Journal of Nanobiotechnology, 2021 Background Polyamidoamine (PAMAM) dendrimer applications have extended from tumor cells to multidrug-resistant tumor cells. However, their transportation in multidrug-resistant tumor cells remains unclear.
Jie Zhang +7 more
doaj +1 more source
Molecular Dynamics Study of Charged Dendrimers in Salt-Free Solution: Effect of Counterions [PDF]
, 2005 Polyamidoamine (PAMAM) dendrimers, being protonated under physiological conditions, represent a promising class of nonviral, nano-sized vectors for drug and gene delivery. We performed extensive molecular dynamics simulations of a generic model dendrimer
Andrey A. Gurtovenko +4 more
core +3 more sources
Toxicity of Hexyl Acrylate Modified PAMAM Dendrimer [PDF]
Trends in Pharmaceutical Sciences, 2018 The aim of this study was to evaluate the effect of the hexyl acrylate conjugated polyamidoamine (PAMSM) dendrimer on different cell lines in the presence and absence of serum.
Mohammad Ashkan Naderian +3 more
doaj
Journal of Saudi Chemical Society, 2015 In this study, poly(amidoamine) (PAMAM) G-2 dendrimer was used for jute yarn. Fourier transform infrared spectroscopy (FT-IR) revealed that all carbonyl groups of jute fibers reacted with amino groups of polyamidoamine dendrimers.
Ali Akbar Zolriasatein +3 more
doaj +1 more source
Dendritic glycopolymers based on dendritic polyamine scaffolds: view on their synthetic approaches, characteristics and potential for biomedical applications [PDF]
, 2014 In this review we highlight the potential for biomedical applications of dendritic glycopolymers based on polyamine scaffolds. The complex interplay of the molecular characteristics of the dendritic architectures and their specific interactions with ...
Abbott +278 more
core +2 more sources
Cationic PAMAM Dendrimers Disrupt Key Platelet Functions [PDF]
Molecular Pharmaceutics, 2012 Poly(amidoamine) (PAMAM) dendrimers have been proposed for a variety of biomedical applications and are increasingly studied as model nanomaterials for such use. The dendritic structure features both modular synthetic control of molecular size and shape and presentation of multiple equivalent terminal groups.
Clinton F, Jones +12 more
openaire +2 more sources
G4.5 Pamam Dendrimer-Risperidone: Biodistribution and Behavioral Changes in In Vivo Model [PDF]
, 2013 Dendritic polymers are considered as emerging and outstanding carriers as modern medicinal systems due to their derivatisable branched architecture and possibility to modify them in numerous ways.
Alonso, Silvia del Valle +6 more
core +2 more sources
Slow-Release Formulation of Cowpea Mosaic Virus for In Situ Vaccine Delivery to Treat Ovarian Cancer. [PDF]
, 2018 The plant viral nanoparticle cowpea mosaic virus (CPMV) is shown to be an effective immunotherapy for ovarian cancer when administered as in situ vaccine weekly, directly into the intraperitoneal (IP) space in mice with disseminated tumors.
Aguirre +41 more
core +2 more sources
Generation 3 PAMAM dendrimer TAMRA conjugates containing precise dye/dendrimer ratios [PDF]
Materials Today Communications, 2015 The synthesis, isolation, and characterization of generation 3 poly(amidoamine) (G3 PAMAM) dendrimer containing precise ratios of 5-carboxytetramethylrhodamine succinimidyl ester (TAMRA) dye (n = 1-3) per polymer particle are reported. Stochastic conjugation of TAMRA dye to the dendrimer was followed by separation into precise dye-polymer ratios using ...
Janet, Manono +5 more
openaire +2 more sources
Understanding Effects of PAMAM Dendrimer Size and Surface Chemistry on Serum Protein Binding with Discrete Molecular Dynamics Simulations. [PDF]
ACS Sustain Chem Eng, 2018 Polyamidoamine (PAMAM) dendrimers, a class of polymeric nanoparticles (NPs) with highly-controllable sizes and surface chemistry, are promising candidates for many biomedical applications, including drug and gene delivery, imaging, and inhibition of ...
Wang B +5 more
europepmc +2 more sources