Results 91 to 100 of about 19,976 (221)
MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.The image illustrates how PROTACs utilize endocytosis, mediated by cell surface proteins, to overcome bioavailability limitations and enable efficient intracellular delivery. ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are promising therapeutic agents for targeted protein degradation via the ubiquitin‐proteasome system; however, their clinical ...
Huahua Chen +3 more
wiley +1 more source
Chemical structures of polyamines and PAMAM-G4 dendrimer.
, 2013 Chemical structures of polyamines and PAMAM-G4 dendrimer.
Heidar-Ali Tajmir-Riahi (178288) +3 more
core +1 more source
In vitro antibacterial activity of poly (amidoamine)-G7 dendrimer
BMC Infectious Diseases, 2017 Background Nano-scale dendrimers are synthetic macromolecules that frequently used in medical and health field. Traditional anibiotics are induce bacterial resistence so there is an urgent need for novel antibacterial drug invention. In the present study
Mitra Gholami +7 more
doaj +1 more source
PAMAM dendrimer derivatives as a potential drug for antithrombotic therapy
European Journal of Medicinal Chemistry, 2013 Platelets are anucleated blood cells that play an important role both in the pathogenesis of atherosclerosis and subsequent thrombosis. Dendrimers have attracted great interest in biomedical applications. However, their interactions with cell compounds and compartments are nonselective, thus causing cytotoxicity and hemotoxicity.
Duran-Lara, Esteban +6 more
openaire +4 more sources
Engineering Gold Nanoparticle Interaction by PAMAM Dendrimer
, 2016 Bare faceted gold nanoparticles (AuNPs) have a tendency to aggregate through a preferred attachment of the [111] surfaces. We have used fully atomistic classical molecular dynamics simulations to obtain a quantitative estimate of this surface interaction
Prabal K. Maiti (818949) +2 more
core +1 more source
Ötödik generációs PAMAM dendrimer és grafén-oxid kölcsönhatásának vizsgálata
, 2018 Ötödik generációs PAMAM dendrimer és grafén-oxid kölcsönhatására voltunk kiváncsiak. Először külön-külön felvettük a két anyag titrálási görbéját, majd ezeket egyszerre is titráltuk. A kapott görbét összevetettük egy szimulált görbével, amelyet az ismert
Pecsenye, Bence Béla
core
Többgenerációs dendrimerek szerkezeti és fémkomplexeinek relaxációs vizsgálata
, 2020 A dendrimerek szabályos, faágszerűen elágazó szerkezettel rendelkező mesterséges makromolekulák. Munkám során egy ötödik generációs, etilén-diamin (EDA) magvú poli(amido-amin) (PAMAM) dendrimer karboximetilezett származékának vizsgálatával foglalkoztam ...
Hülvely, Bence Marcell
core
, 2016 The interaction between a hydrophobic-functionalized PAMAM dendrimer (PAMAM-NH2-C12, 25%, G4) and bovine serum albumin (BSA) has been investigated by circular dichroism (CD), UV–vis, and fluorescence spectroscopic methods and molecular modeling.
Yan-Qing Wang (1803496) +3 more
core +1 more source
Photoinduced Electron Transfer of PAMAM Dendrimer-Zinc(II) Porphyrin Associates at Polarized Liquid|Liquid Interfaces [PDF]
, 2015 The heterogeneous photoinduced electron-transfer reaction of the ion associates between NH2-terminated polyamidoamine (PAMAM) dendrimers and 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato zinc(II) (ZnTPPS4-) was studied at the polarized water|1,2 ...
Saka, Hiroki +12 more
core +1 more source
Pamam dendrimer-based therapeutic and diagnostic nanodevices [PDF]
, 2011 Dendrimers are ideal materials to be used in the emerging field of nanomedicine. Their nanoscale size and high density of functional groups on their peripheries allow them to be used for various biomedical applications.
Bosnjakovic, Admira
core +1 more source