Results 1 to 10 of about 5,578 (166)
A UiO-66-NH2 MOF/PAMAM Dendrimer Nanocomposite for Electrochemical Detection of Tramadol in the Presence of Acetaminophen in Pharmaceutical Formulations [PDF]
Biosensors, 2023 In this work, we prepared a novel electrochemical sensor for the detection of tramadol based on a UiO-66-NH2 metal–organic framework (UiO-66-NH2 MOF)/third-generation poly(amidoamine) dendrimer (G3-PAMAM dendrimer) nanocomposite drop-cast onto a glassy ...
Fariba Garkani Nejad +2 more
doaj +2 more sources
The Effect of Absorption-Enhancement and the Mechanism of the PAMAM Dendrimer on Poorly Absorbable Drugs [PDF]
Molecules, 2018 The polyamidoamine (PAMAM) dendrimer is a highly efficient absorption promoter. In the present study, we studied the absorption-enhancing effects and the mechanism of PAMAM dendrimers with generation 0 to generation 3 (G0–G3) and concentrations (0 ...
Juan Lu +9 more
doaj +2 more sources
Molecules, 2021 We have developed a convenient and selective method for the detection of Gram-positive bacteria using a ditopic poly(amidoamine) (PAMAM) dendrimer probe.
Ayame Mikagi +6 more
doaj +1 more source
PAMAM dendrimers for the delivery of the antibacterial Triclosan [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2008 Many oral care products incorporate an antibacterial compound to prevent the formation of dental plaque which predisposes teeth to dental caries or periodontal disease. Triclosan (TCN) is a commonly used antiplaque agent in toothpastes. Strategies to increase the delivery efficiency of antibacterials using formulation aids such as polyamidoamine (PAMAM)
Gardiner, Jonathan; id_orcid 0000-0003-1827-6817 +5 more
openaire +3 more sources
Erlotinib-Loaded Dendrimer Nanocomposites as a Targeted Lung Cancer Chemotherapy
Molecules, 2023 Lung cancer is the main cause of cancer-related mortality globally. Erlotinib is a tyrosine kinase inhibitor, affecting both cancerous cell proliferation and survival.
Wafa K. Fatani +9 more
doaj +1 more source
Paramagnetic NMR investigation of dendrimer-based host-guest interactions. [PDF]
PLoS ONE, 2013 In this study, the host-guest behavior of poly(amidoamine) (PAMAM) dendrimers bearing amine, hydroxyl, or carboxylate surface functionalities were investigated by paramagnetic NMR studies.
Fei Wang, Naimin Shao, Yiyun Cheng
doaj +1 more source
Pharmaceutics, 2022 Aim: The influence of the physiochemical properties of dendrimer nanoparticles on cardiac contractility and hemodynamics are not known. Herein, we investigated (a) the effect of polyamidoamine (PAMAM) dendrimer generation (G7, G6, G5, G4 and G3) and ...
Saghir Akhtar +3 more
doaj +1 more source
New Dendrimers: Synthesis and Characterization of POPAM−PAMAM Hybrid Dendrimers [PDF]
Macromolecules, 2008 Recently developed multifunctional cancer therapeutic nano-device production is based on poly(amidoamine) PAMAM generation 5 (G5) dendrimer as a carrier 1-5. Scale up synthesis of this nano-device is limited because of long reaction sequence (12 reaction steps) and long and not easy work up of the products after each reaction step.
István J, Majoros +3 more
openaire +2 more sources
Targeted drug delivery of capecitabine to mice xenograft gastric cancer by PAMAM dendrimer nanocarrier [PDF]
African Journal of Gastroenterology and Hepatology, 2019 Aims: This study used an animal xenograft model of gastric cancer induction to investigate the therapeutic effects of capecitabine polyamidoamine (PAMAM) dendrimer complex against cancer and its potential side effects.
Sharareh Jafari +5 more
doaj +1 more source
Molecules, 2018 Clinical applications of many small molecules are limited due to poor solubility and lack of controlled release besides lack of other desirable properties.
Daniel M. Shadrack +4 more
doaj +1 more source