrastructure in the advanced stages of Wallerian degradation is known, its subtle structural variations at early stages of demyelination remains poorly characterized.
arxiv   +1 more source

Reactivity to Novel Autoantigens in Patients with Coexisting Central Nervous System Demyelinating Disease and Autoimmune Thyroid Disease

open access: yesFrontiers in Immunology, 2017
Several lines of evidence suggest a definite and unique link between CNS demyelinating diseases and autoimmune thyroid disease (AITD). The aim of the current study was to systematically compare the clinical and laboratory features of patients with ...
Judith M. Greer   +4 more
doaj   +1 more source

Defining distinct features of anti-MOG antibody associated central nervous system demyelination

open access: yesTherapeutic Advances in Neurological Disorders, 2018
Extensive research over the last decades basically failed to identify a common cause of noninfectious inflammatory central nervous system (CNS) demyelinating disease.
Martin S. Weber   +3 more
doaj   +1 more source

Utility of cerebrospinal fluid liquid biopsy in distinguishing CNS lymphoma from cerebrospinal infectious/demyelinating diseases

open access: yesCancer Medicine, 2023
Background Distinguishing between central nervous system lymphoma (CNSL) and CNS infectious and/or demyelinating diseases, although clinically important, is sometimes difficult even using imaging strategies and conventional cerebrospinal fluid (CSF ...
Chisako Iriyama   +18 more
doaj   +1 more source

MRI Images, Brain Lesions and Deep Learning [PDF]

open access: yesarXiv, 2021
Medical brain image analysis is a necessary step in Computer Assisted /Aided Diagnosis (CAD) systems. Advancements in both hardware and software in the past few years have led to improved segmentation and classification of various diseases. In the present work, we review the published literature on systems and algorithms that allow for classification ...
arxiv  

Prostaglandin E2 produced following infection with Theiler's virus promotes the pathogenesis of demyelinating disease. [PDF]

open access: yesPLoS ONE, 2017
Infection of various cells with Theiler's murine encephalomyelitis virus (TMEV) activates the TLR- and melanoma differentiation-associated gene 5 (MDA5)-dependent pathways, resulting in the production of IL-1β via the activation of caspase-1 upon ...
Seung Jae Kim   +2 more
doaj   +1 more source

Fulminant Demyelinating Diseases [PDF]

open access: yesThe Neurohospitalist, 2013
Fulminant demyelinating disease is a heading that covers acute disseminated encephalomyelitis and its variant acute hemorrhagic leukoencephalitis (Hurst disease), severe relapses of multiple sclerosis (MS), variants of MS (tumefactive MS, Marburg variant, Balo concentric sclerosis, myelinoclastic diffuse sclerosis), and neuromyelitis optica-spectrum ...
Orhun H. Kantarci, Megan R. Rahmlow
openaire   +3 more sources

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