Results 81 to 90 of about 36,882 (246)

Visualization of Endosomal Escape of Intracellularly Delivered Protein With Unexpected Photochemical Internalization of Trypan Blue

open access: yesAdvanced Science, Volume 13, Issue 32, 9 June 2026.
TB, a conventional cell viability dye, acts as both a fluorescence modulator (quenching GFP fluorescence upon protein binding and recovering it upon release) and a photosensitizer that triggers endosomal escape via photochemical internalization (PCI) under 590 nm light.
Zhongqi Yao   +4 more
wiley   +1 more source

Inhibition of autophagy protects against PAMAM dendrimers-induced hepatotoxicity

open access: yes, 2016
Toxicity of nanomaterials is one of the biggest challenges in their medicinal applications. Although toxicities of nanomaterials have been widely reported, the exact mechanisms of toxicities are still not well elucidated. Consequently, the exploration of
Xian Zeng (451364)   +7 more
core   +1 more source

Ligand Engineering of Colloidal Nanocrystals for Electrocatalysis

open access: yesAdvanced Energy and Sustainability Research, Volume 7, Issue 6, June 2026.
Surface ligands guide the synthesis of colloidal nanocrystals and influence their working electrocatalytic interfaces. This review summarizes how ligand classes, surface binding and growth, structure regulation, and interfacial ligand states control facet exposure, local environments, and reaction pathways, thereby affecting activity, selectivity, and ...
Ge Yang, Xintong Xu, Qin Li, Dechao Chen
wiley   +1 more source

Synthesis of small PAMAM-dendrimers with Well-defined Structural Diversity.

open access: yes
In this paper, we present for the first time a general scalable, synthetic scheme that allows control over the position and number of different surface groups on PAMAM-dendrimers.
Søren, Leth Mejlsøe   +2 more
core   +1 more source

Use of Polyamidoamine Dendrimers in Brain Diseases

open access: yesMolecules, 2018
Polyamidoamine (PAMAM) dendrimers are one of the smallest and most precise nanomolecules available today, which have promising applications for the treatment of brain diseases. Each aspect of the dendrimer (core, size or generation, size of cavities, and
Maria Florendo   +6 more
doaj   +1 more source

Innovative Drug Delivery Systems for the Treatment of Glaucoma

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
This review aims to provide a comprehensive overview of current topical drug delivery strategies for ocular hypotensive agents in glaucoma therapy. Additionally, it discusses the potential impact of emerging nanotechnological and biomaterial‐based systems in shaping the future of ophthalmic drug delivery, with an emphasis on enhancing efficacy, safety,
Jing Chu   +9 more
wiley   +1 more source

Preferential and Increased Uptake of Hydroxyl-Terminated PAMAM Dendrimers by Activated Microglia in Rabbit Brain Mixed Glial Culture

open access: yesMolecules, 2018
Polyamidoamine (PAMAM) dendrimers are multifunctional nanoparticles with tunable physicochemical features, making them promising candidates for targeted drug delivery in the central nervous system (CNS).
Yossef Alnasser   +7 more
semanticscholar   +1 more source

Bioapplications of poly(amidoamine) (PAMAM) dendrimers in nanomedicine

open access: yesJournal of Nanoparticle Research, 2014
Poly(amidoamine) (PAMAM) dendrimers are a novel class of spherical, well-designed branching polymers with interior cavities and abundant terminal groups on the surface which can form stable complexes with drugs, plasmid DNA, oligonucleotides, and antibodies.
Pourianazar, Negar Taghavi   +2 more
openaire   +2 more sources

Novel Aldehyde-Terminated Dendrimers; Synthesis and Cytotoxicity Assay

open access: yesBioImpacts, 2012
Introduction: Polyamidoamine (PAMAM) dendrimers are a unique family of dendritic polymers with numerous pharmaceutical and biomedical applications. One major problem with these polymers is their cytotoxicity.
Mohammad-Reza Rashidi   +5 more
doaj   +1 more source

Nanoparticle‐Based Strategies to Combat Multidrug‐Resistant Bacteria: Mechanisms, Applications, and Future Perspectives

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
Nanobiotics offer a promising strategy to combat antimicrobial resistance (AMR) and multidrug‐resistant (MDR) bacteria. Nanoparticles overcome traditional resistance mechanisms through unique physicochemical properties and multivalent interactions.
Akmal Zubair   +3 more
wiley   +1 more source

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