Results 51 to 60 of about 5,727 (183)

Comparison of generation 3 polyamidoamine dendrimer and generation 4 polypropylenimine dendrimer on drug loading, complex structure, release behavior, and cytotoxicity

International Journal of Nanomedicine, 2011
Naimin Shao1, Yunzhang Su1, Jingjing Hu2, Jiahai Zhang3, Hongfeng Zhang1, Yiyun Cheng1,41School of Life Sciences, East China Normal University, Shanghai, 2CAS Key Laboratory of Soft Matter Chemistry, Department of Chemistry, University of Science and ...
Shao N, Su Y, Hu J, Zhang J, Zhang H, Cheng Y   +5 more
doaj  

Tailored for Binding: Alanine‐Modified Poly(1‐Naphthylamine) Targets Serum Albumins

Polymer Engineering &Science, EarlyView.
Alanine modified poly(1‐naphthylamine). ABSTRACT This study presents a new approach for modifying the structural and functional properties of poly(1‐naphthylamine) (PNA) by incorporating the amino acid alanine (Ala) in different molar proportions (80/20, 50/50, and 20/80 for PNA/Ala) through an ultrasound‐assisted polymerization process.
Nuzhat Nabi, Ufana Riaz
wiley   +1 more source

Chemistry of Secondary Metabolites (Production, Properties, Biological Activity, etc.): Solubility Study of the Interaction between Pamam G-3 Dendrimer and 5 Fluorouracil in Aqueous Solution

International Journal of Secondary Metabolite, 2016
Poly(amidoamine) dendrimers (PAMAM) are polymeric macromolecules that can find their use as carriers of small ligand molecules such as cosmetics and drugs.
B. PALECZ, A. BUCZKOWSKI, L. B. ZAVODNIK   +2 more
doaj  

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

Responsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan, Chenlong Zhou, Shuaikang Yang, Zhenduo Chen, Guanghui Zhao, Qi Tang, Haoyu Yan, Feng Li, Xi Ma   +8 more
wiley   +1 more source

Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein

Results in Physics, 2018
In this work, cadmium sulfide quantum dots composited with polyamidoamine dendrimer (CdSQDs-PAMAM) thin film had been successfully developed for use in the detection of dengue virus (DENV) E-proteins.
Nur Alia Sheh Omar, Yap Wing Fen, Jaafar Abdullah, Nur Ain Asyiqin Anas, Nur Syahira Md Ramdzan, Mohd Adzir Mahdi   +5 more
doaj   +1 more source

Active pH Modulation by Proton Channel‐Peptide Nucleic Acid Complex for Effective siRNA Endosomal Escape

Small, EarlyView.
A bioinspired siRNA nanocarrier is engineered by integrating an influenza A M2 proton channel with siRNA through a peptide nucleic acid linker on liposome surfaces. Active proton transport amplifies osmotic stress within endosomes, triggering membrane rupture and cytosolic release.
Seongmin Ga, Nam Hyeong Kim, Si Yeon Ryu, Kyeonghyun Kim, Eun Sung Kang, Hayeon Bae, Seungmin Ryu, Suhyeon Kim, Yeontae Jang, Bok‐Soo Lee, Jiyoung Nam, Minah Suh, Jaecheol Lee, Seung‐gu Kang, Jaekyung Hyun, Huong T. Kratochvil, Yong Ho Kim   +16 more
wiley   +1 more source

Preferential and Increased Uptake of Hydroxyl-Terminated PAMAM Dendrimers by Activated Microglia in Rabbit Brain Mixed Glial Culture

Molecules, 2018
Polyamidoamine (PAMAM) dendrimers are multifunctional nanoparticles with tunable physicochemical features, making them promising candidates for targeted drug delivery in the central nervous system (CNS).
Yossef Alnasser, Siva P. Kambhampati, Elizabeth Nance, Labchan Rajbhandari, Shiva Shrestha, Arun Venkatesan, Rangaramanujam M. Kannan, Sujatha Kannan   +7 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, Volume 38, Issue 51, 11 September 2026.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Dendrimer-coated carbon nanotubes deliver dsRNA and increase the efficacy of gene knockdown in the red flour beetle Tribolium castaneum

Scientific Reports, 2020
In this study, the use of dendrimer-coated carbon nanotubes (CNTs) as a delivery vehicle for dsRNA was assessed in Tribolium castaneum. Exposure to low dosages of polyamidoamine dendrimer carbon nanotubes (PAMAM-CNTs) did not affect T.
Catriona H. Edwards, Craig R. Christie, Andrea Masotti, Antonella Celluzzi, Andrea Caporali, Ewan M. Campbell   +5 more
doaj   +1 more source

Bioapplications of poly(amidoamine) (PAMAM) dendrimers in nanomedicine

Journal of Nanoparticle Research, 2014
Poly(amidoamine) (PAMAM) dendrimers are a novel class of spherical, well-designed branching polymers with interior cavities and abundant terminal groups on the surface which can form stable complexes with drugs, plasmid DNA, oligonucleotides, and antibodies.
Pourianazar, Negar Taghavi, Mutlu, Pelin, Gunduz, Ufuk   +2 more
openaire   +2 more sources