Results 11 to 20 of about 19,804 (212)

Fluorescent nanosized PAMAM dendrimers: One-step formation of a bright blue fluorophore on terminal groups and its optical properties [PDF]

open access: yesИзвестия Саратовского университета. Новая серия: Физика, 2023
Background and Objectives: Polyamidoamine dendrimers (PAMAM) are nanoscale monodisperse compounds with a multifunctional terminal surface. Structural features of PAMAM, such as a nanosize of high homogeneity, highly developed terminal surface and ...
Mordovina, Ekaterina Alekseevna   +7 more
doaj   +1 more source

Second-Generation Polyamidoamine Dendrimer Conjugated with Oligopeptides Can Enhance Plasmid DNA Delivery In Vitro

open access: yesMolecules, 2023
Poly(amidoamine) (PAMAM) dendrimers have attracted considerable attention in the field of gene therapy due to their flexibility in introducing different functional moieties and reduced toxicity at low generations.
Seongyeon Kim   +3 more
doaj   +1 more source

Effects of the surface charge of polyamidoamine dendrimers on cellular exocytosis and the exocytosis mechanism in multidrug-resistant breast cancer cells

open access: yesJournal of Nanobiotechnology, 2021
Background Polyamidoamine (PAMAM) dendrimer applications have extended from tumor cells to multidrug-resistant tumor cells. However, their transportation in multidrug-resistant tumor cells remains unclear.
Jie Zhang   +7 more
doaj   +1 more source

High Fluorescent Porphyrin-PAMAM-Fluorene Dendrimers [PDF]

open access: yesMolecules, 2015
Two new classes of dendrimers bearing 8 and 32 fluorene donor groups have been synthesized. The first and second generations of these porphyrin-PAMAM-fluorene dendrimers were characterized by 1H-NMR, 13C-NMR, FTIR, UV-vis spectroscopy, elemental analyses and MALDI-TOF mass spectrometry.
Garfias-Gonzalez, Karla   +6 more
openaire   +3 more sources

Multivalent Lactose–Ferrocene Conjugates Based on Poly (Amido Amine) Dendrimers and Gold Nanoparticles as Electrochemical Probes for Sensing Galectin-3

open access: yesNanomaterials, 2020
Galectin-3 is considered a cancer biomarker and bioindicator of fibrosis and cardiac remodeling and, therefore, it is desirable to develop convenient methods for its detection.
Manuel C. Martos-Maldonado   +3 more
doaj   +1 more source

Diagnostic and therapeutic applications of smart nanocomposite dendrimers

open access: yesFrontiers in Bioscience-Landmark, 2020
Dendrimers are three dimensional, multifunctional polymeric structures which are composed of a core and branches emanating from these structures, resembling a tree.
Vinay Kumar   +5 more
doaj   +1 more source

β-Cyclodextrin and Oligoarginine Peptide-Based Dendrimer-Entrapped Gold Nanoparticles for Improving Drug Delivery to the Inner Ear

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Here, we developed a safe and highly effective nanocarrier using β-cyclodextrin (β-CD) and oligoarginine peptide (Arg8)-modified dendrimer-entrapped gold nanoparticles (Au@CD-PAMAM-Arg8), with a diameter of 5 nm, for improved delivery of dexamethasone ...
Jia Luo   +4 more
doaj   +1 more source

A Review on Increasing the Targeting of PAMAM as Carriers in Glioma Therapy

open access: yesBiomedicines, 2022
Glioma is an invasive brain cancer, and it is difficult to achieve desired therapeutic effects due to the high postoperative recurrence rate and limited efficacy of drug therapy hindered by the biological barrier of brain tissue.
Xingyue Li   +4 more
doaj   +1 more source

Inverse Polyamidoamine (i‐PAMAM) Dendrimer Antimicrobials

open access: yesHelvetica Chimica Acta, 2023
AbstractHere we redesigned the branches of polyamidoamine (PAMAM) dendrimers by moving the amide carbonyl group on the other side of the amide nitrogen atom, transforming the β‐alaninyl‐amidoethylamine branch, which easily undergoes retro‐Michael reactions and renders PAMAMs intrinsically unstable, into a more stable glycyl‐amidopropylamine branch. The
Bonvin, Etienne, Reymond, Jean-Louis
openaire   +2 more sources

The inhibitory effect of carboxyl-terminated polyamidoamine dendrimers on dentine host-derived matrix metalloproteinases in vitro in an etch-and-rinse adhesive system [PDF]

open access: yesRoyal Society Open Science, 2019
The biomimetic remineralization of collagen fibrils has increased interest in restoring the demineralized dentine generated by dental caries. Carboxyl-terminated polyamidoamine dendrimers (PAMAM-COOH), hyperbranched polymeric macromolecules, can act as ...
Qian Wu   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy