Results 11 to 20 of about 2,203,280 (253)

DISORDER AND DENATURATION TRANSITION IN THE GENERALIZED POLAND-SCHERAGA MODEL [PDF]

open access: yes, 2020
36 pages, 3 figuresInternational audienceWe investigate the generalized Poland-Scheraga model, which is used in the bio-physical literature to model the DNA denaturation transition, in the case where the two strands are allowed to be non-complementary ...
Quentin Berger   +5 more
core   +3 more sources

Single-molecule chemical denaturation of riboswitches [PDF]

open access: yes, 2013
To date, single-molecule RNA science has been developed almost exclusively around the effect of metal ions as folding promoters and stabilizers of the RNA structure.
St-Pierre, Patrick   +14 more
core   +1 more source

Enzyme activity below the dynamical transition at 220K [PDF]

open access: yes, 1998
Enzyme activity requires the activation of anharmonic motions, such as jumps between potential energy wells. However, in general, the forms and time scales of the functionally important anharmonic dynamics coupled to motion along the reaction coordinate ...
Smith, Jeremy C.   +12 more
core   +1 more source

The molecular basis of the effect of temperature on enzyme activity [PDF]

open access: yes, 2010
Experimental data show that the effect of temperature on enzymes cannot be adequately explained in terms of a two-state model based on increases in activity and denaturation.
Oudshoorn, Matthew Leslie   +17 more
core   +1 more source

Honey-Induced Protein Stabilization as Studied by Fluorescein Isothiocyanate Fluorescence

open access: yesThe Scientific World Journal, 2013
Protein stabilizing potential of honey was studied on a model protein, bovine serum albumin (BSA), using extrinsic fluorescence of fluorescein isothiocyanate (FITC) as the probe.
Yin How Wong   +2 more
doaj   +1 more source

Modulation of the Structure and Stability of Novel Camel Lens Alpha-Crystallin by pH and Thermal Stress

open access: yesGels, 2022
Alpha-crystallin protein performs structural and chaperone functions in the lens and comprises alphaA and alphaB subunits at a molar ratio of 3:1. The highly complex alpha-crystallin structure challenges structural biologists because of its large dynamic
Ajamaluddin Malik   +3 more
doaj   +1 more source

Free cysteine modulates the conformation of human C/EBP homologous protein. [PDF]

open access: yesPLoS ONE, 2012
The C/EBP Homologous Protein (CHOP) is a nuclear protein that is integral to the unfolded protein response culminating from endoplasmic reticulum stress.
Vinay K Singh   +5 more
doaj   +1 more source

Calorimetric and spectroscopic investigation of the unfolding of human apolipoprotein B.

open access: yesJournal of Lipid Research, 1990
The unfolding of human apolipoprotein B-100 in its native lipid environment, low density lipoprotein (LDL), and in a soluble, lipid-free complex with sodium deoxycholate (NaDC) has been examined using differential scanning calorimetry (DSC) and near UV ...
MT Walsh, D Atkinson
doaj   +1 more source

Cryoprotective effect of trehalose and maltose on washed and frozen stored beef meat

open access: yesCzech Journal of Food Sciences, 2011
The cryoprotective effects of trehalose and maltose (w = 2-10%) on washed beef meat were investigated. Washed beef meat produced from fresh beef meat was frozen and stored for 360 days at -30°C.
Dragan Kovačević   +1 more
doaj   +1 more source

Calorimetric Study of Helix aspersa Maxima Hemocyanin Isoforms

open access: yesJournal of Analytical Methods in Chemistry, 2018
The thermal unfolding of hemocyanin isoforms, β-HaH and αD+N-HaH, isolated from the hemolymph of garden snails Helix aspersa maxima, was studied by means of differential scanning calorimetry (DSC). One transition, with an apparent transition temperature (
Svetla Todinova   +2 more
doaj   +1 more source

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