Comparative Evaluation of Lipofectamine and Dendrimer for Transfection of Short RNA Into Human T47D and MCF-10A Cell Lines [PDF]
Advanced Pharmaceutical Bulletin, 2023 Purpose: Non-viral transfection approaches are extensively used in cancer therapy. The future of cancer therapy lies on targeted and efficient drug/gene delivery.
Zohreh Jahanafrooz +2 more
doaj +1 more source
Effect of Terminal Groups of Dendrimers in the Complexation with Antisense Oligonucleotides and Cell Uptake [PDF]
, 2016 Indexación: Web of Science.Poly(amidoamine) dendrimers are the most recognized class of dendrimer. Amino-terminated (PAMAM-NH2) and hydroxyl-terminated (PAMAM-OH) dendrimers of generation 4 are widely used, since they are commercially available.
Araya-Durán, Ingrid +10 more
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Structure of polyamidoamide dendrimers up to limiting generations : a mesoscale description [PDF]
, 2009 The polyamidoamide (PAMAM) class of dendrimers was one of the first dendrimers synthesized by Tomalia and co-workers at Dow. Since its discovery the PAMAMs have stimulated many discussions on the structure and dynamics of such hyperbranched polymers ...
Goddard, William A., III +3 more
core +1 more source
Label-Free Detection of Saxitoxin with Field-Effect Device-Based Biosensor
Nanomaterials, 2022 Saxitoxin (STX) is a highly toxic and widely distributed paralytic shellfish toxin (PSP), posing a serious hazard to the environment and human health. Thus, it is highly required to develop new STX detection approaches that are convenient, desirable, and
Najeeb Ullah +5 more
doaj +1 more source
Polyethylene glycolated PAMAM dendrimers-Efavirenz conjugates
International Journal of Pharmaceutical Investigation, 2014 The preparation of novel PEGylated PAMAM (poly-amidoamine) dendrimers for delivery of anti-HIV drug Efavirenz is reported.About 5.0 G PAMAM dendrimers are prepared by ethylene diamine core via Michael addition by divergent method. PEGylation is done by polyethylene glycol 600 using epichlorhydrin as linker.
Pyreddy, Suneela +2 more
openaire +3 more sources
MicroRNAs delivery into human cells grown on 3D-printed PLA scaffolds coated with a novel fluorescent PAMAM dendrimer for biomedical applications [PDF]
, 2018 Many advanced synthetic, natural, degradable or non-degradable materials have been employed to create scaffolds for cell culture for biomedical or tissue engineering applications. One of the most versatile material is poly-lactide (PLA), commonly used as
Abbaszadeh, Zeinab +7 more
core +2 more sources
Curcumin encapsulation using dendrimer PAMAM G4 conjugated with polyethylene glycol to improve the properties of gel dossage form [PDF]
Pharmaciana, 2018 Curcumin had a low bioavailability, to improve it than curcumin was encapsulated in the PAMAM dendrimer conjugated PEG. To facilitate topical use, curcumin dendrimer was combined with a carbomer 940 that can produce hydration conditions in the stratum ...
Rahmah Elfiyani +2 more
doaj +1 more source
Structure of poly(propyl ether imine) (PETIM) dendrimer from fully atomistic molecular Dynamics Simulation and by Small Angle X-ray scattering [PDF]
, 2006 We study the structure of carboxylic acid terminated neutral poly (propyl ether imine) (PETIM) dendrimer from generation 1 through 6 (G1-G6) in a good solvent (water) by fully atomistic molecular dynamics (MD) simulations.
A. K. Sood +8 more
core +2 more sources
Intrinsic Fluorescence of PAMAM Dendrimers—Quenching Studies [PDF]
Polymers, 2018 Intrinsic, non-traditional fluorescence of polyamidoamine (PAMAM) dendrimers that do not possess classical fluorophores has been attracting considerable interest for the last decade. Many hypotheses regarding the source of the fluorescence have appeared, but some of them are still disputable.
Malgorzata Konopka +2 more
openaire +2 more sources
Biophysical and biological contributions of polyamine-coated carbon nanotubes and bidimensional buckypapers in the delivery of miRNAs to human cells [PDF]
, 2017 Recent findings in nanomedicine have revealed that carbon nanotubes (CNTs) can be used as potential drug carriers, therapeutic agents and diagnostics tools.
Bordi, Federico +9 more
core +2 more sources