Results 71 to 80 of about 7,965 (226)

Smart Polymer‐Based Drug Delivery Systems for Managing Infective Conjunctivitis: Advances and Future Prospects

Nano Select, Volume 7, Issue 6, June 2026.
The introduction covers the background and significance of conjunctivitis. It continues with a review of etiology, epidemiology, and clinical manifestations. Diagnostic methods are described, followed by discussions on pathophysiology and classification. Current treatment strategies, preventive measures, and therapeutic challenges are analyzed.
Xia Linkang, Marwan Abdelmahmoud Abdelkarim Maki, Saad Tayyab, Sachin Thakur, Pankaj Kumar, Ritu Karwasra, Mahesh Harihar Behare, Nitin Sharma, Wan Hamirul Bahrin Wan Kamal, Oganeswary Kobi, Kushagra Khanna, Mogana Rajagopal   +11 more
wiley   +1 more source

Chemical structures of polyamines and PAMAM-G4 dendrimer.

, 2013
Chemical structures of polyamines and PAMAM-G4 dendrimer.
Heidar-Ali Tajmir-Riahi (178288), Phillipe Bourassa (324862), Thekkumkattil John Thomas (324863), Jean-Sebastian Mandeville (178280)   +3 more
core   +1 more source

PAMAM dendrimers based co-delivery of methotrexate and berberine for targeting of Hela cancer cells

Toxicology Reports
Polyamidoamine dendrimer (PAMAM) is a class of synthetic macromolecular polymers for targeted drug delivery. PAMAM dendrimers are characterized by a pure defined structure, adjustable nanoscale dimensions, mono-dispersity, and versatile surface ...
Hossein Majidzadeh, Mostafa Araj-Khodaei, Ayuob Aghanejad, Maryam Ghaffari, Amir Jafari, Forough Jenanifard, Jafar Ezzati Nazhad Dolatabadi, Hashem Andishmand, Michael R. Hamblin   +8 more
doaj   +1 more source

Effect of methotrexate conjugated PAMAM dendrimers on the viability of MES-SA uterine cancer cells

Journal of Pharmacy and Bioallied Sciences, 2014
The aim of this work was to synthesize methotrexate (MTX)-polyamidoamine (PAMAM) dendritic nanoconjugates and to study their effect on cell viability in uterine sarcoma cells.
Samreen Khatri, Nandita G Das, Sudip K Das   +2 more
doaj   +1 more source

Gold Nanoparticle–Trastuzumab Conjugates for HER2‐Positive Breast Cancer Treatment: Developments in Radionuclide Therapy, Multimodal Imaging, and Combination Strategies

Nano Select, Volume 7, Issue 6, June 2026.
ABSTRACT This work comprehensively examines recent advances in the treatment of human epidermal growth factor receptor 2 (HER2)‐positive breast cancer using trastuzumab‐conjugated gold nanoparticles (AuNPs). By analyzing several pivotal studies, it explores how these nanoplatforms enhance therapeutic specificity and efficacy while minimizing systemic ...
Tara Tarzi, Zhina Pazhouhesh, Danial Heyrati, Amir Mohammad Ghanbari Zarmehri, Ali Es‐haghi, Mohammad Ehsan Taghavizadeh Yazdi   +5 more
wiley   +1 more source

Potential Use of Folate-polyethylene glycol (PEG)-Appended Dendrimer (G3) Conjugate with alpha-Cyclodextrin as DNA Carriers to Tumor Cells

, 2011
We previously reported that polyamidoamine STARBURST dendrimer (generation 3, G3) (dendrimer) conjugate with alpha-cyclodextrin (alpha-CyD) having an average degree of substitution of 2.4 of alpha-CyD (alpha-CDE) provided remarkable aspects as novel ...
Masayo Arizono, Fumitoshi Hirayama, Hidetoshi Arima, Haruna Ikeda, Tomoko Takeuchi, Kaneto Uekama, Taishi Higashi, Ayumi Yoshimitsu, Kenjiro Hattori, Keiichi Motoyama   +9 more
core  

PAMAM dendrimer with 4-carbomethoxypyrrolidone - In vitro assessment of neurotoxicity

, 2015
Cytotoxicity of cationic amino-terminated PAMAM dendrimer and modified PAMAM-pyrrolidone dendrimer was compared. LDH assay and cell visualization technique were employed. Mouse embryonic hippocampal cells (mHippoE-18) were used.
Klajnert-Maculewicz, Barbara, Studzian, Maciej, Christensen, Jørn Bolstad, Janaszewska, Anna, Ficker, Mario, Petersen, Johannes Fabritius   +5 more
core   +1 more source

Fluorinated Amphiphilic Dendrimer to Improve PET Imaging of Cancer

Small, Volume 22, Issue 35, 23 June 2026.
Fluorination of a self‐assembling dendrimer nanosystem reduced liver retention, accelerated renal clearance and improved biodistribution, ultimately enhancing tumor uptake and enabling more sensitive tumor detection by positron emission tomography (PET).
Béatrice Louis, Tom Roussel, Twiany Cruz‐Dubois, Ling Ding, Zhenbin Lyu, Erik Laurini, Jessica Ou, Laure Balasse, Adrien Chabert, Vincent Nail, Ahlem Bouhlel, Françoise Dignat‐George, Florence Gattacceca, Sabrina Pricl, Benjamin Guillet, Ling Peng, Philippe Garrigue   +16 more
wiley   +1 more source

Dendrimers bind antioxidant polyphenols and cisplatin drug.

PLoS ONE, 2012
Synthetic polymers of a specific shape and size play major role in drug delivery systems. Dendrimers are unique synthetic macromolecules of nanometer dimensions with a highly branched structure and globular shape with potential applications in gene and ...
Amine Abderrezak, Philippe Bourassa, Jean-Sebastian Mandeville, Reza Sedaghat-Herati, Heidar-Ali Tajmir-Riahi   +4 more
doaj   +1 more source

Ligand‐specific tuning of CLEC10A signalling strength and dendritic cell responses through engagement of different GalNAc‐containing glycan structures

The FEBS Journal, Volume 293, Issue 11, Page 3187-3210, June 2026.
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs, Remi Hatinguais, Mike de Kok, R. J. Eveline Li, Tesfay M. Godefa, Victor L. J. L. Thijssen, Yvette van Kooyk, Sandra J. van Vliet   +7 more
wiley   +1 more source