Self‐Amplified Activatable Fluorescent Probe for Early Diagnosis of Acute Kidney Injury and High‐Throughput Screening of Natural Protectants [PDF]
The PS‐QRC nanoprobe employs L‐serine as a targeting ligand for kidney injury molecule‐1 (KIM‐1) to achieve accumulation in injured renal tissues. Upon activation by reactive oxygen species (ROS), it undergoes a self‐amplifying cascade to release fluorophores for near‐infrared fluorescence (NIRF) imaging, enabling ultra‐early diagnosis of acute kidney ...
Yahui Chen +10 more
wiley +2 more sources
It is crucial to emphasize the biomineralization therapeutic method to repair etched dentin in clinic. Non-collagenous proteins (NCPs) play critical role in the biomineralization of dentine. In this paper, we synthesized the phosphate-terminated polyamidoamine dendrimer (PAMAM-PO3H2) by one-step modification successfully and examined by Fourier ...
QIN, Hejia +4 more
openaire +3 more sources
Temperature-responsive nanocarrier systems using external stimuli are one of the most widely investigated stimuli-responsive strategies because heat is easy and safe to use for hyperthermia and controlled drug delivery.
Takuya Hashimoto +4 more
doaj +1 more source
PAMAM-Lys, a novel vaccine delivery vector, enhances the protective effects of the SjC23 DNA vaccine against Schistosoma japonicum infection. [PDF]
BACKGROUND: Schistosomiasis japonica remains a major public-health concern in China. Praziquantel-based chemotherapy effectively reduces both infections and intensity; however, it can not prevent re-infection.
Xiaoting Wang +10 more
doaj +1 more source
Intrinsic Blue Fluorescence of 2.0G PAMAM-DCM Polymer Dots and Its Applications for Fe3+ Sensing
A typical and environment-friendly fluorescent polyamine-amine (PAMAM) features good compatibility and unique surface modification, while it is restricted by a low fluorescence property performance and an unclear fluorescence mechanism.
Xin Wang +8 more
doaj +1 more source
Biogenic and synthetic polyamines bind cationic dendrimers.
Biogenic polyamines are essential for cell growth and differentiation, while polyamine analogues exert antitumor activity in multiple experimental model systems, including breast and lung cancer.
Jean-Sebastian Mandeville +3 more
doaj +1 more source
Herein, we report a feasible approach for preparation of crosslinked alginate (Alg) and poly(amido amine) (PAMAM) nanogels (Alg-PAMAM NGs), using a water-in-oil-in-water (w/o/w) double emulsion route, via strong electrostatic interactions between anionic
A. Córdoba +5 more
doaj +1 more source
Dendritic Poly (amidoamine) Functionalized with Magnetic Nanoparticles as Sorbent for Simultaneous Magnetic Solid-Phase Extraction of Miconazole, Clotrimazole and Tioconazole Followed by Determination via HPLC-UV [PDF]
In this study, an attempt was made to synthesize a new sorbent based on the second generation of silica coated magnetic poly(amidoamine) (Fe3O4@SiO2@PAMAM) to improve the performance of magnetic solid phase extraction (MSPE) of some antifungal drugs ...
Mohsen Shirkhodayekashani +3 more
doaj +1 more source
Convergent Synthesis of PAMAM-like Dendrimers from Azide-functionalized PAMAM Dendrons [PDF]
The convergent synthesis of symmetric PAMAM-like dendrimers from azide-functionalized poly(amido- amine) (PAMAM) dendrons and two different multi-alkynes was investigated. The stitching method was based on the click chemistry protocol, i.e., the copper-catalyzed cycloaddition reaction between an alkyne and an azide.
openaire +1 more source
The Structure of PAMAM DAB-dendr(NH2)4 – the First Crystal Structure of a PAMAM-Dendrimer [PDF]
The first crystal structure of an amino terminated PAMAM-dendrimer (DABdendr(NH2)4) is reported. The structure features a compact dendrimer conformation without voids, held together by intermolecular hydrogen bonds between ...
Jesper Bendix, Joern Christensen
openaire +1 more source

