Results 91 to 100 of about 42,023 (262)
Original Multivalent Gold (III) and Dual Gold(III)-Copper(II) Conjugated Phosphorus Dendrimers as Potent Antitumoral and Antimicrobial Agents [PDF]
, 2017 Original metallophosphorus dendrimers (generation 3, 48 terminal groups) have been prepared via the complexation of phosphorus dendrimers bearing imino-pyridino end groups with Au(III) or with both Au(III) and Cu(II).
Anne-Marie Caminade +11 more
core +3 more sources
Synthesis and characterization of fluorescence poly(amidoamine) dendrimer-based pigments
Scientific Reports, 2022 In this work, we looked at how to make fluorescence hybrid poly(amidoamine) dendrimer (PAMAM) dendrimers using calcozine red 6G and coumarin end groups.
Marzieh Golshan +3 more
doaj +1 more source
Pharmaceutics, 2022 Ruboxistaurin (RBX) is an anti-vascular endothelial growth factor (anti-VEGF) agent that is used in the treatment of diabetic retinopathy and is mainly given intravitreally.
Rehab A. Alshammari +10 more
doaj +1 more source
A Versatile Polymer‐Based In Situ Nanovaccine to Boost Cancer Immunotherapy
Aggregate, Volume 7, Issue 5, May 2026.A polymer‐based in situ nanovaccine (PCR‐NPs) orchestrates a powerful antitumor immune cascade via integrated antigen release, capture, and lymph nodes transport, eliciting potent CD8+ T cell responses that drive significant tumor inhibition and prolonged mice survival in murine tumor models.
Qi‐Song Tong +6 more
wiley +1 more source
PAMAM dendrimer: a pH-controlled nanosponge [PDF]
Canadian Journal of Chemistry, 2017 Using fully atomistic molecular dynamics simulation that are several hundred nanoseconds long, we demonstrate the pH-controlled sponge action of PAMAM dendrimer. We show how at varying pH levels, the PAMAM dendrimer acts as a wet sponge; at neutral or low pH levels, the dendrimer expands noticeably and the interior of the dendrimer opens up to host ...
openaire +1 more source
Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy
Journal of Biomedical Materials Research Part A, Volume 114, Issue 5, May 2026.Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy. Created in BioRender. Jain, E. (2026) https://BioRender.com/x4f9o8g. ABSTRACT Osteoarthritis (OA) is a highly prevalent, disabling, and painful disease of the joints, characterized by progressive cartilage degeneration, synovial fibrosis, and pain.
Era Jain, Paul Nana Kwame Sagoe
wiley +1 more source
PAMAM Dendrimers Undergo pH Responsive Conformational Changes without Swelling [PDF]
, 2009 Atomistic molecular dynamics (MD) simulations of a G4-NH2 PAMAM dendrimer were carried out in aqueous solution using explicit water molecules and counterions (with the Dreiding III force field optimized using quantum mechanics).
Bryantsev, Vyacheslav S. +3 more
core +2 more sources
In Situ Engineered “Cascade‐Amplified” Drug‐Loaded Vesicles for Enhanced Cancer Stem Cell Therapy
Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.ABSTRACT Cancer stem cells (CSCs) characterized by the capacity of self‐renewal and drug resistance, are a major cause of tumour recurrence and metastasis. However, CSCs are mainly localized in the deep and hypoxic regions of the tumour microenvironment that hinder drug penetration.
Tiantian Zhang +11 more
wiley +1 more source
Molecules, 2018 Polyamidoamine (PAMAM) dendrimers are multifunctional nanoparticles with tunable physicochemical features, making them promising candidates for targeted drug delivery in the central nervous system (CNS).
Yossef Alnasser +7 more
semanticscholar +1 more source
Low-generation asymmetric dendrimers exhibit minimal toxicity and effectively complex DNA [PDF]
, 2011 Conventional dendrimers are spherical symmetrically branched polymers ending with active surface functional groups. Polyamidoamine (PAMAM) dendrimers have been widely studied as gene delivery vectors and have proven effective at delivering DNA to cells ...
Parekh, Harendra S. +2 more
core +1 more source