Results 71 to 80 of about 5,727 (183)

PAMAM dendrimer derivatives as a potential drug for antithrombotic therapy

European Journal of Medicinal Chemistry, 2013
Platelets are anucleated blood cells that play an important role both in the pathogenesis of atherosclerosis and subsequent thrombosis. Dendrimers have attracted great interest in biomedical applications. However, their interactions with cell compounds and compartments are nonselective, thus causing cytotoxicity and hemotoxicity.
Duran-Lara, Esteban, Guzman, Luis, John, Amalraj, Fuentes, Eduardo, Alarcon, Marcelo, Palomo, Ivan, Santos, Leonardo S.   +6 more
openaire   +4 more sources

In vitro antibacterial activity of poly (amidoamine)-G7 dendrimer

BMC Infectious Diseases, 2017
Background Nano-scale dendrimers are synthetic macromolecules that frequently used in medical and health field. Traditional anibiotics are induce bacterial resistence so there is an urgent need for novel antibacterial drug invention. In the present study
Mitra Gholami, Rashin Mohammadi, Mohsen Arzanlou, Fakhraddin Akbari Dourbash, Ebrahim Kouhsari, Gharib Majidi, Seyed Mohsen Mohseni, Shahram Nazari   +7 more
doaj   +1 more source

Designing of fucosylated dendrimers as a biocompatible carrier for the targeted delivery of chrysin to human lung cancer cells

Next Materials
Dendrimers, a polymeric macromolecule, have been explored for improving the solubility of water-insoluble drugs, and PAMAM is the most explored dendrimer in nanomedicine. But amine-terminated PAMAM dendrimers confer toxicity to healthy cells.
Divya Bharti Rai, Raghu Solanki, Sunita Patel, Deep Pooja, Hitesh Kulhari   +4 more
doaj   +1 more source

Use of Polyamidoamine Dendrimers in Brain Diseases

Molecules, 2018
Polyamidoamine (PAMAM) dendrimers are one of the smallest and most precise nanomolecules available today, which have promising applications for the treatment of brain diseases. Each aspect of the dendrimer (core, size or generation, size of cavities, and
Maria Florendo, Alexander Figacz, Bhairavi Srinageshwar, Ajit Sharma, Douglas Swanson, Gary L. Dunbar, Julien Rossignol   +6 more
doaj   +1 more source

Effect of polyhydroxy-terminated PAMAM dendrimer on dentin matrix metalloproteinases within the hybrid layers. [PDF]

BMC Oral Health, 2023
Luo Y, Si R, He Y, Wang M, Yu Y, Huang X, Huang R, Huang Y, Luo Y, Jin W, Gou Y.   +10 more
europepmc   +1 more source

Preparation of Cu nanocomposites from EDA, DETA, and Jeffamine core PAMAM dendrimers with TRIS and carboxyl surface functional groups

Acta Chimica Slovenica, 2016
This study presents the synthesis and UV-VIS characterization of Cu nanocomposites from (EDA) (E), diethylene triamine (DETA) (D), and Jeffamine® T-403 (P) core PAMAM dendrimers with TRIS and carboxyl surface functional groups.
Ali Serol Ertürk, Mustafa Ulvi Gürbüz, Metin Tülü, Abdürrezzak Emin Bozdoğan   +3 more
doaj   +1 more source

An Evaluation of CXCR4 Targeting with PAMAM Dendrimer Conjugates for Oncologic Applications. [PDF]

Pharmaceutics, 2022
Lesniak WG, Azad BB, Chatterjee S, Lisok A, Pomper MG.   +4 more
europepmc   +1 more source

Electrospun nanofibers of cellulose acetate/metal organic framework-third generation PAMAM dendrimer for the removal of methylene blue from aqueous media. [PDF]

Sci Rep, 2023
Heidari Y, Noroozian E, Maghsoudi S.
europepmc   +1 more source

Synthesis of β-Cyclodextrin-Decorated Dendritic Compounds Based on EDTA Core: A New Class of PAMAM Dendrimer Analogs. [PDF]

Pharmaceutics, 2022
González-Méndez I, Loera-Loera E, Sorroza-Martínez K, Vonlanthen M, Cuétara-Guadarrama F, Bernad-Bernad MJ, Rivera E, Gracia-Mora J.   +7 more
europepmc   +1 more source

Glial Cell Line-Derived Neurotrophic Factor-Loaded CMCht/PAMAM Dendrimer Nanoparticles for Peripheral Nerve Repair. [PDF]

Pharmaceutics, 2022
Escobar A, Carvalho MR, Maia FR, Reis RL, Silva TH, Oliveira JM.   +5 more
europepmc   +1 more source