Results 51 to 60 of about 23,036 (202)
Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma
Advanced Science, EarlyView.This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert +8 more
wiley +1 more source
Polyethylene glycolated PAMAM dendrimers-Efavirenz conjugates
International Journal of Pharmaceutical Investigation, 2014 The preparation of novel PEGylated PAMAM (poly-amidoamine) dendrimers for delivery of anti-HIV drug Efavirenz is reported.About 5.0 G PAMAM dendrimers are prepared by ethylene diamine core via Michael addition by divergent method. PEGylation is done by polyethylene glycol 600 using epichlorhydrin as linker.
Pyreddy, Suneela +2 more
openaire +3 more sources
Advances in Aptamer Drug Delivery Systems for Treatment of Glioblastoma
Advanced Science, EarlyView.Aptamers have remarkable recognition capacity which is suitable for assisting drug delivery for GB. This review demonstrates that aptamers have great potential as targeted therapeutic carriers, conjugated to various therapeutic carriers, using a range of conjugation strategies and chemistries.
Alexandra R. Paul +4 more
wiley +1 more source
Interaction of PAMAM dendrimers with the human stratum corneum [PDF]
, 2023 Charles University, Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Technology Supervisor: PharmDr. Anna Paraskevopoulou, Ph.D. Author: Kateřina Žofková Title of the thesis: Interaction of PAMAM dendrimers with human stratum corneum ...
Žofková, Kateřina
core +1 more source
Advanced Science, EarlyView.AI‐enabled de novo design of a TREM1 binder, integrated into a BBB‐crossing and macrophage‐targeted nanoplatform, enables TREM1 degradation and attenuates neuroinflammation, thereby promoting neuroprotection and tissue repair after traumatic brain injury. ABSTRACT Secondary neuroinflammation drives progressive damage after traumatic brain injury (TBI),
Yimin Huang +19 more
wiley +1 more source
Synthesis of PAMAM-Poloxamer Dendrimers and in vitro Test as a Drug Carrier
工程科学与技术, 2011 :Polymeric drug delivery systems are used to improve aqueous solubility and photostability. Camptothecin (CPT) is a plant alkaloid that is practically insoluble in water and photosensitive.
Ma Li-fang, 王宇飞, 郭丽
doaj
BMEMat, EarlyView.A glycosylated dendrimer nanoamplifier hijacks DNA damage‐immune crosstalk for enhanced radio‐immunotherapy of glioblastoma. The responsive release of demethylcantharidin simultaneously blocks repair‐mediated resistance by inhibiting DNA repair and overcomes adaptive immune resistance.
Cong Song +10 more
wiley +1 more source
Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality
BMEMat, EarlyView.Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim +9 more
wiley +1 more source
Synthesis and modification of pamam dendrimers as histone replacement molecules
, 2009 The primary objective of this work was to synthesise and structurally modify a series of PAMAM dendrimers with a view to investigating and controlling their complexation with, and compaction of, DNA.
Jenkins, Alan
core +1 more source
Journal of Saudi Chemical Society, 2015 In this study, poly(amidoamine) (PAMAM) G-2 dendrimer was used for jute yarn. Fourier transform infrared spectroscopy (FT-IR) revealed that all carbonyl groups of jute fibers reacted with amino groups of polyamidoamine dendrimers.
Ali Akbar Zolriasatein +3 more
doaj +1 more source