Results 51 to 60 of about 36,882 (246)

Dendrimers for Drug Delivery

Molecules, 2018
Dendrimers have come a long way in the last 25 years since their inception. Originally created as a wonder molecule of chemistry, dendrimer is now in the fourth class of polymers. Dr.
Abhay Singh Chauhan
doaj   +1 more source

Interaction of PAMAM dendrimers with the human stratum corneum [PDF]

, 2023
Charles University, Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Technology Supervisor: PharmDr. Anna Paraskevopoulou, Ph.D. Author: Kateřina Žofková Title of the thesis: Interaction of PAMAM dendrimers with human stratum corneum ...
Žofková, Kateřina
core   +1 more source

Effect of Mannose Targeting of Hydroxyl PAMAM Dendrimers on Cellular and Organ Biodistribution in a Neonatal Brain Injury Model

Journal of Controlled Release, 2018
&NA; Neurotherapeutics for the treatment of central nervous system (CNS) disorders must overcome challenges relating to the blood‐brain barrier (BBB), brain tissue penetration, and the targeting of specific cells.
Anjali Sharma, Joshua E. Porterfield, Elizabeth S. Smith, Rishi Sharma, S. Kannan, R. Kannan   +5 more
semanticscholar   +1 more source

PAMAM dendrimers as a carbamazepine delivery system for neurodegenerative diseases: A biophysical and nanotoxicological characterization

International journal of pharmaceutics, 2018
Graphical abstract Figure. No Caption available. HighlightsDG4.0 and DG4.5 encapsulated around of 20 molecules of CBZ per dendrimer.DG4.0‐CBZ and DG4.5‐CBZ were stable for 90 days and resistant to lyophilization.Both DG4.0‐CBZ and DG4.5‐CBZ complexes ...
D. E. Igartúa, C. Martinez, Facundo C. Temprana, S. Alonso, J. M. Prieto   +4 more
semanticscholar   +1 more source

PAMAM-Based Dendrimers with Different Alkyl Chains Self-Assemble on Silica Surfaces: Controllable Layer Structure and Molecular Aggregation

, 2018
Amphiphilic poly­(amidoamine) (PAMAM) dendrimers are a well-known dendritic family due to their remarkable ability to self-assemble on solid surface. However, the relationship between molecular conformation (or adsorption kinetics) of a self-assembled ...
Ting Chen (15205), Donghong Guo (3228261), Minghui Zhang (298745), Wei Zhang (405), Jinben Wang (1361514), Fanghui Liu (1361523), Xu Wu (318848), Qingfeng Hou (1753471), Hui Yang (91136), Shujuan Wang (30858)   +9 more
core   +1 more source

Designing of fucosylated dendrimers as a biocompatible carrier for the targeted delivery of chrysin to human lung cancer cells

Next Materials
Dendrimers, a polymeric macromolecule, have been explored for improving the solubility of water-insoluble drugs, and PAMAM is the most explored dendrimer in nanomedicine. But amine-terminated PAMAM dendrimers confer toxicity to healthy cells.
Divya Bharti Rai, Raghu Solanki, Sunita Patel, Deep Pooja, Hitesh Kulhari   +4 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

An Available Strategy for Nasal Brain Transport of Nanocomposite Based on PAMAM Dendrimers via In Situ Gel

Nanomaterials, 2019
Polyamidoamine (PAMAM) dendrimers are efficient drug carriers. The presence of a physiological pathway for nasal brain transport provides a potential path for direct brain-targeted delivery of dendrimer nanocomposites. In this study, we synthesized PAMAM
Huichao Xie, Lingjun Li, Yue Sun, Yuzhen Wang, Shuang Gao, Yuan Tian, Xuemei Ma, Chengcheng Guo, Fumin Bo, Li Zhang   +9 more
semanticscholar   +1 more source

Best Practices for Purification and Characterization of PAMAM Dendrimer [PDF]

Macromolecules, 2012
Poly(amidoamine) (PAMAM) dendrimer are branched polymers with low degrees of heterogeneity. Current synthesis methods, however, result in substantial batch variability. We present our optimized procedure for post-synthesis (and post-market) purification of a generation 5 PAMAM dendrimer by membrane dialysis and demonstrate its effectiveness and ...
Douglas G, Mullen, Ankur, Desai, Mallory A, van Dongen, Mark, Barash, James R, Baker, Mark M, Banaszak Holl   +5 more
openaire   +2 more sources

Modified Surfaces with Nano-Structured Composites of Prussian Blue and Dendrimers. New Materials for Advanced Electrochemical Applications

International Journal of Electrochemical Science, 2011
In this work, the basic theory and the applications of modified surfaces with nano-structured composites of Prussian Blue (PB) and Dendrimers, for the electrochemical detectors and electrocatalyze technologies, currently, represent some of the most ...
Erika Bustos, Luis A. Godínez
doaj   +1 more source