Results 41 to 50 of about 36,882 (246)
Use of poly (amidoamine) dendrimer for dentinal tubule occlusion: a preliminary study. [PDF]
PLoS ONE, 2015 The occlusion of dentinal tubules is an effective method to alleviate the symptoms caused by dentin hypersensitivity, a significant health problem in dentistry and daily life.
Tianda Wang +3 more
doaj +1 more source
Biogenic and synthetic polyamines bind cationic dendrimers.
PLoS ONE, 2012 Biogenic polyamines are essential for cell growth and differentiation, while polyamine analogues exert antitumor activity in multiple experimental model systems, including breast and lung cancer.
Jean-Sebastian Mandeville +3 more
doaj +1 more source
Which Dendrimer to Attain the Desired Properties? Focus on Phosphorhydrazone Dendrimers
Molecules, 2018 Among the six Critical Nanoscale Design Parameters (CNDPs) proposed by Prof. Donald A. Tomalia, this review illustrates the influence of the sixth one, which concerns the elemental composition, on the properties of dendrimers.
Anne-Marie Caminade, Jean-Pierre Majoral
doaj +1 more source
Nanomaterials, 2021 Gene therapy is used to correct or compensate for diseases caused by gene defects and abnormalities. Improving the transfection efficiency and reducing the toxicity of gene carriers are the keys to gene therapy. Similar to a typical cationic gene carrier—
Yanzhen Sun +3 more
doaj +1 more source
Effect of the Generation of PAMAM Dendrimers on the Stabilization of Gold Nanoparticles
Journal of Chemical Information and Modeling, 2020 The behavior of small and intermediate generations of poly(amidoamine) (PAMAM) dendrimers and PAMAM|gold nanocomposites was studied by computational tools and experimental techniques. Molecular dynamics simulations were used to characterize at the atomic
F. Ávila-Salas +4 more
semanticscholar +1 more source
Molecules, 2018 The polyamidoamine (PAMAM) dendrimer is a highly efficient absorption promoter. In the present study, we studied the absorption-enhancing effects and the mechanism of PAMAM dendrimers with generation 0 to generation 3 (G0–G3) and concentrations (0 ...
Juan Lu +9 more
doaj +1 more source
Pharmaceutics, 2018 We present here the development of multifunctional doxorubicin (DOX)-conjugated poly(amidoamine) (PAMAM) dendrimers as a unique platform for pH-responsive drug release and targeted chemotherapy of cancer cells.
Mengen Zhang +8 more
semanticscholar +1 more source
, 2005 Dendrimers have unique molecular architectures and properties that make them attractive materials for the development of nanomedicines. Key properties such as defined architecture and a high ratio of multivalent surface moieties to molecular volume also ...
Dufès, Christine +2 more
core +1 more source
Selective cytotoxicity of PAMAM G5 core-PAMAM G2.5 shell tecto-dendrimers on melanoma cells [PDF]
, 2012 The controlled introduction of covalent linkages between dendrimer building blocks leads to polymers of higher architectural order known as tecto-dendrimers.
Mundiña, Cecilia Beatriz +5 more
core +1 more source
Molecules, 2013 Erythromycin (EM) and tobramycin (TOB) are well-known and widely used antibiotics, belonging to different therapeutic groups: macrolide and aminoglycoside, respectively.
Elzbieta Anna Tryniszewska +4 more
doaj +1 more source