Results 31 to 40 of about 42,023 (262)

Dendrimers in gene delivery [PDF]

open access: yes, 2005
Dendrimers have unique molecular architectures and properties that make them attractive materials for the development of nanomedicines. Key properties such as defined architecture and a high ratio of multivalent surface moieties to molecular volume also ...
Dufès, Christine   +2 more
core   +1 more source

Dendritic glycopolymers based on dendritic polyamine scaffolds: view on their synthetic approaches, characteristics and potential for biomedical applications [PDF]

open access: yes, 2014
In this review we highlight the potential for biomedical applications of dendritic glycopolymers based on polyamine scaffolds. The complex interplay of the molecular characteristics of the dendritic architectures and their specific interactions with ...
Abbott   +278 more
core   +2 more sources

Dendrimers bind antioxidant polyphenols and cisplatin drug.

open access: yesPLoS ONE, 2012
Synthetic polymers of a specific shape and size play major role in drug delivery systems. Dendrimers are unique synthetic macromolecules of nanometer dimensions with a highly branched structure and globular shape with potential applications in gene and ...
Amine Abderrezak   +4 more
doaj   +1 more source

Starburst pamam dendrimers: Synthetic approaches, surface modifications, and biomedical applications

open access: yes, 2020
Dendrimers are having novel three dimensional, synthetic hyperbranched, nano-polymeric structure. Among all of the dendrimers, Poly-amidoamine (PAMAM) dendrimer are used enormously applying materials in supramolecular chemistry. This review described the
R. Kharwade   +4 more
semanticscholar   +1 more source

G4.5 Pamam Dendrimer-Risperidone: Biodistribution and Behavioral Changes in In Vivo Model [PDF]

open access: yes, 2013
Dendritic polymers are considered as emerging and outstanding carriers as modern medicinal systems due to their derivatisable branched architecture and possibility to modify them in numerous ways.
Alonso, Silvia del Valle   +6 more
core   +2 more sources

Polyethylene glycolated PAMAM dendrimers-Efavirenz conjugates

open access: yesInternational Journal of Pharmaceutical Investigation, 2014
The preparation of novel PEGylated PAMAM (poly-amidoamine) dendrimers for delivery of anti-HIV drug Efavirenz is reported.About 5.0 G PAMAM dendrimers are prepared by ethylene diamine core via Michael addition by divergent method. PEGylation is done by polyethylene glycol 600 using epichlorhydrin as linker.
Pyreddy, Suneela   +2 more
openaire   +3 more sources

Analysis of Biotinylated Generation 4 Poly(amidoamine) (PAMAM) Dendrimer Distribution in the Rat Brain and Toxicity in a Cellular Model of the Blood-Brain Barrier

open access: yesMolecules, 2013
Dendrimers are highly customizable nanopolymers with qualities that make them ideal for drug delivery. The high binding affinity of biotin/avidin provides a useful approach to fluorescently label synthesized dendrimer-conjugates in cells and tissues.
Heather A. Bullen   +10 more
doaj   +1 more source

Use of poly (amidoamine) dendrimer for dentinal tubule occlusion: a preliminary study. [PDF]

open access: yesPLoS ONE, 2015
The occlusion of dentinal tubules is an effective method to alleviate the symptoms caused by dentin hypersensitivity, a significant health problem in dentistry and daily life.
Tianda Wang   +3 more
doaj   +1 more source

Dataset of 1H-nuclear magnetic resonance and mass spectra of surface modified Poly(amidoamine) dendrimers with LFC131 peptide

open access: yesData in Brief, 2021
In the present article, we describe the spectroscopic data of poly(amido)amine dendrimers generation 5.0 (G5 PAMAM) conjugated with LFC131 peptide at different specified reaction points.
Chuda Chittasupho   +2 more
doaj   +1 more source

Structure of polyamidoamide dendrimers up to limiting generations : a mesoscale description [PDF]

open access: yes, 2009
The polyamidoamide (PAMAM) class of dendrimers was one of the first dendrimers synthesized by Tomalia and co-workers at Dow. Since its discovery the PAMAMs have stimulated many discussions on the structure and dynamics of such hyperbranched polymers ...
Goddard, William A., III   +3 more
core   +1 more source

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