Results 11 to 20 of about 13,725 (223)
Concerted Action of Targeted Nucleic Acid Therapeutics as Flexible, Precision and Personalized Cancer Treatment. [PDF]
Adv Sci (Weinh)Combinations of small activating RNAs and small interfering RNAs were developed as personalized precision therapies that simultaneously activate tumor suppressors and silence oncogenes according to the molecular signatures of patient tumors. This combination strategy demonstrated superior anticancer efficacy, highlighting the promise of precision ...
Wu J +18 more
europepmc +2 more sources
Oxygels: Tunable Phosphorescent Hydrogels for Cherenkov-Excited Luminescence Imaging (CELI) of Oxygen. [PDF]
Adv Healthc MaterBiocompatible hydrogels with covalently embedded near‐infrared phosphorescent probes enable local tissue pO2 quantification by means of Cherenkov‐excited luminescence imaging (CELI), where optical excitation occurs within tissues upon irradiation with high‐energy electron beams.
Belali S +7 more
europepmc +2 more sources
Cytotoxicity of Dendrimers [PDF]
Biomolecules, 2019 Drug delivery systems are molecular platforms in which an active compound is packed into or loaded on a biocompatible nanoparticle. Such a solution improves the activity of the applied drug or decreases its side effects. Dendrimers are promising molecular platforms for drug delivery due to their unique properties.
Anna Janaszewska +4 more
openaire +3 more sources
Review Dendrimer : Definisi, Sintesis, Aplikasi Dan Prospektif
Jurnal Kimia dan Kemasan, 2013 Dendrimer merupakan makrostruktur monodisperse dengan banyak cabang yang homogen dan degree of branching (DB) 100%. Dua cara sintesis dendrimer yaitu convergent dan divergent dilakukan.
Dwinna Rahmi
doaj +1 more source
Curcumin encapsulation using dendrimer PAMAM G4 conjugated with polyethylene glycol to improve the properties of gel dossage form [PDF]
Pharmaciana, 2018 Curcumin had a low bioavailability, to improve it than curcumin was encapsulated in the PAMAM dendrimer conjugated PEG. To facilitate topical use, curcumin dendrimer was combined with a carbomer 940 that can produce hydration conditions in the stratum ...
Rahmah Elfiyani +2 more
doaj +1 more source
Turn-on Type Chemical Sensing of Vitamin K4 by Fluorene Dendrimers with Naphthalene Segments
Molecules, 2014 G1 and G2 fluorene dendrimers with naphthalene termini were synthesized as a fluorescence turn-on type chemical sensor for vitamin K4. The fluorene dendrimers were prepared by Williamson ether reaction between the fluorene core with dihydroxy groups and ...
Naoya Adachi +3 more
doaj +1 more source
Sensors, 2015 Recently, we developed novel chiral dendrimer-triamine-coordinated Gd-MRI contrast agents (Gd-MRI CAs), which showed longitudinal relaxivity (r1) values about four times higher than that of clinically used Gd-DTPA (Magnevist®, Bayer).
Yuka Miyake +8 more
doaj +1 more source
Scientific Reports, 2018 Dendrimers exhibit super atomistic features by virtue of their well-defined discrete quantized nanoscale structures. Here, we show that hyperbranched amine-terminated polyamidoamine (PAMAM) dendrimer G4.0 reacts with linear polyethylene glycol (PEG ...
Juan Wang, Hu Yang
doaj +1 more source
Erlotinib-Loaded Dendrimer Nanocomposites as a Targeted Lung Cancer Chemotherapy
Molecules, 2023 Lung cancer is the main cause of cancer-related mortality globally. Erlotinib is a tyrosine kinase inhibitor, affecting both cancerous cell proliferation and survival.
Wafa K. Fatani +9 more
doaj +1 more source