Results 61 to 70 of about 41,761 (267)

Partitioning of Poly(amidoamine) Dendrimers between n-Octanol and Water [PDF]

open access: yes, 2009
Dendritic nanomaterials are emerging as key building blocks for a variety of nanoscale materials and technologies. Poly(amidoamine) (PAMAM) dendrimers were the first class of dendritic nanomaterials to be commercialized.
Dalleska, Nathan F.   +5 more
core   +2 more sources

Visualization of Endosomal Escape of Intracellularly Delivered Protein With Unexpected Photochemical Internalization of Trypan Blue

open access: yesAdvanced Science, EarlyView.
TB, a conventional cell viability dye, acts as both a fluorescence modulator (quenching GFP fluorescence upon protein binding and recovering it upon release) and a photosensitizer that triggers endosomal escape via photochemical internalization (PCI) under 590 nm light.
Zhongqi Yao   +4 more
wiley   +1 more source

Synthesis, Internalization and Visualization of N-(4-Carbomethoxy) Pyrrolidone Terminated PAMAM [G5:G3-TREN] Tecto(dendrimers) in Mammalian Cells

open access: yesMolecules, 2020
Tecto(dendrimers) are well-defined, dendrimer cluster type covalent structures. In this article, we present the synthesis of such a PAMAM [G5:G3-(TREN)]-N-(4-carbomethoxy) pyrrolidone terminated tecto(dendrimer).
Maciej Studzian   +5 more
doaj   +1 more source

Development of an Enzymatic Biosensor Using Glutamate Oxidase on Organic–Inorganic-Structured, Electrospun Nanofiber-Modified Electrodes for Monosodium Glutamate Detection

open access: yesBiosensors, 2023
Herein, dendrimer-modified montmorillonite (Mt)-decorated poly-Ɛ-caprolactone (PCL) and chitosan (CHIT)-based nanofibers were prepared. Mt was modified with a poly(amidoamine) generation 1 (PAMAMG1) dendrimer, and the obtained PAMAMG1–Mt was incorporated
Hamdiye Atilgan   +7 more
doaj   +1 more source

Fluorinated Amphiphilic Dendrimer to Improve PET Imaging of Cancer

open access: yesSmall, EarlyView.
Fluorination of a self‐assembling dendrimer nanosystem reduced liver retention, accelerated renal clearance and improved biodistribution, ultimately enhancing tumor uptake and enabling more sensitive tumor detection by positron emission tomography (PET).
Béatrice Louis   +16 more
wiley   +1 more source

Bolstering cholesteryl ester hydrolysis in liver: A hepatocyte-targeting gene delivery strategy for potential alleviation of atherosclerosis [PDF]

open access: yes, 2017
Current atherosclerosis treatment strategies primarily focus on limiting further cholesteryl esters (CE) accumulation by reducing endogenous synthesis of cholesterol in the liver.
Ghosh, Shobha   +5 more
core   +2 more sources

Dendrimeric Antigens for Passive Mast Cell Activation in the Evaluation of Amoxicillin Allergy

open access: yesAllergy, EarlyView.
DeAns with defined nanoscale structure reveal that conjugate size and determinant density govern IgE‐mediated effector‐cell activation in AX allergy. All DeAn generations bind to sIgE in inhibition immunoassay, but only larger DeAns trigger FcεRI‐dependent responses in mouse MC, huRBL‐2H3, and LUVA cells.
Amene Tesfaye Ayane   +12 more
wiley   +1 more source

Cationic PAMAM Dendrimers Aggressively Initiate Blood Clot Formation [PDF]

open access: yesACS Nano, 2012
Poly(amidoamine) (PAMAM) dendrimers are increasingly studied as model nanoparticles for a variety of biomedical applications, notably in systemic administrations. However, with respect to blood-contacting applications, amine-terminated dendrimers have recently been shown to activate platelets and cause a fatal, disseminated intravascular coagulation ...
Clinton F, Jones   +10 more
openaire   +2 more sources

One-Step Synthesis of Graphene Oxide-Polyamidoamine Dendrimer Nanocomposite Hydrogels by Self-Assembly [PDF]

open access: yes, 2016
Graphene oxide (GO)-polyamidoamine (PAMAM) dendrimer nanocomposite hydrogels were prepared through a one-step synthesis by mixing a GO suspension and a PAMAM solution at varying ratios of GO to PAMAM.
Chen, B., Piao, Y., Wu, T.
core   +2 more sources

Enhanced Competitive Immunomagnetic Beads Assay Assisted with PAMAM-Gold Nanoparticles Multi-Enzyme Probes for Detection of Deoxynivalenol

open access: yesBiosensors, 2023
Contamination of deoxynivalenol (DON) in grains has attracted widespread concern. It is urgently needed to develop a highly sensitive and robust assay for DON high-throughput screening.
Kun Zeng   +6 more
doaj   +1 more source

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