Results 101 to 110 of about 19,976 (221)

Designing of fucosylated dendrimers as a biocompatible carrier for the targeted delivery of chrysin to human lung cancer cells

Next Materials
Dendrimers, a polymeric macromolecule, have been explored for improving the solubility of water-insoluble drugs, and PAMAM is the most explored dendrimer in nanomedicine. But amine-terminated PAMAM dendrimers confer toxicity to healthy cells.
Divya Bharti Rai, Raghu Solanki, Sunita Patel, Deep Pooja, Hitesh Kulhari   +4 more
doaj   +1 more source

Use of Polyamidoamine Dendrimers in Brain Diseases

Molecules, 2018
Polyamidoamine (PAMAM) dendrimers are one of the smallest and most precise nanomolecules available today, which have promising applications for the treatment of brain diseases. Each aspect of the dendrimer (core, size or generation, size of cavities, and
Maria Florendo, Alexander Figacz, Bhairavi Srinageshwar, Ajit Sharma, Douglas Swanson, Gary L. Dunbar, Julien Rossignol   +6 more
doaj   +1 more source

The complex of PAMAM-OH dendrimer with Angiotensin (1–7) prevented the disuse-induced skeletal muscle atrophy in mice

, 2017
Valeria Márquez-Miranda,1,2,* Johanna Abrigo,3,4,* Juan Carlos Rivera,3,4 Ingrid Araya-Durán,1 Javier Aravena,3,4 Felipe Simon,3,4 Nicolás Pacheco,1 Fernando Danilo González-Nilo,1,2,5 Claudio Cabello-Verrugio3,4 1Center for ...
González-Nilo FD, Abrigo J, Rivera JC, Cabello-Verrugio C, Simon F, Pacheco N, Araya-Durán I, Aravena J, Márquez-Miranda V   +8 more
core  

A novel RGDyC/PEG co-modified PAMAM dendrimer-loaded arsenic trioxide of glioma targeting delivery system

, 2018
Yanping Lu,1 Shunping Han,1 Hongyue Zheng,1 Rui Ma,1 Yuting Ping,1 Jiafeng Zou,1 Hongxia Tang,1 Yongping Zhang,2 Xiuling Xu,1 Fanzhu Li1 1College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China; 2College of ...
Ma R, Zou J, Zheng H, Tang HX, Ping Y, Lu Y, Zhang Y, Li F, Han S, Xu X   +9 more
core  

Engineering Gold Nanoparticle Interaction by PAMAM Dendrimer

, 2013
Bare faceted gold nanoparticles (AuNPs) have a tendency to aggregate through a preferred attachment of the 111] surfaces. We have used fully atomistic classical molecular dynamics simulations to obtain a quantitative estimate of this surface interaction ...
Chandan Dasgupta, Prabal K. Maiti, Mandal, Taraknath, Taraknath Mandal, Maiti, Prabal K, Maiti, Prabal K., Dasgupta, Chandan   +6 more
core   +1 more source

Effect of polyhydroxy-terminated PAMAM dendrimer on dentin matrix metalloproteinases within the hybrid layers. [PDF]

BMC Oral Health, 2023
Luo Y, Si R, He Y, Wang M, Yu Y, Huang X, Huang R, Huang Y, Luo Y, Jin W, Gou Y.   +10 more
europepmc   +1 more source

Preparation of Cu nanocomposites from EDA, DETA, and Jeffamine core PAMAM dendrimers with TRIS and carboxyl surface functional groups

Acta Chimica Slovenica, 2016
This study presents the synthesis and UV-VIS characterization of Cu nanocomposites from (EDA) (E), diethylene triamine (DETA) (D), and Jeffamine® T-403 (P) core PAMAM dendrimers with TRIS and carboxyl surface functional groups.
Ali Serol Ertürk, Mustafa Ulvi Gürbüz, Metin Tülü, Abdürrezzak Emin Bozdoğan   +3 more
doaj   +1 more source

Synthesis and Fluorescent Properties of Dendrimer PAMAM(1G)-FCD

, 2009
A dendrimer of PAMAM (1G)-FCD was synthesized. Its structure was characterized via IR, H-1 NMR, MALDI-TOF-MS, etc. The fluorescent properties of PAMAM(1G) -FCD, as well as the influence of Sn2+ on tills dendrimer, were also studied systematically.
He, Xu-Min, 夏海平, 何旭敏, 王炳祥, 韩巧荣, Ding, Ma-Tai, Han, Qiao-Rong, 丁马太, Xia, Hai-Ping, Wang, Bing-Xiang（Nanjing Normal Univ, Coll Chem & Environm Sci）   +9 more
core  

PAMAM Dendrimer–Drug Interactions: Effect of pH on the Binding and Release Pattern

, 2016
Understanding the dendrimer–drug interaction is of great importance to design and optimize the dendrimer-based drug delivery system. Using atomistic molecular dynamics (MD) simulations, we have analyzed the release pattern of four ligands (two soluble ...
Vishal Maingi (1477951), Prabal K. Maiti (818949), Mattaparthi Venkata Satish Kumar (473113)   +2 more
core   +1 more source

Evolution from Covalent to Self-Assembled PAMAM-Based Dendrimers as Nanovectors for siRNA Delivery in Cancer by Coupled in Silico-Experimental Studies. Part II: Self-Assembled siRNA Nanocarriers

Pharmaceutics, 2019
In part I of this review, the authors showed how poly(amidoamine) (PAMAM)-based dendrimers can be considered as promising delivering platforms for siRNA therapeutics.
Erik Laurini, Domenico Marson, Suzana Aulic, Maurizio Fermeglia, Sabrina Pricl   +4 more
doaj   +1 more source