Results 31 to 40 of about 23,036 (202)
Which Dendrimer to Attain the Desired Properties? Focus on Phosphorhydrazone Dendrimers
Molecules, 2018 Among the six Critical Nanoscale Design Parameters (CNDPs) proposed by Prof. Donald A. Tomalia, this review illustrates the influence of the sixth one, which concerns the elemental composition, on the properties of dendrimers.
Anne-Marie Caminade, Jean-Pierre Majoral
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Nanomaterials, 2021 Gene therapy is used to correct or compensate for diseases caused by gene defects and abnormalities. Improving the transfection efficiency and reducing the toxicity of gene carriers are the keys to gene therapy. Similar to a typical cationic gene carrier—
Yanzhen Sun +3 more
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Best Practices for Purification and Characterization of PAMAM Dendrimer [PDF]
Macromolecules, 2012 Poly(amidoamine) (PAMAM) dendrimer are branched polymers with low degrees of heterogeneity. Current synthesis methods, however, result in substantial batch variability. We present our optimized procedure for post-synthesis (and post-market) purification of a generation 5 PAMAM dendrimer by membrane dialysis and demonstrate its effectiveness and ...
Douglas G, Mullen +5 more
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Molecules, 2013 Erythromycin (EM) and tobramycin (TOB) are well-known and widely used antibiotics, belonging to different therapeutic groups: macrolide and aminoglycoside, respectively.
Elzbieta Anna Tryniszewska +4 more
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Molecules, 2018 The polyamidoamine (PAMAM) dendrimer is a highly efficient absorption promoter. In the present study, we studied the absorption-enhancing effects and the mechanism of PAMAM dendrimers with generation 0 to generation 3 (G0–G3) and concentrations (0 ...
Juan Lu +9 more
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Molecules, 2018 Dendrimers have come a long way in the last 25 years since their inception. Originally created as a wonder molecule of chemistry, dendrimer is now in the fourth class of polymers. Dr.
Abhay Singh Chauhan
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Identification of polyamidoamine dendrimers (PAMAM-NH2) by ESI-Q-TOF method
Current Issues in Pharmacy and Medical Sciences, 2012 The method of identification of poly(amidoamine) dendrimers (PAMAM-NH2) G1.0, G2.0 and G3.0 generation with the use of high resolution mass spectrometry and hybrid quadrupole-time-of-flight analyzer with electrospray ionization (ESI-Q-TOF) was developed.
Robert Skibiński +3 more
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Synthesis of small PAMAM-dendrimers with Well-defined Structural Diversity. [PDF]
In this paper, we present for the first time a general scalable, synthetic scheme that allows control over the position and number of different surface groups on PAMAM-dendrimers.
Søren, Leth Mejlsøe +2 more
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Next MaterialsDendrimers, a polymeric macromolecule, have been explored for improving the solubility of water-insoluble drugs, and PAMAM is the most explored dendrimer in nanomedicine. But amine-terminated PAMAM dendrimers confer toxicity to healthy cells.
Divya Bharti Rai +4 more
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Biodegradable and Biocompatible Functional Polymers for Biomedical Applications
Advanced Functional Materials, EarlyView.Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han +5 more
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