DNA microarrays with PAMAM dendritic linker systems [PDF]
The DNA microarray-based analysis of single nucleotide polymorphisms (SNPs) is important for the correlation of genetic variations and individual phenotypes, and for locating disease-causing genes. To facilitate the development of surfaces suitable for immobilization of oligonucleotides, we report here a novel method for the surface immobilization of ...
Rüdiger, Benters +4 more
openaire +2 more sources
Herein, we report a feasible approach for preparation of crosslinked alginate (Alg) and poly(amido amine) (PAMAM) nanogels (Alg-PAMAM NGs), using a water-in-oil-in-water (w/o/w) double emulsion route, via strong electrostatic interactions between anionic
A. Córdoba +5 more
doaj +1 more source
Structure of polyamidoamide dendrimers up to limiting generations : a mesoscale description [PDF]
The polyamidoamide (PAMAM) class of dendrimers was one of the first dendrimers synthesized by Tomalia and co-workers at Dow. Since its discovery the PAMAMs have stimulated many discussions on the structure and dynamics of such hyperbranched polymers ...
Goddard, William A., III +3 more
core +1 more source
Biogenic and synthetic polyamines bind cationic dendrimers.
Biogenic polyamines are essential for cell growth and differentiation, while polyamine analogues exert antitumor activity in multiple experimental model systems, including breast and lung cancer.
Jean-Sebastian Mandeville +3 more
doaj +1 more source
Intrinsic Blue Fluorescence of 2.0G PAMAM-DCM Polymer Dots and Its Applications for Fe3+ Sensing
A typical and environment-friendly fluorescent polyamine-amine (PAMAM) features good compatibility and unique surface modification, while it is restricted by a low fluorescence property performance and an unclear fluorescence mechanism.
Xin Wang +8 more
doaj +1 more source
G4.5 Pamam Dendrimer-Risperidone: Biodistribution and Behavioral Changes in In Vivo Model [PDF]
Dendritic polymers are considered as emerging and outstanding carriers as modern medicinal systems due to their derivatisable branched architecture and possibility to modify them in numerous ways.
Alonso, Silvia del Valle +6 more
core +2 more sources
Slow-Release Formulation of Cowpea Mosaic Virus for In Situ Vaccine Delivery to Treat Ovarian Cancer. [PDF]
The plant viral nanoparticle cowpea mosaic virus (CPMV) is shown to be an effective immunotherapy for ovarian cancer when administered as in situ vaccine weekly, directly into the intraperitoneal (IP) space in mice with disseminated tumors.
Aguirre +41 more
core +2 more sources
Dendritic Poly (amidoamine) Functionalized with Magnetic Nanoparticles as Sorbent for Simultaneous Magnetic Solid-Phase Extraction of Miconazole, Clotrimazole and Tioconazole Followed by Determination via HPLC-UV [PDF]
In this study, an attempt was made to synthesize a new sorbent based on the second generation of silica coated magnetic poly(amidoamine) (Fe3O4@SiO2@PAMAM) to improve the performance of magnetic solid phase extraction (MSPE) of some antifungal drugs ...
Mohsen Shirkhodayekashani +3 more
doaj +1 more source
Dendritic glycopolymers based on dendritic polyamine scaffolds: view on their synthetic approaches, characteristics and potential for biomedical applications [PDF]
In this review we highlight the potential for biomedical applications of dendritic glycopolymers based on polyamine scaffolds. The complex interplay of the molecular characteristics of the dendritic architectures and their specific interactions with ...
Abbott +278 more
core +2 more sources
Polyethylene glycolated PAMAM dendrimers-Efavirenz conjugates
The preparation of novel PEGylated PAMAM (poly-amidoamine) dendrimers for delivery of anti-HIV drug Efavirenz is reported.About 5.0 G PAMAM dendrimers are prepared by ethylene diamine core via Michael addition by divergent method. PEGylation is done by polyethylene glycol 600 using epichlorhydrin as linker.
Pyreddy, Suneela +2 more
openaire +3 more sources

