Results 21 to 30 of about 23,036 (202)
International Journal of Nanomedicine, 2014 Joseph B Pryor,1 Bryan J Harper,1 Stacey L Harper1,21Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA; 2School of Chemical, Biological, and Environmental Engineering, Oregon State University, Corvallis, OR,
Pryor JB, Harper BJ, Harper SL
doaj +1 more source
Engineering PAMAM dendrimers for optimized drug delivery [PDF]
Nano TrendsDendrimers, first introduced by Fritz Vögtle in 1978, have emerged as promising nanocarriers for drug delivery due to their unique branched architecture, large internal cavities, and numerous surface amine groups.
Amin Aleebrahim Dehkordi +3 more
doaj +2 more sources
Dendrimers in gene delivery [PDF]
, 2005 Dendrimers have unique molecular architectures and properties that make them attractive materials for the development of nanomedicines. Key properties such as defined architecture and a high ratio of multivalent surface moieties to molecular volume also ...
Dufès, Christine +2 more
core +4 more sources
Cationic PAMAM Dendrimers Disrupt Key Platelet Functions
, 2016 Poly(amidoamine) (PAMAM) dendrimers have been proposed for a variety of biomedical applications and are increasingly studied as model nanomaterials for such use. The dendritic structure features both modular synthetic control of molecular size and shape
Robert A. Campbell (197299) +12 more
core +6 more sources
Development of advanced nanosized molecularly inprinted polymers via surface-initiatied 'living' radical polymerisation [PDF]
, 2012 Surface-initiated photo-iniferter mediated controlled polymerisation was used as a technique for the development of advanced and smart materials. Molecularly imprinted polymer (MIP) shell nanoparticles (NPs) were synthesised in this way from PAMAM ...
Ivanova-Mitseva, Petya K.
core +7 more sources
PAMAM dendrimers for the delivery of the antibacterial Triclosan [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2008 Many oral care products incorporate an antibacterial compound to prevent the formation of dental plaque which predisposes teeth to dental caries or periodontal disease. Triclosan (TCN) is a commonly used antiplaque agent in toothpastes. Strategies to increase the delivery efficiency of antibacterials using formulation aids such as polyamidoamine (PAMAM)
Gardiner, Jonathan; id_orcid 0000-0003-1827-6817 +5 more
openaire +3 more sources
New Dendrimers: Synthesis and Characterization of POPAM−PAMAM Hybrid Dendrimers [PDF]
Macromolecules, 2008 Recently developed multifunctional cancer therapeutic nano-device production is based on poly(amidoamine) PAMAM generation 5 (G5) dendrimer as a carrier 1-5. Scale up synthesis of this nano-device is limited because of long reaction sequence (12 reaction steps) and long and not easy work up of the products after each reaction step.
István J, Majoros +3 more
openaire +2 more sources
PAMAM dendrimer - cell membrane interactions
Advances in Colloid and Interface Science, 2018 PAMAM dendrimers have been conjectured for a wide range of biomedical applications due to their tuneable physicochemical properties. However, their application has been hindered by uncertainties in their cytotoxicity, which is influenced by dendrimer generation (i.e.
Fox, Laura J +2 more
openaire +4 more sources
Nucleic Acid Carriers Based on Precise Polymer Conjugates [PDF]
, 2011 Polymer polydispersity, random conjugation of functional groups, and poorly understood structure–activity relationships have constantly hampered progress in the development of nucleic acid carriers.
Christina Troiber +3 more
core +1 more source
Biogenic and synthetic polyamines bind cationic dendrimers.
PLoS ONE, 2012 Biogenic polyamines are essential for cell growth and differentiation, while polyamine analogues exert antitumor activity in multiple experimental model systems, including breast and lung cancer.
Jean-Sebastian Mandeville +3 more
doaj +1 more source