Results 101 to 110 of about 41,761 (267)

Blood–Brain Barrier: Structure, Function, Diseases, and Drug Delivery Systems

MedComm, Volume 7, Issue 4, April 2026.
This graphical abstract illustrates how blood–brain barrier‐targeted nanomedicine integrates diverse nanocarrier platforms with mechanism‐based therapeutic strategies to overcome delivery barriers in ischemic stroke, enabling targeted modulation of oxidative stress, inflammation, excitotoxicity, and neuronal survival.
Yanan He, Mengyao Qu, Lu Yu, Lipeng He, Yixun Lu, Jin Hong, Miao Sun, Huikai Yang, Weidong Mi, Hang Guo, Yulong Ma   +10 more
wiley   +1 more source

PAMAM dendrimer for mitigating humic foulant

RSC Advances, 2012
Poly(amidoamine) (PAMAM) dendrimers have been established as efficient ligands for the removal of humic acid (HA) foulant, based upon electrostatic and hydrophobic interactions, as well as hydrogen bonding. This proof-of-concept study indicates the broad utility of dendritic nanotechnology for water treatment and environmental applications.
Priyanka Bhattacharya, Nathan Conroy, Apparao M. Rao, Brian A. Powell, David A. Ladner, Pu Chun Ke   +5 more
openaire   +1 more source

Interactions of Poly(amidoamine) Dendrimers with Human Serum Albumin: Binding Constants and Mechanisms [PDF]

, 2011
The interactions of nanomaterials with plasma proteins have a significant impact on their in vivo transport and fate in biological fluids. This article discusses the binding of human serum albumin (HSA) to poly(amidoamine) [PAMAM] dendrimers.
Diallo, Mamadou S., Giri, Jyotsnendu, Goddard, William A., III, Kumar, Rajeev, Liu, Yi, Simpson, André J., Woods, Gwen C.   +6 more
core   +1 more source

Multifunctionalized CMCht/PAMAM dendrimer nanoparticles modulate the cellular uptake by astrocytes and oligodendrocytes in primary cultures of glial cells [PDF]

, 2012
The efficiency of the treatments involving CNS disorders is commonly diminished by the toxicity, reduced stability and lack of targeting of the administered neuroactive compounds.
Albertazzi, Baptiste, Begley, Chandrasekar, Chen, Dommergues, Donnelly, Habgood, Hughes, Kabanov, Kocbek, Maysinger, Modi, Nowacek, Oliveira, Oliveira, Pardridge, Pardridge, Pereira, Popovich, Salgado, Sanvicens, Saovapakhiran, Thanh, Waldmann, Wang, Xu, Zhang, Zlokovic   +28 more
core   +1 more source

Organic Nanoparticles in Food Systems as Antimicrobial Agents: Synthesis Strategies, Functional Properties, and Biofilm Inhibition Mechanisms

Nano Select, Volume 7, Issue 4, April 2026.
Organic nanoparticles (ONPs) derived from biopolymers provide sustainable antimicrobial platforms with tunable physicochemical properties. By enabling controlled delivery of bioactive compounds, ONPs disrupt microbial membranes, induce oxidative stress, and inhibit quorum sensing.
Huy Loc Nguyen, Thi Bich Ngoc Nguyen
wiley   +1 more source

Dendrimers bind antioxidant polyphenols and cisplatin drug.

PLoS ONE, 2012
Synthetic polymers of a specific shape and size play major role in drug delivery systems. Dendrimers are unique synthetic macromolecules of nanometer dimensions with a highly branched structure and globular shape with potential applications in gene and ...
Amine Abderrezak, Philippe Bourassa, Jean-Sebastian Mandeville, Reza Sedaghat-Herati, Heidar-Ali Tajmir-Riahi   +4 more
doaj   +1 more source

Advancing the Landscape of RNAi Nanotherapeutics for Ischemic Heart Disease

Advanced Materials, Volume 38, Issue 17, 20 March 2026.
RNA interference (RNAi) nanomedicine revolutionizes treatment regimens for ischemic heart diseases by enabling tailored, sequence‐anchored gene regulation. This review highlights the recent advances in nanotechnology‐driven RNAi therapeutics for myocardial ischemia and discusses the key design principles that govern efficient delivery, providing ...
Han Gao, Da Pan, Hélder A. Santos
wiley   +1 more source

Molecular modelling of dendrimers for nanoscale applications [PDF]

, 2000
Dendrimers are well defined, highly branched macromolecules that radiate from a central core and are synthesized through a stepwise, repetitive reaction sequence that guarantees complete shells for each generation, leading to polymers that are ...
Breen, Nicholas, Goddard, William A., III, Martin, Ryan, Wang, Guofeng, Çağin, Tahir   +4 more
core  

Dendrimer-Encapsulated Nanoparticles: New Synthetic and Characterization Methods and Catalytic Applications [PDF]

, 2011
In this article we describe the synthesis, characterization, and applications of dendrimer-encapsulated nanoparticles (DENs). These materials are synthesized using a template approach in which metal ions are extracted into the interior of dendrimers and ...
Carino, Emily V., Crooks, Richard M., Myers, V. Sue, Pande, Surojit, Weir, Michael G., Yancey, David F.   +5 more
core   +1 more source

Induction of a robust immune response against avian influenza virus following transdermal inoculation with H5-DNA vaccine formulated in modified dendrimer-based delivery system in mouse model

International Journal of Nanomedicine, 2017
Azadeh Bahadoran,1,2 Mehdi Ebrahimi,3 Swee Keong Yeap,1 Nikoo Safi,1 Hassan Moeini,4 Mohd Hair-Bejo,1,5 Mohd Zobir Hussein,6 Abdul Rahman Omar1,5 1Institute of Bioscience, Universiti Putra Malaysia, UPM, Serdang, 2Department of Microbiology, Faculty of ...
Bahadoran A, Ebrahimi M, Yeap SK, Safi N, Moeini H, Hair-Bejo M, Hussein MZ, Omar AR   +7 more
doaj