Results 41 to 50 of about 42,023 (262)

Partitioning of Poly(amidoamine) Dendrimers between n-Octanol and Water [PDF]

, 2009
Dendritic nanomaterials are emerging as key building blocks for a variety of nanoscale materials and technologies. Poly(amidoamine) (PAMAM) dendrimers were the first class of dendritic nanomaterials to be commercialized.
Dalleska, Nathan F., Diallo, Mamadou S., Fang, Xiangdong, Giri, Jyotsnendu, Goddard, William A., III, Tang, Yongchun   +5 more
core   +2 more sources

Hydrogel of Ketoconazole and PAMAM Dendrimers: Formulation and Antifungal Activity

Molecules, 2012
Ketoconazole (KET), an imidazole derivative with well-known antifungal properties, is lipophilic and practically insoluble in water, therefore its clinical use has some practical disadvantages.
Elzbieta Tryniszewska, Pawel Tomasz Sacha, Piotr Wieczorek, Magdalena Wroblewska, Katarzyna Winnicka   +4 more
doaj   +1 more source

MicroRNAs delivery into human cells grown on 3D-printed PLA scaffolds coated with a novel fluorescent PAMAM dendrimer for biomedical applications [PDF]

, 2018
Many advanced synthetic, natural, degradable or non-degradable materials have been employed to create scaffolds for cell culture for biomedical or tissue engineering applications. One of the most versatile material is poly-lactide (PLA), commonly used as
Abbaszadeh, Zeinab, D'Oria, Valentina, Dalla Cort, Antonella, Giannicchi, Ilaria, Leoni, Luca, Masotti, Andrea, Mura, Francesco, Paolini, Alessandro   +7 more
core   +2 more sources

Biogenic and synthetic polyamines bind cationic dendrimers.

PLoS ONE, 2012
Biogenic polyamines are essential for cell growth and differentiation, while polyamine analogues exert antitumor activity in multiple experimental model systems, including breast and lung cancer.
Jean-Sebastian Mandeville, Phillipe Bourassa, Thekkumkattil John Thomas, Heidar-Ali Tajmir-Riahi   +3 more
doaj   +1 more source

Molecular Dynamics Study of Charged Dendrimers in Salt-Free Solution: Effect of Counterions [PDF]

, 2005
Polyamidoamine (PAMAM) dendrimers, being protonated under physiological conditions, represent a promising class of nonviral, nano-sized vectors for drug and gene delivery. We performed extensive molecular dynamics simulations of a generic model dendrimer
Andrey A. Gurtovenko, Galperin D. E., Ilpo Vattulainen, Mikko Karttunen, Sergey V. Lyulin   +4 more
core   +3 more sources

Acetylation of PAMAM dendrimers for cellular delivery of siRNA

BMC Biotechnology, 2009
Background The advancement of gene silencing via RNA interference is limited by the lack of effective short interfering RNA (siRNA) delivery vectors. Rational design of polymeric carriers has been complicated by the fact that most chemical modifications ...
Uhrich Kathryn E, Sparks Sarah M, Waite Carolyn L, Roth Charles M   +3 more
doaj   +1 more source

PAMAM-Functionalized Cellulose Nanocrystals with Needle-Like Morphology for Effective Cancer Treatment

Nanomaterials, 2021
Gene therapy is used to correct or compensate for diseases caused by gene defects and abnormalities. Improving the transfection efficiency and reducing the toxicity of gene carriers are the keys to gene therapy. Similar to a typical cationic gene carrier—
Yanzhen Sun, Xiaoli Ma, Xiaodong Jing, Hao Hu   +3 more
doaj   +1 more source

Amine functionalization of cholecyst-derived extracellular matrix with generation 1 PAMAM dendrimer [PDF]

, 2008
This document is the unedited author's version of a Submitted Work that was subsequently accepted for publication in Biomacromolecules, copyright © American Chemical Society after peer review.
Angele P., Babensee J. E., Badylak S., Badylak S. F., Badylak S. F., Badylak S. F., Billiar K., Brody S., Burugapalli K., Buttafoco L., Chandrasekar D., Charulatha V., Chen R. R., Coburn J. C., Curotto E., Domanski D. M., Duan X., Duan X., Duan X., DuBay D. A., Dumas P., Ferrando J. M., Garcia Y., Grinnell F., Henry J. A., Hodde J., Hodde J. P., Ko R., Kochupura P. V., Koizumi N. J., Lee J. M., Lee S. H., Liang H. C., Ma L., Ma Z., Malafaya P. B., McDevitt C. A., McKegney M., Meinert M., Najlah M., Nourse A., Olde Damink L. H., Olde Damink L. H., Osborne C. S., Papagiannaros A., Pek Y. S., Pieper J. S., Saito H., Sokolsky-Papkov M., Tabata Y., Tessmar J. K., Unsworth J. M., van Wachem P. B., van Wachem P. B., van Wachem P. B., Voytik-Harbin S. L., Wissink M. J., Wissink M. J., Wolkers W. F., Yee N., Zhong S., Zilla P.   +61 more
core   +1 more source

Which Dendrimer to Attain the Desired Properties? Focus on Phosphorhydrazone Dendrimers

Molecules, 2018
Among the six Critical Nanoscale Design Parameters (CNDPs) proposed by Prof. Donald A. Tomalia, this review illustrates the influence of the sixth one, which concerns the elemental composition, on the properties of dendrimers.
Anne-Marie Caminade, Jean-Pierre Majoral
doaj   +1 more source

Structure of poly(propyl ether imine) (PETIM) dendrimer from fully atomistic molecular Dynamics Simulation and by Small Angle X-ray scattering [PDF]

, 2006
We study the structure of carboxylic acid terminated neutral poly (propyl ether imine) (PETIM) dendrimer from generation 1 through 6 (G1-G6) in a good solvent (water) by fully atomistic molecular dynamics (MD) simulations.
A. K. Sood, Adronov A., Chandan Jana, G. Jayamurugan, Hearshaw M. A., N. Jayaraman, Prabal K. Maiti, Rajesh Ganapathy, Rapaport D. C.   +8 more
core   +2 more sources