Results 81 to 90 of about 7,965 (226)

Engineering Gold Nanoparticle Interaction by PAMAM Dendrimer

, 2016
Bare faceted gold nanoparticles (AuNPs) have a tendency to aggregate through a preferred attachment of the [111] surfaces. We have used fully atomistic classical molecular dynamics simulations to obtain a quantitative estimate of this surface interaction
Prabal K. Maiti (818949), Taraknath Mandal (1738267), Chandan Dasgupta (1455118)   +2 more
core   +1 more source

Induction of a robust immune response against avian influenza virus following transdermal inoculation with H5-DNA vaccine formulated in modified dendrimer-based delivery system in mouse model

International Journal of Nanomedicine, 2017
Azadeh Bahadoran,1,2 Mehdi Ebrahimi,3 Swee Keong Yeap,1 Nikoo Safi,1 Hassan Moeini,4 Mohd Hair-Bejo,1,5 Mohd Zobir Hussein,6 Abdul Rahman Omar1,5 1Institute of Bioscience, Universiti Putra Malaysia, UPM, Serdang, 2Department of Microbiology, Faculty of ...
Bahadoran A, Ebrahimi M, Yeap SK, Safi N, Moeini H, Hair-Bejo M, Hussein MZ, Omar AR   +7 more
doaj  

Molecular dynamics study of pH-responsive PAMAM dendrimer–topotecan complex: loading mechanism, membrane transport, and release mechanism

Results in Surfaces and Interfaces
The clinical efficacy of topotecan (TPT) is limited by its instability and rapid clearance, motivating the search for nanoscale carriers capable of enhancing its delivery.
Mehdi Yoosefian, Elham Rahmanifar, Vahid Saheb, Kasim Sakran Abass   +3 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, Volume 16, Issue 5, Page 944-965, May 2026.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

PAMAM dendrimer derivatives as a potential drug for antithrombotic therapy

European Journal of Medicinal Chemistry, 2013
Platelets are anucleated blood cells that play an important role both in the pathogenesis of atherosclerosis and subsequent thrombosis. Dendrimers have attracted great interest in biomedical applications. However, their interactions with cell compounds and compartments are nonselective, thus causing cytotoxicity and hemotoxicity.
Duran-Lara, Esteban, Guzman, Luis, John, Amalraj, Fuentes, Eduardo, Alarcon, Marcelo, Palomo, Ivan, Santos, Leonardo S.   +6 more
openaire   +4 more sources

Ötödik generációs PAMAM dendrimer és grafén-oxid kölcsönhatásának vizsgálata

, 2018
Ötödik generációs PAMAM dendrimer és grafén-oxid kölcsönhatására voltunk kiváncsiak. Először külön-külön felvettük a két anyag titrálási görbéját, majd ezeket egyszerre is titráltuk. A kapott görbét összevetettük egy szimulált görbével, amelyet az ismert
Pecsenye, Bence Béla
core  

Többgenerációs dendrimerek szerkezeti és fémkomplexeinek relaxációs vizsgálata

, 2020
A dendrimerek szabályos, faágszerűen elágazó szerkezettel rendelkező mesterséges makromolekulák. Munkám során egy ötödik generációs, etilén-diamin (EDA) magvú poli(amido-amin) (PAMAM) dendrimer karboximetilezett származékának vizsgálatával foglalkoztam ...
Hülvely, Bence Marcell
core  

In vitro antibacterial activity of poly (amidoamine)-G7 dendrimer

BMC Infectious Diseases, 2017
Background Nano-scale dendrimers are synthetic macromolecules that frequently used in medical and health field. Traditional anibiotics are induce bacterial resistence so there is an urgent need for novel antibacterial drug invention. In the present study
Mitra Gholami, Rashin Mohammadi, Mohsen Arzanlou, Fakhraddin Akbari Dourbash, Ebrahim Kouhsari, Gharib Majidi, Seyed Mohsen Mohseni, Shahram Nazari   +7 more
doaj   +1 more source

Interaction of a Hydrophobic-Functionalized PAMAM Dendrimer with Bovine Serum Albumin: Thermodynamic and Structural Changes

, 2016
The interaction between a hydrophobic-functionalized PAMAM dendrimer (PAMAM-NH2-C12, 25%, G4) and bovine serum albumin (BSA) has been investigated by circular dichroism (CD), UV–vis, and fluorescence spectroscopic methods and molecular modeling.
Yan-Qing Wang (1803496), Hong-Mei Zhang (105829), Kai Lou (1803493), Jian Cao (16485)   +3 more
core   +1 more source

The complex of PAMAM-OH dendrimer with Angiotensin (1–7) prevented the disuse-induced skeletal muscle atrophy in mice

, 2017
Valeria Márquez-Miranda,1,2,* Johanna Abrigo,3,4,* Juan Carlos Rivera,3,4 Ingrid Araya-Durán,1 Javier Aravena,3,4 Felipe Simon,3,4 Nicolás Pacheco,1 Fernando Danilo González-Nilo,1,2,5 Claudio Cabello-Verrugio3,4 1Center for ...
González-Nilo FD, Abrigo J, Rivera JC, Cabello-Verrugio C, Simon F, Pacheco N, Araya-Durán I, Aravena J, Márquez-Miranda V   +8 more
core