Results 181 to 190 of about 54,440 (362)

Tau‐targeting nanoparticles for treatment of Alzheimer's disease

Exploration, EarlyView.
Through review of comprehensive literature and research studies, it is found that tau‐targeting nanoparticles may posit beneficial applications to AD therapy. By targeting a key molecular mechanism known to propagate AD pathogenesis, tau‐targeting nanoparticles have the potential to facilitate tau tangle clearance, promote synaptic integrity, and ...
Shreya Pawar, Mohd Ahmar Rauf, Hosam Abdelhady, Arun K. Iyer   +3 more
wiley   +1 more source

Phosphino Carboxylic Acid Ester Functionalized Carbosilane Dendrimers: Nanoscale Ligands for the Pd-Catalyzed Hydrovinylation Reaction in a Membrane Reactor [PDF]

, 2000
Eva B. Eggeling, Neldes J. Hovestad, Johann T. B. H. Jastrzebski, Dieter Vogt, Gerard van Koten   +4 more
openalex   +1 more source

Drug delivery pathways to the central nervous system via the brain glymphatic system circumventing the blood‐brain barrier

Exploration, EarlyView.
The discovery of the glymphatic system has opened up a pathway for drug delivery to the brain by circumventing the blood‐brain barrier, which can effectively improve drug utilization. The methods of drug delivery through the glymphatic system include intrathecal injection, intranasal injection, and delivery through the meningeal lymphatic vessels.
Xiang Wang, Yue Yin, Huaijuan Zhou, Bowen Chi, Ling Guan, Pei Li, Jinhua Li, Yilong Wang   +7 more
wiley   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

Polycationic (Mixed) Core-Shell Dendrimers for Binding and Delivery of Inorganic/Organic Substrates [PDF]

, 2001
Arjan W. Kleij, Rob van de Coevering, Robertus J. M. Klein Gebbink, Anne-Marie Noordman, Anthony L. Spek, Gerard van Koten   +5 more
openalex   +2 more sources

Investigation of Electrode Systems Modified with Cobaltporphyrins Having Dendrimer Side-chains as Oxygen Sensors.

, 1997
Makoto Yuasa, Amane HOSHI, Isao Sekine
openalex   +2 more sources

Molecular modelling of dendrimers for nanoscale applications [PDF]

, 2000
Tahir Çağın, Guofeng Wang, Ryan Martin, Nicholas F. Breen, William A. Goddard   +4 more
openalex   +1 more source

Anisotropic assembly and fluorescence enhancement of conjugated polymer nanostructures

VIEW, Volume 3, Issue 6, December 2022., 2022
Graphical Abstract A facile, one‐step self‐assembly is achieved for forming conjugated polymers into anisotropic nanostructures such as ellipsoids, triangle‐rings, and nanowires. The nanostructures exhibit shape‐dependent absorption and fluorescence enhancement.
Xiaoju Men, Xiaofeng Fang, Zhihe Liu, Zhe Zhang, Changfeng Wu, Haobin Chen   +5 more
wiley   +1 more source

Silver Nanoparticle‐Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review

Global Challenges, EarlyView.
Silver nanoparticles (AgNPs) exhibit broad‐spectrum antiviral activity by targeting key viral structures and processes. They disrupt viral envelopes, compromising integrity, and bind to nucleocapsids, impairing viral replication. AgNPs also inhibit glycoprotein interactions, preventing viral attachment and entry into host cells.
Ekaterine Mosidze, Gianluigi Franci, Federica Dell'Annunziata, Nicoletta Capuano, Marica Colella, Flora Salzano, Massimiliano Galdiero, Aliosha Bakuridze, Veronica Folliero   +8 more
wiley   +1 more source

Veterinary nanomedicine: Pros and cons

Veterinary Medicine and Science, Volume 9, Issue 1, Page 494-506, January 2023., 2023
Abstract In recent years, nanotechnology has improved life with continuous growth in different fields. Nanoparticles can be employed in industry, imaging, engineering, and various biomedical filed because of their special physicochemical properties like rapid, effective, highly specific solutions, higher stability, biodegradability, biocompatibility ...
Fariba Jafary, Shima Motamedi, Isaac Karimi   +2 more
wiley   +1 more source