Results 21 to 30 of about 540,123 (302)

Protein Denaturation Through the Use of Magnetic Molecularly Imprinted Polymer Nanoparticles

open access: yesMolecules, 2021
The inhibition of the protein function for therapeutic applications remains challenging despite progress these past years. While the targeting application of molecularly imprinted polymer are in their infancy, no use was ever made of their magnetic ...
Charlotte Boitard   +3 more
doaj   +1 more source

Factors Influencing the Prediction Accuracy of Model Peptides in Reversed-Phase Liquid Chromatography

open access: yesSeparations, 2023
Hydrophobicity is an important physicochemical property of peptides in solution. As well as being strongly associated with peptide stability and aggregation, hydrophobicity governs the solution based chromatographic separation processes, specifically ...
Othman Al Musaimi   +2 more
doaj   +1 more source

Appraisal of anti-arthritic and nephroprotective potential of Cuscuta reflexa

open access: yesPharmaceutical Biology, 2017
Context: Cuscuta reflexa Roxb. (Cuscutaceae) has been used traditionally for treating sore knees and kidney problems, but its efficacy has not been scientifically examined in treating arthritis and nephrotoxicity.
Alamgeer   +4 more
doaj   +1 more source

Ionic strength and buffering capacity of emulsifying salts determine denaturation and gelation temperatures of whey proteins

open access: yesJournal of Dairy Science, 2022
: Ionic conditions affect the denaturation and gelling of whey proteins, affecting the physical properties of foods in which proteins are used as ingredients.
D. Perez, F. Harte, T. Lopez-Pedemonte
doaj   +1 more source

Bubbles and denaturation in DNA [PDF]

open access: yes, 2006
The local opening of DNA is an intriguing phenomenon from a statistical physics point of view, but is also essential for its biological function. For instance, the transcription and replication of our genetic code can not take place without the unwinding
Altan-Bonnet   +47 more
core   +3 more sources

Denaturation: An Example of a Catastrophe [PDF]

open access: yesProceedings of the National Academy of Sciences, 1974
We show that a “phase diagram” for the conformational states of proteins can be constructed using the mathematical theory of singularities of functions developed recently by René Thom. For proteins subjected to the disruptive influences of temperature and/or concentration of denaturing agent, this theory can be used as a predictive tool to account for ...
Kozak, John J., Benham, Craig J.
openaire   +3 more sources

Measurement of substrate thermal resistance using DNA denaturation temperature [PDF]

open access: yes, 2009
Heat Transfer and Thermal Management have become important aspects of the developing field of uTAS systems particularly in the application of the the uTAS philosophy to thermally driven analysis techniques such as PCR.
Dalton, Tara   +2 more
core   +1 more source

Diameter Dependent Melting and Softening of dsDNA Under Cylindrical Confinement

open access: yesFrontiers in Chemistry, 2022
Carbon nanotubes (CNTs) are considered promising candidates for biomolecular confinement, including DNA encapsulation for gene delivery. Threshold values of diameters have been reported for double-stranded DNA (dsDNA) encapsulation inside CNTs.
Khadka B. Chhetri   +3 more
doaj   +1 more source

Reversible denaturation of oligomeric human chaperonin 10: Denatured state depends on chemical denaturant [PDF]

open access: yesProtein Science, 2000
AbstractChaperonins cpn60/cpn10 (GroEL/GroES in Escherichia coli) assist folding of nonnative polypeptides. Folding of the chaperonins themselves is distinct in that it entails assembly of a sevenfold symmetrical structure. We have characterized denaturation and renaturation of the recombinant human chaperonin 10 (cpn10), which forms a heptamer ...
J J, Guidry   +4 more
openaire   +2 more sources

Single molecule study of the DNA denaturation phase transition in the force-torsion space

open access: yes, 2012
We use the "magnetic tweezers" technique to reveal the structural transitions that DNA undergoes in the force-torsion space. In particular, we focus on regions corresponding to negative supercoiling. These regions are characterized by the formation of so-
Brogioli, D.   +6 more
core   +1 more source

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