Results 61 to 70 of about 42,023 (262)

Structure of Carbon Nanotube-dendrimer composite

, 2012
Using all atomistic molecular dynamics (MD) simulations we report the microscopic picture of the nanotube-dendrimer complex for PAMAM dendrimer of generation 2 to 4 and carbon nanotube of chirality (6,5).
Maiti, Prabal K, Pramanik, Debabrata, Sood, A. K., Vasumathi, V.   +3 more
core   +1 more source

PAMAM dendrimers as a carbamazepine delivery system for neurodegenerative diseases: A biophysical and nanotoxicological characterization

International journal of pharmaceutics, 2018
Graphical abstract Figure. No Caption available. HighlightsDG4.0 and DG4.5 encapsulated around of 20 molecules of CBZ per dendrimer.DG4.0‐CBZ and DG4.5‐CBZ were stable for 90 days and resistant to lyophilization.Both DG4.0‐CBZ and DG4.5‐CBZ complexes ...
D. E. Igartúa, C. Martinez, Facundo C. Temprana, S. Alonso, J. M. Prieto   +4 more
semanticscholar   +1 more source

Designing of fucosylated dendrimers as a biocompatible carrier for the targeted delivery of chrysin to human lung cancer cells

Next Materials
Dendrimers, a polymeric macromolecule, have been explored for improving the solubility of water-insoluble drugs, and PAMAM is the most explored dendrimer in nanomedicine. But amine-terminated PAMAM dendrimers confer toxicity to healthy cells.
Divya Bharti Rai, Raghu Solanki, Sunita Patel, Deep Pooja, Hitesh Kulhari   +4 more
doaj   +1 more source

Folate-conjugated nanoparticles as a potent therapeutic approach in targeted cancer therapy [PDF]

, 2015
The selective and efficient drug delivery to tumor cells can remarkably improve different cancer therapeutic approaches. There are several nanoparticles (NPs) which can act as a potent drug carrier for cancer therapy.
Bahrami, B., Bakhshaei, P., Ghalamfarsa, G., Hojjat-Farsangi, M., Jadidi-Niaragh, F., Mohammadnia-Afrouzi, M., Sadreddini, S., Yazdani, Y., Yousefi, M.   +8 more
core   +1 more source

Modified Surfaces with Nano-Structured Composites of Prussian Blue and Dendrimers. New Materials for Advanced Electrochemical Applications

International Journal of Electrochemical Science, 2011
In this work, the basic theory and the applications of modified surfaces with nano-structured composites of Prussian Blue (PB) and Dendrimers, for the electrochemical detectors and electrocatalyze technologies, currently, represent some of the most ...
Erika Bustos, Luis A. Godínez
doaj   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

PAMAM dendrimers: blood‐brain barrier transport and neuronal uptake after focal brain ischemia

Journal of Controlled Release, 2018
Drug delivery to the central nervous system is restricted by the blood‐brain barrier (BBB). However, with the onset of stroke, the BBB becomes leaky, providing a window of opportunity to passively target the brain. Here, cationic poly(amido amine) (PAMAM)
S. Santos, Miguel Xavier, D. M. Leite, Débora A Moreira, B. Custódio, M. Torrado, R. Castro, Victoria Leiro, João Rodrigues, H. Tomás, A. P. Pêgo   +10 more
semanticscholar   +1 more source

Interactions of Poly(amidoamine) Dendrimers with Human Serum Albumin: Binding Constants and Mechanisms [PDF]

, 2011
The interactions of nanomaterials with plasma proteins have a significant impact on their in vivo transport and fate in biological fluids. This article discusses the binding of human serum albumin (HSA) to poly(amidoamine) [PAMAM] dendrimers.
Diallo, Mamadou S., Giri, Jyotsnendu, Goddard, William A., III, Kumar, Rajeev, Liu, Yi, Simpson, André J., Woods, Gwen C.   +6 more
core   +1 more source

Nucleic Acid Carriers Based on Precise Polymer Conjugates [PDF]

, 2011
Polymer polydispersity, random conjugation of functional groups, and poorly understood structure–activity relationships have constantly hampered progress in the development of nucleic acid carriers.
Troiber, Christina, Wagner, Ernst
core   +1 more source