Results 41 to 50 of about 41,761 (267)

Superelastic and pH-Responsive Degradable Dendrimer Cryogels Prepared by Cryo-aza-Michael Addition Reaction [PDF]

, 2018
Dendrimers exhibit super atomistic features by virtue of their well-defined discrete quantized nanoscale structures. Here, we show that hyperbranched amine-terminated polyamidoamine (PAMAM) dendrimer G4.0 reacts with linear polyethylene glycol (PEG ...
Wang, Juan, Yang, Hu
core   +3 more sources

Structure of Carbon Nanotube-dendrimer composite

, 2012
Using all atomistic molecular dynamics (MD) simulations we report the microscopic picture of the nanotube-dendrimer complex for PAMAM dendrimer of generation 2 to 4 and carbon nanotube of chirality (6,5).
Maiti, Prabal K, Pramanik, Debabrata, Sood, A. K., Vasumathi, V.   +3 more
core   +1 more source

Kajian Dendrimer (Poly)Amidoamine (Pamam) Generasi 4 Sebagai Template Dalam Pembentukan Nanopartikel Secara In Silico

Journal of Tropical Pharmacy and Chemistry, 2017
Dendrimers are a class of highly branched synthetic polymers that has spherical form consist of three components: core, branch and terminal functional groups. One of dendrimer that has been commercialized is (Poly)amidoamine (PAMAM).
Yurika Sastyarina, Zuhrotun Nafisah, Muhammad Yusuf, Martalena Ramli, Abdul Mutalib, Ukun Soedjanaatmadja   +5 more
doaj   +1 more source

Condensation transition in DNA-polyaminoamide dendrimer fibers studied using optical tweezers [PDF]

, 2006
When mixed together, DNA and polyaminoamide (PAMAM) dendrimers form fibers that condense into a compact structure. We use optical tweezers to pull condensed fibers and investigate the decondensation transition by measuring force-extension curves (FECs ...
C. Bustamante, C. G. Baumann, F. Ritort, G. I. Bell, J. F. Marko, S. B. Smith, S. Mihardja   +6 more
core   +2 more sources

An Available Strategy for Nasal Brain Transport of Nanocomposite Based on PAMAM Dendrimers via In Situ Gel

Nanomaterials, 2019
Polyamidoamine (PAMAM) dendrimers are efficient drug carriers. The presence of a physiological pathway for nasal brain transport provides a potential path for direct brain-targeted delivery of dendrimer nanocomposites. In this study, we synthesized PAMAM
Huichao Xie, Lingjun Li, Yue Sun, Yuzhen Wang, Shuang Gao, Yuan Tian, Xuemei Ma, Chengcheng Guo, Fumin Bo, Li Zhang   +9 more
doaj   +1 more source

On-Demand Bioadhesive Dendrimers with Reduced Cytotoxicity

Molecules, 2018
Tissue adhesives based on polyamidoamine (PAMAM) dendrimer, grafted with UV-sensitive aryldiazirine (PAMAM-g-diazirine) are promising new candidates for light active adhesion on soft tissues.
Feng Gao, Ivan Djordjevic, Oleksandr Pokholenko, Haobo Zhang, Junying Zhang, Terry W. J. Steele   +5 more
doaj   +1 more source

Molecular modeling to study dendrimers for biomedical applications [PDF]

, 2014
© 2014 by the authors; licensee MDPI; Basel; Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
Buhleier, Carbone, Florida, Helena Florindo, Hess, Klajnert, Liana Silva, Mire Zloh, Nuno Martinho, Radhika, Shaunak, Shcharbin, Steve Brocchini, Teresa Barata, Tomalia, Šebestík   +15 more
core   +4 more sources

Thermodynamic Interaction between PAMAM G4-NH2, G4-OH, G3.5-COONa Dendrimers and Gemcitabine in Water Sotutions

International Journal of Secondary Metabolite, 2016
The thermodynamics of complex formation of polyamideamine dendrimers: cationic PAMAM G4-NH2, neutral PAMAM G4-OH and anionic PAMAM G3.5-COONa with gemcitabine hydrochloride, an antitumor drug, in water at a temperature of 250C was studied.
Bartlomiej Palecz, Adam Buczkowski, Henryk Piekarski, Özge Kılınçarslan   +3 more
doaj   +3 more sources

Dendrimer-based selective autophagy-induction rescues ΔF508-CFTR and inhibits Pseudomonas aeruginosa infection in cystic fibrosis.

PLoS ONE, 2017
BackgroundCystic Fibrosis (CF) is a genetic disorder caused by mutation(s) in the CF-transmembrane conductance regulator (Cftr) gene. The most common mutation, ΔF508, leads to accumulation of defective-CFTR protein in aggresome-bodies.
Scott Mackenzie Brockman, Manish Bodas, David Silverberg, Ajit Sharma, Neeraj Vij   +4 more
doaj   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source