Results 51 to 60 of about 41,761 (267)

Folate-conjugated nanoparticles as a potent therapeutic approach in targeted cancer therapy [PDF]

, 2015
The selective and efficient drug delivery to tumor cells can remarkably improve different cancer therapeutic approaches. There are several nanoparticles (NPs) which can act as a potent drug carrier for cancer therapy.
Bahrami, B., Bakhshaei, P., Ghalamfarsa, G., Hojjat-Farsangi, M., Jadidi-Niaragh, F., Mohammadnia-Afrouzi, M., Sadreddini, S., Yazdani, Y., Yousefi, M.   +8 more
core   +1 more source

A novel RGDyC/PEG co-modified PAMAM dendrimer-loaded arsenic trioxide of glioma targeting delivery system

International Journal of Nanomedicine, 2018
Background The Traditional Chinese Medicine, arsenic trioxide (ATO, As2O3) could inhibit growth and induce apoptosis in a variety of solid tumor cells, but it is severely limited in the treatment of glioma due to its poor BBB penetration and ...
Yanping Lu, Shun-ping Han, Hongyue Zheng, Rui Ma, Y. Ping, Jiafeng Zou, Hongxia Tang, Yongping Zhang, Xiu-iing Xu, Fanzhu Li   +9 more
semanticscholar   +1 more source

Dendrimer and dendrimer gel‐derived drug delivery systems: Breaking bottlenecks of topical administration of glaucoma medications

MedComm – Biomaterials and Applications, 2023
Due to high structural flexibility, multidrug carrying capability, and tunable size, dendrimers have been used as suitable carriers for ophthalmic drug delivery. Drug molecules can be either encapsulated or chemically coupled to dendrimers.
Juan Wang, Boxuan Li, Uday B. Kompella, Hu Yang   +3 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Structure of DNA-Functionalized Dendrimer Nanoparticles

, 2012
Atomistic molecular dynamics simulations have been carried out to reveal the characteristic features of ethylenediamine (EDA) cored protonated poly amido amine (PAMAM) dendrimers of generation 3 (G3) and 4 (G4) that are functionalized with single ...
Aldaye, Alivisatos, Bao, Berendsen, Blab, Bliznyuk, Carbone, Choi, Choi, Condon, Dai, Dai, Duan, Esfand, Feldkamp, Gurtovenko, Hainfeld, Hill, Hsu, Huang, Hurst, Jain, Jain, Jorgensen, Kalogianni, Karatasos, Ke, Klos, Lara, Largo, Lee, Lee, Lee, Lee, Li, Liu, Lu, Lyulin, Macfarlane, Maiti, Maiti, Maiti, Maiti, Maiti, Mattaparthi Venkata Satish Kumar, Mayo, Mijovic, Mirkin, Mizutani, Nandy, Niemeyer, Niemeyer, Nykypanchuk, Paciotti, Padovan-Merhar, Park, Park, Pearlman, Prabal K Maiti, Rosi, Rosi, Ryckaert, Seeman, Sosinsky, Starr, Stechemesser, Storhoff, Suek, Sun, Thankappan, Tomalia, Tomalia, Tomalia, Tomalia, Tomalia, Uppuluri, Vasumathi, Xiong, Zhao   +78 more
core   +1 more source

Practical computational toolkits for dendrimers and dendrons structure design [PDF]

, 2017
Dendrimers and dendrons offer an excellent platform for developing novel drug delivery systems and medicines. The rational design and further development of these repetitively branched systems are restricted by difficulties in scalable synthesis and ...
A Kwok, A Quintana, AM Naylor, BP Roberts, C Yu, CD Schwieters, CW Brown, D Astruc, D Jishkariani, D Luong, DA Case, E Vacas-Córdoba, F Razmimanesh, G Kleywegt, G Kleywegt, H Arima, H-J Hsu, Helena F. Florindo, HJC Berendsen, HM Berman, I Jatczak-Pawlik, I Tanis, JC Phillips, K Öztürk, KT Al-Jamal, LF Pinto, LF Pinto, Liana C. Silva, M Bello, M Kalomiraki, M Zloh, Mire Zloh, MK Mishra, N Li, N Martinho, Nuno Martinho, R Alberto, S Ahmed, S Dong, S Ghosh, S Javor, S Raut, S Svenson, SH Kim, Steve Brocchini, Teresa Barata, TS Barata, TS Barata, TS Barata, TTC Nguyen, V Maingi, X Cai, Y Liu   +52 more
core   +3 more sources

Chemistry of Secondary Metabolites (Production, Properties, Biological Activity, etc.): Solubility Study of the Interaction between Pamam G-3 Dendrimer and 5 Fluorouracil in Aqueous Solution

International Journal of Secondary Metabolite, 2014
Poly(amidoamine) dendrimers (PAMAM) are polymeric macromolecules that can find their use as carriers of small ligand molecules such as cosmetics and drugs.
B. PALECZ, A. BUCZKOWSKI, L. B. ZAVODNIK   +2 more
doaj   +2 more sources

Dendrimers for Drug Delivery

Molecules, 2018
Dendrimers have come a long way in the last 25 years since their inception. Originally created as a wonder molecule of chemistry, dendrimer is now in the fourth class of polymers. Dr.
Abhay Singh Chauhan
doaj   +1 more source

Curcumin Loaded Dendrimers Specifically Reduce Viability of Glioblastoma Cell Lines

Molecules, 2021
Glioblastoma (GB) is a deadly and aggressive cancer of the CNS. Even with extensive resection and chemoradiotherapy, patient survival is still only 15 months. To maintain growth and proliferation, cancer cells require a high oxidative state.
John Gallien, Bhairavi Srinageshwar, Kellie Gallo, Gretchen Holtgrefe, Sindhuja Koneru, Paulina Sequeiros Otero, Catalina Alvarez Bueno, Jamie Mosher, Alison Roh, D. Stave Kohtz, Douglas Swanson, Ajit Sharma, Gary Dunbar, Julien Rossignol   +13 more
doaj   +1 more source

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

Advanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali, Sharat Chandra Barman, Isobel Steer, Aya H. Alshareef, Dana Alsulaiman   +4 more
wiley   +1 more source