Results 21 to 30 of about 42,023 (262)
Pharmaceutics, 2022 A convenient method for the synthesis of the second generation of PAMAM dendrimers based on a p-tert-butylthiacalix[4]arene core in cone, partial cone and 1,3-alternate conformations was developed.
Olga Mostovaya +7 more
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Inverse Polyamidoamine (i‐PAMAM) Dendrimer Antimicrobials
Helvetica Chimica Acta, 2023 AbstractHere we redesigned the branches of polyamidoamine (PAMAM) dendrimers by moving the amide carbonyl group on the other side of the amide nitrogen atom, transforming the β‐alaninyl‐amidoethylamine branch, which easily undergoes retro‐Michael reactions and renders PAMAMs intrinsically unstable, into a more stable glycyl‐amidopropylamine branch. The
Bonvin, Etienne, Reymond, Jean-Louis
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Materials Science and Engineering C: Materials for Biological Applications, 2021 Rheumatoid arthritis is a chronic autoimmune disease characterised by joint synovial inflammation, along with cartilage and bone tissue destruction. Dendrimers can offer new opportunities as drug delivery systems of molecules of interest. Herein we aimed
I. Oliveira +7 more
semanticscholar +1 more source
Intrinsic Fluorescence of PAMAM Dendrimers-Quenching Studies. [PDF]
Polymers (Basel), 2018 Intrinsic, non-traditional fluorescence of polyamidoamine (PAMAM) dendrimers that do not possess classical fluorophores has been attracting considerable interest for the last decade. Many hypotheses regarding the source of the fluorescence have appeared, but some of them are still disputable.
Konopka M +2 more
europepmc +4 more sources
Materials & Design, 2022 Fluorescent non-conjugated polymers without any π-aromatic building blocks are of great significance in biological applications due to low cytotoxicity and good biocompatibility.
Xiao-lin Guan +9 more
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Paramagnetic NMR investigation of dendrimer-based host-guest interactions. [PDF]
PLoS ONE, 2013 In this study, the host-guest behavior of poly(amidoamine) (PAMAM) dendrimers bearing amine, hydroxyl, or carboxylate surface functionalities were investigated by paramagnetic NMR studies.
Fei Wang, Naimin Shao, Yiyun Cheng
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New Dendrimers: Synthesis and Characterization of POPAM−PAMAM Hybrid Dendrimers [PDF]
Macromolecules, 2008 Recently developed multifunctional cancer therapeutic nano-device production is based on poly(amidoamine) PAMAM generation 5 (G5) dendrimer as a carrier 1-5. Scale up synthesis of this nano-device is limited because of long reaction sequence (12 reaction steps) and long and not easy work up of the products after each reaction step.
István J, Majoros +3 more
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Effect of Terminal Groups of Dendrimers in the Complexation with Antisense Oligonucleotides and Cell Uptake [PDF]
, 2016 Indexación: Web of Science.Poly(amidoamine) dendrimers are the most recognized class of dendrimer. Amino-terminated (PAMAM-NH2) and hydroxyl-terminated (PAMAM-OH) dendrimers of generation 4 are widely used, since they are commercially available.
Araya-Durán, Ingrid +10 more
core +1 more source
PAMAM dendrimer - cell membrane interactions
Advances in Colloid and Interface Science, 2018 PAMAM dendrimers have been conjectured for a wide range of biomedical applications due to their tuneable physicochemical properties. However, their application has been hindered by uncertainties in their cytotoxicity, which is influenced by dendrimer generation (i.e.
Fox, Laura J +2 more
openaire +4 more sources
Nanoparticle Effects on Human Platelets in Vitro: A Comparison between PAMAM and Triazine Dendrimers
Molecules, 2016 Triazine and PAMAM dendrimers of similar size and number of cationic surface groups were compared for their ability to promote platelet aggregation. Triazine dendrimers (G3, G5 and G7) varied in molecular weight from 8 kDa–130 kDa and in surface groups ...
Alan E. Enciso +5 more
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