Results 121 to 130 of about 41,761 (267)

Designing of fucosylated dendrimers as a biocompatible carrier for the targeted delivery of chrysin to human lung cancer cells

Next Materials
Dendrimers, a polymeric macromolecule, have been explored for improving the solubility of water-insoluble drugs, and PAMAM is the most explored dendrimer in nanomedicine. But amine-terminated PAMAM dendrimers confer toxicity to healthy cells.
Divya Bharti Rai, Raghu Solanki, Sunita Patel, Deep Pooja, Hitesh Kulhari   +4 more
doaj   +1 more source

Use of Polyamidoamine Dendrimers in Brain Diseases

Molecules, 2018
Polyamidoamine (PAMAM) dendrimers are one of the smallest and most precise nanomolecules available today, which have promising applications for the treatment of brain diseases. Each aspect of the dendrimer (core, size or generation, size of cavities, and
Maria Florendo, Alexander Figacz, Bhairavi Srinageshwar, Ajit Sharma, Douglas Swanson, Gary L. Dunbar, Julien Rossignol   +6 more
doaj   +1 more source

Lipodendriplexes: A promising nanocarrier for enhanced nucleic acid delivery [PDF]

, 2019
The main objective of the current study was to developed an optimized system for enhanced nucleic acid delivery with minimum cytotoxicity. For efficient therapeutic gene delivery, PAMAM dendrimer, with ethylenediamine core was chosen due to its ...
Tariq, Imran
core   +1 more source

Photosensitizer and peptide-conjugated PAMAM dendrimer for targeted in vivo photodynamic therapy

International Journal of Nanomedicine, 2015
Challenges in photodynamic therapy (PDT) include development of efficient near infrared-sensitive photosensitizers (5,10,15,20-tetrakis(4-hydroxyphenyl)-21H,23H-porphine [PS]) and targeted delivery of PS to the tumor tissue.
Amreddy Narsireddy, K. Vijayashree, Mahesh G Adimoolam, S. Manorama, N. Rao   +4 more
semanticscholar   +1 more source

Effect of polyhydroxy-terminated PAMAM dendrimer on dentin matrix metalloproteinases within the hybrid layers. [PDF]

BMC Oral Health, 2023
Luo Y, Si R, He Y, Wang M, Yu Y, Huang X, Huang R, Huang Y, Luo Y, Jin W, Gou Y.   +10 more
europepmc   +1 more source

Nanomaterials for Healthcare Biosensing Applications [PDF]

, 2019
In recent years, an increasing number of nanomaterials have been explored for their applications in biomedical diagnostics, making their applications in healthcare biosensing a rapidly evolving field.
Altintas, Zeynep, Pirzada, Muqsit
core   +1 more source

Dendrimers and derivatives as a potential therapeutic tool in regenerative medicine strategies : a review [PDF]

, 2010
Since the pioneering work dealing with the synthesis and physicochemical aspects of dendrimers, a predictable and tunable set of compositions for therapeutic, scaffolding and imaging systems has been reported.
Mano, J. F., Oliveira, Joaquim M., Reis, R. L., Salgado, A. J., Sousa, Nuno   +4 more
core   +1 more source

Selective aggregation of PAMAM dendrimer nanocarriers and PAMAM/ZnPc nanodrugs on human atheromatous carotid tissues: a photodynamic therapy for atherosclerosis

Nanoscale Research Letters, 2015
Photodynamic therapy (PDT) involves the action of photons on photosensitive molecules, where atomic oxygen or OH− molecular species are locally released on pathogenic human cells, which are mainly carcinogenic, thus causing cell necrosis. The efficacy of
Nikolaos Spyropoulos-Antonakakis, E. Sarantopoulou, Panagiotis N. Trohopoulos, Aikaterina L. Stefi, Z. Kollia, V. Gavriil, A. Bourkoula, P. Petrou, S. Kakabakos, V. Semashko, A. Nizamutdinov, A. Cefalas   +11 more
semanticscholar   +1 more source

An Evaluation of CXCR4 Targeting with PAMAM Dendrimer Conjugates for Oncologic Applications. [PDF]

Pharmaceutics, 2022
Lesniak WG, Azad BB, Chatterjee S, Lisok A, Pomper MG.   +4 more
europepmc   +1 more source

Preparation of Cu nanocomposites from EDA, DETA, and Jeffamine core PAMAM dendrimers with TRIS and carboxyl surface functional groups

Acta Chimica Slovenica, 2016
This study presents the synthesis and UV-VIS characterization of Cu nanocomposites from (EDA) (E), diethylene triamine (DETA) (D), and Jeffamine® T-403 (P) core PAMAM dendrimers with TRIS and carboxyl surface functional groups.
Ali Serol Ertürk, Mustafa Ulvi Gürbüz, Metin Tülü, Abdürrezzak Emin Bozdoğan   +3 more
doaj   +1 more source