Results 1 to 10 of about 335 (89)

Conjugation of Gentamicin to Polyamidoamine Dendrimers Improved Anti-bacterial Properties against Pseudomonas aeruginosa [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2021
Purpose: This study aimed to design gentamicin-conjugated poly (amidoamine) (PAMAM) dendrimers to increase the therapeutic efficiency of gentamicin against Pseudomonas aeruginosa.
Hamed Sheykhloo   +4 more
doaj   +1 more source

PAMAM-Calix-Dendrimers: Second Generation Synthesis, Fluorescent Properties and Catecholamines Binding

open access: yesPharmaceutics, 2022
A convenient method for the synthesis of the second generation of PAMAM dendrimers based on a p-tert-butylthiacalix[4]arene core in cone, partial cone and 1,3-alternate conformations was developed.
Olga Mostovaya   +7 more
doaj   +1 more source

Paramagnetic NMR investigation of dendrimer-based host-guest interactions. [PDF]

open access: yesPLoS ONE, 2013
In this study, the host-guest behavior of poly(amidoamine) (PAMAM) dendrimers bearing amine, hydroxyl, or carboxylate surface functionalities were investigated by paramagnetic NMR studies.
Fei Wang, Naimin Shao, Yiyun Cheng
doaj   +1 more source

Design and synthesis of biodegradable nonconjugated SSPAMAM dendrimers with unexpected Deep-red/NIR emission and cell membrane targeting ability for biological imaging

open access: yesMaterials & Design, 2022
Fluorescent non-conjugated polymers without any π-aromatic building blocks are of great significance in biological applications due to low cytotoxicity and good biocompatibility.
Xiao-lin Guan   +9 more
doaj   +1 more source

Nanoparticle Effects on Human Platelets in Vitro: A Comparison between PAMAM and Triazine Dendrimers

open access: yesMolecules, 2016
Triazine and PAMAM dendrimers of similar size and number of cationic surface groups were compared for their ability to promote platelet aggregation. Triazine dendrimers (G3, G5 and G7) varied in molecular weight from 8 kDa–130 kDa and in surface groups ...
Alan E. Enciso   +5 more
doaj   +1 more source

Dendrimers bind antioxidant polyphenols and cisplatin drug.

open access: yesPLoS ONE, 2012
Synthetic polymers of a specific shape and size play major role in drug delivery systems. Dendrimers are unique synthetic macromolecules of nanometer dimensions with a highly branched structure and globular shape with potential applications in gene and ...
Amine Abderrezak   +4 more
doaj   +1 more source

Analysis of Biotinylated Generation 4 Poly(amidoamine) (PAMAM) Dendrimer Distribution in the Rat Brain and Toxicity in a Cellular Model of the Blood-Brain Barrier

open access: yesMolecules, 2013
Dendrimers are highly customizable nanopolymers with qualities that make them ideal for drug delivery. The high binding affinity of biotin/avidin provides a useful approach to fluorescently label synthesized dendrimer-conjugates in cells and tissues.
Heather A. Bullen   +10 more
doaj   +1 more source

The effect of prolonged incubation time on the interaction between PAMAM dendrimers and iminodiacetic acid derivatives

open access: yesCurrent Issues in Pharmacy and Medical Sciences, 2012
Dendrimers, highly branched spherical polymers, are known for their ability to act as solubility enhancers of various types of drugs. In the present study, we investigated the potential of poly(amidoamine) (PAMAM) dendrimers G1-G4 in concentration from ...
Magdalena Markowicz   +2 more
doaj   +1 more source

Use of poly (amidoamine) dendrimer for dentinal tubule occlusion: a preliminary study. [PDF]

open access: yesPLoS ONE, 2015
The occlusion of dentinal tubules is an effective method to alleviate the symptoms caused by dentin hypersensitivity, a significant health problem in dentistry and daily life.
Tianda Wang   +3 more
doaj   +1 more source

Dataset of 1H-nuclear magnetic resonance and mass spectra of surface modified Poly(amidoamine) dendrimers with LFC131 peptide

open access: yesData in Brief, 2021
In the present article, we describe the spectroscopic data of poly(amido)amine dendrimers generation 5.0 (G5 PAMAM) conjugated with LFC131 peptide at different specified reaction points.
Chuda Chittasupho   +2 more
doaj   +1 more source

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