Advancing the Landscape of RNAi Nanotherapeutics for Ischemic Heart Disease
RNA interference (RNAi) nanomedicine revolutionizes treatment regimens for ischemic heart diseases by enabling tailored, sequence‐anchored gene regulation. This review highlights the recent advances in nanotechnology‐driven RNAi therapeutics for myocardial ischemia and discusses the key design principles that govern efficient delivery, providing ...
Han Gao, Da Pan, Hélder A. Santos
wiley +1 more source
Dendrimer-Encapsulated Nanoparticles: New Synthetic and Characterization Methods and Catalytic Applications [PDF]
In this article we describe the synthesis, characterization, and applications of dendrimer-encapsulated nanoparticles (DENs). These materials are synthesized using a template approach in which metal ions are extracted into the interior of dendrimers and ...
Carino, Emily V. +5 more
core +1 more source
Recent Research Progress on Polyamidoamine-Engineered Hydrogels for Biomedical Applications
Hydrogels are three-dimensional crosslinked functional materials with water-absorbing and swelling properties. Many hydrogels can store a variety of small functional molecules to structurally and functionally mimic the natural extracellular matrix; hence,
Li Liu +4 more
doaj +1 more source
EPR Study of Spin Labeled Brush Polymers in Organic Solvents [PDF]
Spin-labeled polylactide brush polymers were synthesized via ring-opening metathesis polymerization (ROMP), and nitroxide radicals were incorporated at three different locations of brush polymers: the end and the middle of the backbone, and the end of ...
Burts, Alan O. +7 more
core +2 more sources
Drug delivery into the central nervous system (CNS) is challenging due to the blood–brain barrier (BBB) and drug delivery into the brain overcoming the BBB can be achieved using nanoparticles such as dendrimers.
B. Srinageshwar +17 more
semanticscholar +1 more source
Synthesis and Characterization of Poly(Amidoamine) Dendrimers Encapsulated 198Au Nanoparticles [PDF]
Brachytherapy or internal radiotherapy is one of many methods used for treatment of cancer. This modality requires an agent with radionuclides that emits α or β particle with a proper energy.
Kardono, L. B. (L) +9 more
core
Development of tat - conjugated dendrimer for transdermal DNA vaccine delivery [PDF]
PURPOSE: In order to enhance cellular uptake and to facilitate transdermal delivery of DNA vaccine, polyamidoamine (PAMAM) dendrimers conjugated with HIV transactivator of transcription (TAT) was developed.
Bahadoran, Azadeh +4 more
core +2 more sources
Polyamidoamine Dendrimer Conjugates with Cyclodextrins as Novel Carriers for DNA, shRNA and siRNA
Gene, short hairpin RNA (shRNA) and small interfering RNA (siRNA) delivery can be particularly used for the treatment of diseases by the entry of genetic materials mammalian cells either to express new proteins or to suppress the expression of proteins ...
Hidetoshi Arima +2 more
doaj +1 more source
Molecular interactions between dimethoxycurcumin and Pamam dendrimer carriers
Dimethoxycurcumin, a lipophilic analog of curcumin found as a major pigment in the Indian species turmeric (Curcuma longa Linn.), is known to possess significant activity against various cancer cell lines, but its use as an anticancer drug is hindered by its poor water solubility.
Markatou, E. +5 more
openaire +4 more sources
Dendrimer-fullerenol soft-condensed nanoassembly [PDF]
Nanoscale assembly is an area of research that has vast implications for molecular design, sensing, nanofabrication, supramolecular chemistry, catalysis, and environmental remediation.
Bhattacharya, Priyanka +8 more
core +3 more sources

