Results 11 to 20 of about 42,261 (248)

Dendrimer-protein interactions versus dendrimer-based nanomedicine [PDF]

Colloids and Surfaces B: Biointerfaces, 2017
Dendrimers are hyperbranched polymers belonging to the huge class of nanomedical devices. Their wide application in biology and medicine requires understanding of the fundamental mechanisms of their interactions with biological systems. Summarizing, electrostatic force plays the predominant role in dendrimer-protein interactions, especially with ...
Shcharbin, Dzmitry, Shcharbina, Natallia, Dzmitruk, Volha, Pedziwiatr-Werbicka, Elzbieta, Ionov, Maksim, Mignani, Serge, de la Mata, F. Javier, Gómez, Rafael, Muñoz-Fernández, Maria Angeles, Majoral, Jean-Pierre, Bryszewska, Maria   +10 more
openaire   +3 more sources

Structure of poly(propyl ether imine) (PETIM) dendrimer from fully atomistic molecular Dynamics Simulation and by Small Angle X-ray scattering [PDF]

, 2006
We study the structure of carboxylic acid terminated neutral poly (propyl ether imine) (PETIM) dendrimer from generation 1 through 6 (G1-G6) in a good solvent (water) by fully atomistic molecular dynamics (MD) simulations.
A. K. Sood, Adronov A., Chandan Jana, G. Jayamurugan, Hearshaw M. A., N. Jayaraman, Prabal K. Maiti, Rajesh Ganapathy, Rapaport D. C.   +8 more
core   +2 more sources

Molecular Dynamics Study of Charged Dendrimers in Salt-Free Solution: Effect of Counterions [PDF]

, 2005
Polyamidoamine (PAMAM) dendrimers, being protonated under physiological conditions, represent a promising class of nonviral, nano-sized vectors for drug and gene delivery. We performed extensive molecular dynamics simulations of a generic model dendrimer
Andrey A. Gurtovenko, Galperin D. E., Ilpo Vattulainen, Mikko Karttunen, Sergey V. Lyulin   +4 more
core   +3 more sources

Cytotoxicity of Dendrimers [PDF]

Biomolecules, 2019
Drug delivery systems are molecular platforms in which an active compound is packed into or loaded on a biocompatible nanoparticle. Such a solution improves the activity of the applied drug or decreases its side effects. Dendrimers are promising molecular platforms for drug delivery due to their unique properties.
Anna Janaszewska, Joanna Lazniewska, Przemysław Trzepiński, Monika Marcinkowska, Barbara Klajnert-Maculewicz   +4 more
openaire   +4 more sources

Partially glycosylated dendrimers block MD-2 and prevent TLR4-MD-2-LPS complex mediated cytokine responses. [PDF]

PLoS Computational Biology, 2011
The crystal structure of the TLR4-MD-2-LPS complex responsible for triggering powerful pro-inflammatory cytokine responses has recently become available. Central to cell surface complex formation is binding of lipopolysaccharide (LPS) to soluble MD-2. We
Teresa S Barata, Ian Teo, Steve Brocchini, Mire Zloh, Sunil Shaunak   +4 more
doaj   +1 more source

Review Dendrimer : Definisi, Sintesis, Aplikasi Dan Prospektif

Jurnal Kimia dan Kemasan, 2013
Dendrimer merupakan makrostruktur monodisperse dengan banyak cabang yang homogen dan degree of branching (DB) 100%. Dua cara sintesis dendrimer yaitu convergent dan divergent dilakukan.
Dwinna Rahmi
doaj   +1 more source

Investigations of excitation energy transfer and intramolecular interactions in a nitrogen corded distrylbenzene dendrimer system. [PDF]

, 2002
The photophysics of an amino-styrylbenzene dendrimer (A-DSB) system is probed by time-resolved and steady state luminescence spectroscopy. For two different generations of this dendrimer, steady state absorption, emission, and photoluminescence ...
Becky Letchford, Clare Mackie, Conti-Ramsden, G., Coopersmith, S., Coopersmith, S., Dockrell, J., Dockrell, J., Geoff Lindsay, Harter, S., Harter, S., Harter, S., Julie Dockrell, McGuire, S., Piers, E. V., Wylie, R. C., Wylie, R. C.   +15 more
core   +4 more sources

Turn-on Type Chemical Sensing of Vitamin K4 by Fluorene Dendrimers with Naphthalene Segments

Molecules, 2014
G1 and G2 fluorene dendrimers with naphthalene termini were synthesized as a fluorescence turn-on type chemical sensor for vitamin K4. The fluorene dendrimers were prepared by Williamson ether reaction between the fluorene core with dihydroxy groups and ...
Naoya Adachi, Hiroki Sugiyama, Masafumi Arai, Hideo Ogawa   +3 more
doaj   +1 more source

Curcumin encapsulation using dendrimer PAMAM G4 conjugated with polyethylene glycol to improve the properties of gel dossage form [PDF]

Pharmaciana, 2018
Curcumin had a low bioavailability, to improve it than curcumin was encapsulated in the PAMAM dendrimer conjugated PEG. To facilitate topical use, curcumin dendrimer was combined with a carbomer 940 that can produce hydration conditions in the stratum ...
Rahmah Elfiyani , Yudi Srifiana, Faisal Dharojat Al Rasyied   +2 more
doaj   +1 more source

Amine functionalization of cholecyst-derived extracellular matrix with generation 1 PAMAM dendrimer [PDF]

, 2008
This document is the unedited author's version of a Submitted Work that was subsequently accepted for publication in Biomacromolecules, copyright © American Chemical Society after peer review.
Angele P., Babensee J. E., Badylak S., Badylak S. F., Badylak S. F., Badylak S. F., Billiar K., Brody S., Burugapalli K., Buttafoco L., Chandrasekar D., Charulatha V., Chen R. R., Coburn J. C., Curotto E., Domanski D. M., Duan X., Duan X., Duan X., DuBay D. A., Dumas P., Ferrando J. M., Garcia Y., Grinnell F., Henry J. A., Hodde J., Hodde J. P., Ko R., Kochupura P. V., Koizumi N. J., Lee J. M., Lee S. H., Liang H. C., Ma L., Ma Z., Malafaya P. B., McDevitt C. A., McKegney M., Meinert M., Najlah M., Nourse A., Olde Damink L. H., Olde Damink L. H., Osborne C. S., Papagiannaros A., Pek Y. S., Pieper J. S., Saito H., Sokolsky-Papkov M., Tabata Y., Tessmar J. K., Unsworth J. M., van Wachem P. B., van Wachem P. B., van Wachem P. B., Voytik-Harbin S. L., Wissink M. J., Wissink M. J., Wolkers W. F., Yee N., Zhong S., Zilla P.   +61 more
core   +1 more source