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Antioxidant Action by Gold−PAMAM Dendrimer Nanocomposites
Langmuir, 2004Gold-dendrimer nanocomposites were prepared in the presence of poly(amidoamine) (PAMAM) dendrimer (generation 3, 3.5, 5, and 5.5) via reduction of HAuCl4 with sodium borohydride. The average particle size of the gold nanoparticles was independent of the dendrimer concentration, ranging between 3.0 and 4.3 nm in diameter. The catalytic activities of the
Kunio, Esumi +2 more
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Convergent Synthesis of Internally Branched PAMAM Dendrimers
Organic Letters, 2005[reaction: see text] A series of aliphatic internally branched poly(amido amine) dendrons and dendrimers has been synthesized. The internal branching unit was 1,2-propanediamine and a series of PAMAM-type dendrons of the types AB2, AB4, and AB8 were built.
Pittelkow, Michael +1 more
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Mechanism of PAMAM Dendrimers Internalization in Hippocampal Neurons
Molecular Pharmaceutics, 2016Polyamidoamine (PAMAM) dendrimers are hyperbranched macromolecules which have been described as one of the most promising drug nanocarrier systems. A key process to understand is their cellular internalization mechanism because of its direct influence on their intracellular distribution, association with organelles, entry kinetics, and cargo release ...
Felipe, Vidal +5 more
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DNA Assisted Self-Assembly of PAMAM Dendrimers
The Journal of Physical Chemistry B, 2014We report DNA assisted self-assembly of polyamidoamine (PAMAM) dendrimers using all atom Molecular Dynamics (MD) simulations and present a molecular level picture of a DNA-linked PAMAM dendrimer nanocluster, which was first experimentally reported by Choi et al. (Nano Lett., 2004, 4, 391-397). We have used single stranded DNA (ssDNA) to direct the self-
Mandal, Taraknath +2 more
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The influence of surface modification on the cytotoxicity of PAMAM dendrimers
International Journal of Pharmaceutics, 2003The influence of surface modification on the cytotoxicity of PAMAM dendrimers was examined using Caco-2 cells. Dendrimers were modified by conjugating either lauroyl chains or polyethylene glycol (PEG) 2000 onto the surface of cationic PAMAM dendrimers (G2, G3, G4).
Jevprasesphant, R. +5 more
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Unraveling the Photoluminescence Puzzle of PAMAM Dendrimers
Chemistry – A European Journal, 2011Shu-Yi, Lin +6 more
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Transepithelial transport and toxicity of PAMAM dendrimers: Implications for oral drug delivery
Advanced Drug Delivery Reviews, 2012Hamidreza Ghandehari
exaly