Results 251 to 260 of about 117,570 (300)
Some of the next articles are maybe not open access.
Current Opinion in Neurology, 2003
To review recent advances in heritable demyelinating neuropathies and their genotype-phenotype correlations.Two themes dominated the literature on demyelinating neuropathies in the past 2 years: (1) the dissection of the localization and roles of new molecules in the axon-Schwann cell unit, including periaxin and connexin32, which are mutated in ...
Lan, Zhou, John W, Griffin
openaire +2 more sources
To review recent advances in heritable demyelinating neuropathies and their genotype-phenotype correlations.Two themes dominated the literature on demyelinating neuropathies in the past 2 years: (1) the dissection of the localization and roles of new molecules in the axon-Schwann cell unit, including periaxin and connexin32, which are mutated in ...
Lan, Zhou, John W, Griffin
openaire +2 more sources
Continuum, 2016
This review summarizes a general approach to pediatric demyelination as well as specific features of each of the acquired demyelinating syndromes to help clinicians in their evaluation of children with these disorders. Case studies are included to illustrate the expanding phenotype of many of these syndromes.With the creation of consensus definitions ...
Sona, Narula, Brenda, Banwell
openaire +2 more sources
This review summarizes a general approach to pediatric demyelination as well as specific features of each of the acquired demyelinating syndromes to help clinicians in their evaluation of children with these disorders. Case studies are included to illustrate the expanding phenotype of many of these syndromes.With the creation of consensus definitions ...
Sona, Narula, Brenda, Banwell
openaire +2 more sources
Nature Neuroscience, 2007
The loss of central nervous system myelin and the failure of remyelination by oligodendrocytes contribute to the functional impairment that characterizes diseases such as multiple sclerosis. Why myelin repair fails in multiple sclerosis is currently unclear; however, new understanding of the generation of oligodendrocytes and myelination during ...
Robert H, Miller, Sha, Mi
openaire +2 more sources
The loss of central nervous system myelin and the failure of remyelination by oligodendrocytes contribute to the functional impairment that characterizes diseases such as multiple sclerosis. Why myelin repair fails in multiple sclerosis is currently unclear; however, new understanding of the generation of oligodendrocytes and myelination during ...
Robert H, Miller, Sha, Mi
openaire +2 more sources
Neurological Research, 2006
White matter lesions representing ischemic demyelination have evolved in terms of our understanding of their pathogenesis and potential clinical significance. Low density lesions on CT brain scan, most commonly seen in the periventricular region, also frequently seen in the centrum semiovale, have been termed 'leukoaraiosis'.
openaire +2 more sources
White matter lesions representing ischemic demyelination have evolved in terms of our understanding of their pathogenesis and potential clinical significance. Low density lesions on CT brain scan, most commonly seen in the periventricular region, also frequently seen in the centrum semiovale, have been termed 'leukoaraiosis'.
openaire +2 more sources
Tumefactive demyelinating lesions
Neuroradiology, 1996We studied 21 cases of pathologically confirmed tumefactive demyelinating lesions and reviewed the spectrum of tumefactive demyelinating lesions in the literature. Radiological features and clinical data were reviewed to characterize the lesions as consistent with a known demyelinating disease, most notably multiple sclerosis.
A P, Dagher, J, Smirniotopoulos
openaire +2 more sources
Abstract This chapter describes various clues to the diagnosis of multiple sclerosis (MS) based on the history, physical examination and investigation. Red flags that should alert the clinician to an alternative diagnosis are listed. Disorders that may present like MS and lead to erroneous diagnosis are discussed.
Christopher H. Hawkes +2 more
openaire +1 more source
Christopher H. Hawkes +2 more
openaire +1 more source
Journal of Histochemistry & Cytochemistry, 1981
Our interest in proteolytic enzymes derives from our work on the pathogenesis of multiple sclerosis (MS). In this disease of the central nervous system the myelin sheaths enveloping the axons disintegrate, usually in a patchy manner beginning around small veins or near the ventricles, resulting in lesions or “plaques.” The cause of MS is still unknown.
openaire +2 more sources
Our interest in proteolytic enzymes derives from our work on the pathogenesis of multiple sclerosis (MS). In this disease of the central nervous system the myelin sheaths enveloping the axons disintegrate, usually in a patchy manner beginning around small veins or near the ventricles, resulting in lesions or “plaques.” The cause of MS is still unknown.
openaire +2 more sources
[Demyelinating elements of demyelinated encephalopathy].
Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1992The myelin basic protein (MBPi) accounts for the main encephalitogenic antigen of the demyelinating encephalopathy, but other myelin elements also be noted by some articles. We tried to determine the relationship between W1 protein and the demyelinating encephalopathies. The 2',3'-cyclic nucleotide 3'-phospho-diesterase(CNPase, a gift from Dr.
openaire +1 more source
Demyelinating Diseases: Acute Demyelinating Encephalomyelitis (ADEM)
2019Acute demyelinating encephalomyelitis (ADEM) is clinically characterized by fever, headache, impaired conscious level, meningism, seizures, and progressive neurological signs.
Serge Weis +6 more
openaire +1 more source