Results 81 to 90 of about 9,016,736 (303)
Brain Pathology, Volume 33, Issue 1, January 2023., 2023 Nogo‐A oligodendrocytes expression emerges at perilesional regions over time and suggests an extended therapeutical window for anti‐Nogo‐A pathway trageting interventrions beyond four weeks in patients after spinal cord injury. Abstract The myelin‐associated inhibitor Nogo‐A (Reticulon 4, RTN4) restricts axonal outgrowth, plasticity, and neural ...
Carmen Schwaiger +9 more
wiley +1 more source
Вопросы современной педиатрии, 2009 Inflammatory demyelinating diseases in children and adolescents are sufficient problem of modern medicine. Its topicality is conditioned by as traditionally high prevalence of acute demyelinating conditions (acute disseminated encephalomyelitis) as ...
O.V. Bykova +5 more
doaj +2 more sources
Frontiers in Immunology, 2018 Inflammatory demyelinating CNS syndromes include, besides their most common entity multiple sclerosis (MS), several different diseases of either monophasic or recurrent character—including neuromyelitis optica spectrum disorders (NMOSDs) and acute ...
Franziska Di Pauli, Thomas Berger
doaj +1 more source
High Fat Low Carbohydrate Diet Is Linked to CNS Autoimmunity Protection
Advanced Science, EarlyView.Mapping global epidemiological data to macronutrient supply reveals high carbohydrate, in contrast to high fat supply, associates with increased multiple sclerosis (MS) prevalence and incidence. This is confirmed in a mouse MS model, experimental autoimmune encephalomyelitis (EAE), using isocaloric diets: a high carbohydrate diet aggravates, a high ...
Duan Ni +15 more
wiley +1 more source
Mechanisms of remyelination: recent insight from experimental models
Biomolecular Concepts, 2014 Oligodendrocytes and myelin play essential roles in the vertebrate central nervous system. Demyelination disrupts saltatory nerve conduction, leading to axonal degeneration and neurological disabilities.
Tanaka Tatsuhide, Yoshida Shigetaka
doaj +1 more source
Self-supervised Lesion Change Detection and Localisation in Longitudinal Multiple Sclerosis Brain Imaging [PDF]
arXiv, 2021 Longitudinal imaging forms an essential component in the management and follow-up of many medical conditions. The presence of lesion changes on serial imaging can have significant impact on clinical decision making, highlighting the important role for automated change detection.
arxiv
Advanced Science, EarlyView.In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han +10 more
wiley +1 more source
Computational Reproducibility in Metabolite Quantification Applied to Short Echo Time in Vivo MR Spectroscopy [PDF]
IEEE International Symposium on Biomedical Imaging, Apr 2023,
Cartagena de Indias, France, 2023 In vivo metabolite quantification by short echo time MR spectroscopy is a challenge for which various methods have been proposed. In this study, the reproducibility of quantification outcomes is questioned at three distinct levels: (i) between-software (LCModel and cQUEST), (ii) withinsoftware (with different parameter sets), and (iii) across software ...
arxiv
Biomedical Applications of Gadolinium‐Containing Biomaterials: Not Only MRI Contrast Agent
Advanced Science, EarlyView.This paper summarizes the latest applications and potential mechanisms of the rare earth element gadolinium in biomedical fields, in addition to its traditional application as an MRI contrast agent, including osteogenesis, antimicrobial, antitumor, bioimaging, bioprobes, and so on.
Xingtong Pan +9 more
wiley +1 more source
Forecasting Disease Burden In Philippines: A Symbolic Regression Analysis [PDF]
arXiv, 2021 Burden of disease measures the impact of living with illness and injury and dying prematurely and it is increasing worldwide leading cause of death both global and national. This paper aimed to propose an index of diseases and evaluate a mathematical model to describe the number of burden of disease by cause in the Philippines from 1990 - 2016. Through
arxiv