Results 31 to 40 of about 69,571 (229)

Glutamate Receptors in Neuroinflammatory Demyelinating Disease

open access: yesMediators of Inflammation, 2006
Multiple sclerosis (MS) is a chronic demyelinating disease of the human central nervous system (CNS). The condition predominantly affects young adults and is characterised by immunological and inflammatory changes in the periphery and CNS that contribute
Christopher Bolton, Carolyn Paul
doaj   +2 more sources

Research Progress on the Animal Models of Neuromyelitis Optica Spectrum Disorders-related Neuropathic Pain

open access: yesXiehe Yixue Zazhi, 2023
Neuromyelitis optica spectrum disorders(NMOSD), an inflammatory demyelinating disease of central nervous system, is characterized by optic neuritis, longitudinally extensive transverse myelitis, and neuropathic pain.
SONG Shujia   +4 more
doaj   +1 more source

Learning Myelin Content in Multiple Sclerosis from Multimodal MRI through Adversarial Training [PDF]

open access: yes, 2018
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS). A reliable measure of the tissue myelin content is therefore essential for the understanding of the physiopathology of MS, tracking progression and assessing treatment efficacy.
arxiv   +1 more source

Anaesthesia and demyelinating disease [PDF]

open access: yesAnaesthesia, 1980
SummaryThe demyelinating diseases are classified and the current concepts of the aetiology and pathophysiology of the most common of these diseases, multiple sclerosis, are described. The effects of the impaired function, local responses and known complications of the disease on the choice of anaesthetic, drugs and techniques are discussed.
T. E. J. Healy, Ronald M. Jones
openaire   +3 more sources

Asymmetric Type F Botulism with Cranial Nerve Demyelination

open access: yesEmerging Infectious Diseases, 2012
We report a case of type F botulism in a patient with bilateral but asymmetric neurologic deficits. Cranial nerve demyelination was found during autopsy. Bilateral, asymmetric clinical signs, although rare, do not rule out botulism.
Alina Filozov   +6 more
doaj   +1 more source

The first case report of Haim Munk disease with neurological manifestations and literature review

open access: yesClinical Case Reports, 2021
HMS can have neurologic MS like manifestations. It is urgent to do more research and report probable unknown associations of HMS for its better management.
Mehdi Moghaddasi   +5 more
doaj   +1 more source

Detection of MOG-IgG in Clinical Samples by Live Cell-Based Assays: Performance of Immunofluorescence Microscopy and Flow Cytometry

open access: yesFrontiers in Immunology, 2021
Human antibodies against Myelin Oligodendrocyte Glycoprotein (MOG) from immunoglobulin-G subclasses (MOG-IgG) have been recently associated with a new subgroup of neurological autoimmune diseases with distinct clinical characteristics from multiple ...
Amanda Marchionatti   +5 more
doaj   +1 more source

Unsupervised brain lesion segmentation from MRI using a convolutional autoencoder [PDF]

open access: yes, 2018
Lesions that appear hyperintense in both Fluid Attenuated Inversion Recovery (FLAIR) and T2-weighted magnetic resonance images (MRIs) of the human brain are common in the brains of the elderly population and may be caused by ischemia or demyelination. Lesions are biomarkers for various neurodegenerative diseases, making accurate quantification of them ...
arxiv   +1 more source

Unsupervised Brain Anomaly Detection and Segmentation with Transformers [PDF]

open access: yesarXiv, 2021
Pathological brain appearances may be so heterogeneous as to be intelligible only as anomalies, defined by their deviation from normality rather than any specific pathological characteristic. Amongst the hardest tasks in medical imaging, detecting such anomalies requires models of the normal brain that combine compactness with the expressivity of the ...
arxiv  

Bayesian Lesion Estimation with a Structured Spike-and-Slab Prior [PDF]

open access: yesarXiv, 2022
Neural demyelination and brain damage accumulated in white matter appear as hyperintense areas on T2-weighted MRI scans in the form of lesions. Modeling binary images at the population level, where each voxel represents the existence of a lesion, plays an important role in understanding aging and inflammatory diseases.
arxiv  

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