Results 31 to 40 of about 23,240 (264)

Supra and subgingival application of antiseptics or antibiotics during periodontal therapy

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero, Jorge Serrano, Nicole Birgit Arweiler, Thorsten Mathias Auschill, Ali Gürkan, Gülnur Emingil   +5 more
wiley   +1 more source

Dendrimer-mediated permeation enhancement of chlorhexidine digluconate: Determination of in vitro skin permeability and visualisation of dermal distribution

, 2021
Chlorhexidine digluconate (CHG) is a cationic bisbiguanide used in the UK as the first-line skin antiseptic prior to surgery in the UK due to its favourable efficacy and safety profile, high affinity for skin binding and minimal reports of resistance ...
Scurr, David J., Sabri, Akmal B., Moss, Gary P., Kirkby, Melissa   +3 more
core   +1 more source

Biodistribution and Biosafety of a Poly(Phosphorhydrazone) Dendrimer, an Anti-Inflammatory Drug-Candidate

Biomolecules, 2019
Dendrimers are nanosized, arborescent polymers of which size and structure are perfectly controlled. This is one reason why they are widely used for biomedical purposes.
Séverine Fruchon, Elisabeth Bellard, Nicolas Beton, Cécile Goursat, Abdelouahd Oukhrib, Anne-Marie Caminade, Muriel Blanzat, Cédric-Olivier Turrin, Muriel Golzio, Rémy Poupot   +9 more
doaj   +1 more source

Pull‐and‐Push Nanotherapeutic Hydrogels: Scavenging Inflammatory Triggers While Driving Tissue Regeneration in Burn Wounds

Advanced Functional Materials, EarlyView.
A nanounit‐assembled hydrogel employing a “pull‐and‐push” strategy simultaneously scavenges pro‐inflammatory cell‐free DNA (cfDNA) and delivers regenerative therapeutics in response to burn‐induced hyperthermia. By repolarizing macrophages and promoting angiogenesis, this multifunctional platform accelerates burn wound healing, offering a blueprint for
Han‐Sem Kim, Seong‐Jin Shin, Sak Lee, Nandin Mandakhbayar, Ji‐Hye Kang, Da‐Young Kong, Seong‐Doo Hong, Ueon Sang Shin, Hae‐Won Kim, Jung‐Hwan Lee   +9 more
wiley   +1 more source

Dendrimer-Mediated Immobilization of Catalytic Nanoparticles on Flat, Solid Supports

, 2016
Sixth-generation poly(amidoamine) (PAMAM) dendrimers have been used to explore methods for immobilizing Pd nanoparticles on atomically flat surfaces. Two methods are investigated.
Li Sun (4624), Richard M. Crooks (1346970)   +1 more
core   +1 more source

Development of Sub‐50 nm Core–Shell Silica Nanoparticles With Controlled In Vivo Behavior for 19F Magnetic Resonance Imaging

Angewandte Chemie, EarlyView.
Ultrasmall PFCE‐loaded silica nanoparticles synthesized through a one‐pot double‐emulsion synthesis method, where rapid silica shell formation kinetically fixes droplet size. The resulting s‐FLAME nanoparticles enable strong 19F MRI signals with enhanced hepatic clearance rate and tumor‐accumulation performance. ABSTRACT 19F magnetic resonance imaging (
Yue Wu, Masafumi Minoshima, Kazuya Kikuchi   +2 more
wiley   +2 more sources

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Dendrimer-Supported Oligothiophene Synthesis:  Aliphatic Ether Dendrimers in the Preparation of Oligothiophenes with Minimal Substitution

, 2016
Dendrimer-Supported Oligothiophene Synthesis:  Aliphatic Ether Dendrimers in the Preparation of Oligothiophenes with Minimal ...
Jean M. J. Fréchet (2443018), Manikandan Jayaraman (2956884), Patrick R. L. Malenfant (2663641)   +2 more
core   +1 more source

Dendrimer-Peptide Conjugates for Effective Blockade of the Interactions between SARS-CoV‑2 Spike Protein and Human ACE2 Receptor

, 2022
The coronavirus disease 2019 (COVID-19) pandemic has threatened the stability of global healthcare, which is becoming an endemic issue. Despite the development of various treatment strategies to fight COVID-19, the currently available treatment options ...
Seungpyo Hong (182769), Hanbit Kang (14298410), Petr Král, Seungpyo Hong, Woo-jin Jeong (1718116), Jiyoon Bu (7868327), Jianxin Wang (35827), Jianxin Wang, Heejoo Hong (14298413), Petr Král (1294236), Yanxiao Han, Hanbit Kang, Jiyoon Bu, Piper A Rawding, Heejoo Hong, Philip Mickel (14298404), Philip Mickel, Yanxiao Han (4269250), Piper A Rawding (14298407), Woo-jin Jeong   +19 more
core   +1 more source

Fructose‐Based Single‐Chain Polymer Nanoparticles for GLUT1–Mediated Delivery: Impact of Polymer Design on Uptake and In Vivo Performance

Advanced Healthcare Materials, EarlyView.
Single‐chain nanoparticles have been proposed as drug delivery carriers, but adding a tail can significantly enhance their performance. This was demonstrated using a tadpole‐like structure comprising a head prepared from a UV‐crosslinked fructose‐based glycopolymer capable of targeting GLUT receptors, combined with a PEG‐based tail. Compared with other
Hoang Yen Vo, Linqing Tian, Qiaoyun Wang, Evelyn Szabo, Rebecca Y. Lai, Fariba Dehghani, Martina H. Stenzel   +6 more
wiley   +1 more source