Results 21 to 30 of about 5,727 (183)

Inverse Polyamidoamine (i‐PAMAM) Dendrimer Antimicrobials

Helvetica Chimica Acta, 2023
AbstractHere we redesigned the branches of polyamidoamine (PAMAM) dendrimers by moving the amide carbonyl group on the other side of the amide nitrogen atom, transforming the β‐alaninyl‐amidoethylamine branch, which easily undergoes retro‐Michael reactions and renders PAMAMs intrinsically unstable, into a more stable glycyl‐amidopropylamine branch. The
Bonvin, Etienne, Reymond, Jean-Louis
openaire   +2 more sources

Effects of the surface charge of polyamidoamine dendrimers on cellular exocytosis and the exocytosis mechanism in multidrug-resistant breast cancer cells

Journal of Nanobiotechnology, 2021
Background Polyamidoamine (PAMAM) dendrimer applications have extended from tumor cells to multidrug-resistant tumor cells. However, their transportation in multidrug-resistant tumor cells remains unclear.
Jie Zhang, Mingjuan Li, Mingyue Wang, Hang Xu, Zhuoxiang Wang, Yue Li, Baoyue Ding, Jianqing Gao   +7 more
doaj   +1 more source

Toxicity of Hexyl Acrylate Modified PAMAM Dendrimer [PDF]

Trends in Pharmaceutical Sciences, 2018
The aim of this study was to evaluate the effect of the hexyl acrylate conjugated polyamidoamine (PAMSM) dendrimer on different cell lines in the presence and absence of serum.
Mohammad Ashkan Naderian, Amin Reza Akbarizadeh, Akram Jamshidzadeh, Ali Dehshahri   +3 more
doaj  

The application of poly(amidoamine) dendrimers for modification of jute yarns: Preparation and dyeing properties

Journal of Saudi Chemical Society, 2015
In this study, poly(amidoamine) (PAMAM) G-2 dendrimer was used for jute yarn. Fourier transform infrared spectroscopy (FT-IR) revealed that all carbonyl groups of jute fibers reacted with amino groups of polyamidoamine dendrimers.
Ali Akbar Zolriasatein, Mohammad Esmail Yazdanshenas, Ramin Khajavi, Abosaeed Rashidi   +3 more
doaj   +1 more source

Kajian Dendrimer (Poly)Amidoamine (Pamam) Generasi 4 Sebagai Template Dalam Pembentukan Nanopartikel Secara In Silico

Journal of Tropical Pharmacy and Chemistry, 2017
Dendrimers are a class of highly branched synthetic polymers that has spherical form consist of three components: core, branch and terminal functional groups. One of dendrimer that has been commercialized is (Poly)amidoamine (PAMAM).
Yurika Sastyarina, Zuhrotun Nafisah, Muhammad Yusuf, Martalena Ramli, Abdul Mutalib, Ukun Soedjanaatmadja   +5 more
doaj   +1 more source

Best Practices for Purification and Characterization of PAMAM Dendrimer [PDF]

Macromolecules, 2012
Poly(amidoamine) (PAMAM) dendrimer are branched polymers with low degrees of heterogeneity. Current synthesis methods, however, result in substantial batch variability. We present our optimized procedure for post-synthesis (and post-market) purification of a generation 5 PAMAM dendrimer by membrane dialysis and demonstrate its effectiveness and ...
Douglas G, Mullen, Ankur, Desai, Mallory A, van Dongen, Mark, Barash, James R, Baker, Mark M, Banaszak Holl   +5 more
openaire   +2 more sources

An Available Strategy for Nasal Brain Transport of Nanocomposite Based on PAMAM Dendrimers via In Situ Gel

Nanomaterials, 2019
Polyamidoamine (PAMAM) dendrimers are efficient drug carriers. The presence of a physiological pathway for nasal brain transport provides a potential path for direct brain-targeted delivery of dendrimer nanocomposites. In this study, we synthesized PAMAM
Huichao Xie, Lingjun Li, Yue Sun, Yuzhen Wang, Shuang Gao, Yuan Tian, Xuemei Ma, Chengcheng Guo, Fumin Bo, Li Zhang   +9 more
doaj   +1 more source

On-Demand Bioadhesive Dendrimers with Reduced Cytotoxicity

Molecules, 2018
Tissue adhesives based on polyamidoamine (PAMAM) dendrimer, grafted with UV-sensitive aryldiazirine (PAMAM-g-diazirine) are promising new candidates for light active adhesion on soft tissues.
Feng Gao, Ivan Djordjevic, Oleksandr Pokholenko, Haobo Zhang, Junying Zhang, Terry W. J. Steele   +5 more
doaj   +1 more source

Thermodynamic Interaction between PAMAM G4-NH2, G4-OH, G3.5-COONa Dendrimers and Gemcitabine in Water Sotutions

International Journal of Secondary Metabolite, 2016
The thermodynamics of complex formation of polyamideamine dendrimers: cationic PAMAM G4-NH2, neutral PAMAM G4-OH and anionic PAMAM G3.5-COONa with gemcitabine hydrochloride, an antitumor drug, in water at a temperature of 250C was studied.
Bartlomiej Palecz, Adam Buczkowski, Henryk Piekarski, Özge Kılınçarslan   +3 more
doaj   +3 more sources

Dendrimer-based selective autophagy-induction rescues ΔF508-CFTR and inhibits Pseudomonas aeruginosa infection in cystic fibrosis.

PLoS ONE, 2017
BackgroundCystic Fibrosis (CF) is a genetic disorder caused by mutation(s) in the CF-transmembrane conductance regulator (Cftr) gene. The most common mutation, ΔF508, leads to accumulation of defective-CFTR protein in aggresome-bodies.
Scott Mackenzie Brockman, Manish Bodas, David Silverberg, Ajit Sharma, Neeraj Vij   +4 more
doaj   +1 more source