Results 101 to 110 of about 42,023 (262)
Use of Polyamidoamine Dendrimers in Brain Diseases
Molecules, 2018 Polyamidoamine (PAMAM) dendrimers are one of the smallest and most precise nanomolecules available today, which have promising applications for the treatment of brain diseases. Each aspect of the dendrimer (core, size or generation, size of cavities, and
Maria Florendo +6 more
doaj +1 more source
ChemPhysChem, Volume 27, Issue 7, 14 April 2026.The development of effective strategies for the detoxification of organophosphorus (OP) nerve agents has evolved from the early mechanistic studies of François Terrier and collaborators, who first elucidated the exceptional nucleophilicity of α‐effect species such as oximes and hydroxamates, to the modern design of supramolecular and material‐based ...
Pedro Rodríguez‐Dafonte
wiley +1 more source
Novel Aldehyde-Terminated Dendrimers; Synthesis and Cytotoxicity Assay
BioImpacts, 2012 Introduction: Polyamidoamine (PAMAM) dendrimers are a unique family of dendritic polymers with numerous pharmaceutical and biomedical applications. One major problem with these polymers is their cytotoxicity.
Mohammad-Reza Rashidi +5 more
doaj +1 more source
Advanced Science, Volume 13, Issue 20, 9 April 2026.Nanozymes, as enzyme‐mimicking nanomaterials, exhibit unique catalytic properties for the treatment of liver diseases. By regulating redox homeostasis, modulating immune responses, and enabling targeted delivery, nanozymes overcome the limitations of natural enzymes.
Xiandi Meng +6 more
wiley +1 more source
, 2017 We investigate key electrostatic features of charged dendrimers at hand of the biomedically important dendritic polyglycerol sulfate (dPGS) macromolecule using multi-scale computer simulations and Zetasizer experiments.
Ballauff, Matthias +4 more
core +1 more source
Biophysical studies in polymer therapeutics: the interactions of anionic and cationic PAMAM dendrimers with lipid monolayers [PDF]
, 2017 Understanding how polymers interact with biological membranes is important for the development of polymer based therapeutics and wider biomedical applications.
Aronson PS +6 more
core +1 more source
Predicting cytotoxicity of PAMAM dendrimers using molecular descriptors
Beilstein Journal of Nanotechnology, 2015 The use of data mining techniques in the field of nanomedicine has been very limited. In this paper we demonstrate that data mining techniques can be used for the development of predictive models of the cytotoxicity of poly(amido amine) (PAMAM ...
David E. Jones +2 more
doaj +1 more source
Journal of Pharmacy & Pharmaceutical Sciences, 2018 Purpose: The antibacterial activity of some antibiotics is specific to either Gram-positive or Gram-negative bacteria. There are different mechanisms behind such insensitivities like inability of antibiotics to permeate through some bacterial membranes,
Azadeh Serri +3 more
doaj +1 more source
Advanced NanoBiomed Research, Volume 6, Issue 4, April 2026.This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari +5 more
wiley +1 more source
Dendrimers and derivatives as a potential therapeutic tool in regenerative medicine strategies : a review [PDF]
, 2010 Since the pioneering work dealing with the synthesis and physicochemical aspects of dendrimers, a predictable and tunable set of compositions for therapeutic, scaffolding and imaging systems has been reported.
Mano, J. F. +4 more
core +1 more source