Results 11 to 20 of about 7,965 (226)
PAMAM dendrimer - cell membrane interactions [PDF]
Advances in Colloid and Interface Science, 2018 PAMAM dendrimers have been conjectured for a wide range of biomedical applications due to their tuneable physicochemical properties. However, their application has been hindered by uncertainties in their cytotoxicity, which is influenced by dendrimer generation (i.e.
Fox, Laura J +2 more
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Inverse Polyamidoamine (i‐PAMAM) Dendrimer Antimicrobials [PDF]
Helvetica Chimica Acta, 2023 AbstractHere we redesigned the branches of polyamidoamine (PAMAM) dendrimers by moving the amide carbonyl group on the other side of the amide nitrogen atom, transforming the β‐alaninyl‐amidoethylamine branch, which easily undergoes retro‐Michael reactions and renders PAMAMs intrinsically unstable, into a more stable glycyl‐amidopropylamine branch. The
Bonvin, Etienne, Reymond, Jean-Louis
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International Journal of Nanomedicine, 2011 Naimin Shao1, Yunzhang Su1, Jingjing Hu2, Jiahai Zhang3, Hongfeng Zhang1, Yiyun Cheng1,41School of Life Sciences, East China Normal University, Shanghai, 2CAS Key Laboratory of Soft Matter Chemistry, Department of Chemistry, University of Science and ...
Shao N +5 more
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PAMAM dendrimer: a pH-controlled nanosponge [PDF]
Canadian Journal of Chemistry, 2017 Using fully atomistic molecular dynamics simulation that are several hundred nanoseconds long, we demonstrate the pH-controlled sponge action of PAMAM dendrimer. We show how at varying pH levels, the PAMAM dendrimer acts as a wet sponge; at neutral or low pH levels, the dendrimer expands noticeably and the interior of the dendrimer opens up to host ...
Maiti, Prabal K, Prabal K. Maiti
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, 2021 Chlorhexidine digluconate (CHG) is a cationic bisbiguanide used in the UK as the first-line skin antiseptic prior to surgery in the UK due to its favourable efficacy and safety profile, high affinity for skin binding and minimal reports of resistance ...
Scurr, David J. +3 more
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Spectroelectrochemical analysis of ion-transfer and adsorption of the PAMAM dendrimer at a polarized liquid|liquid interface [PDF]
, 2008 Interfacial behavior of the fourth generation polyamidoamine (G4 PAMAM) dendrimer at the water|1,2-dichloroethane (DCE) interface was studied by the cyclic voltammetry and the potential modulated fluorescence (PMF) spectroscopy.
Sagara, Takamasa +2 more
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Development of Tat-Conjugated Dendrimer for Transdermal DNA Vaccine Delivery
Journal of Pharmacy & Pharmaceutical Sciences, 2016 PURPOSE: In order to enhance cellular uptake and to facilitate transdermal delivery of DNA vaccine, polyamidoamine (PAMAM) dendrimers conjugated with HIV transactivator of transcription (TAT) was developed.
Azadeh Bahadoran +4 more
doaj +1 more source
Comparative Evaluation of Lipofectamine and Dendrimer for Transfection of Short RNA Into Human T47D and MCF-10A Cell Lines [PDF]
Advanced Pharmaceutical Bulletin, 2023 Purpose: Non-viral transfection approaches are extensively used in cancer therapy. The future of cancer therapy lies on targeted and efficient drug/gene delivery.
Zohreh Jahanafrooz +2 more
doaj +1 more source
A novel RGDyC/PEG co-modified PAMAM dendrimer-loaded arsenic trioxide of glioma targeting delivery system. [PDF]
Int J Nanomedicine, 2018 Yanping Lu,1 Shunping Han,1 Hongyue Zheng,1 Rui Ma,1 Yuting Ping,1 Jiafeng Zou,1 Hongxia Tang,1 Yongping Zhang,2 Xiuling Xu,1 Fanzhu Li1 1College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China; 2College of ...
Lu Y +9 more
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Acetylation of PAMAM dendrimers for cellular delivery of siRNA [PDF]
BMC Biotechnology, 2009 AbstractBackgroundThe advancement of gene silencing via RNA interference is limited by the lack of effective short interfering RNA (siRNA) delivery vectors. Rational design of polymeric carriers has been complicated by the fact that most chemical modifications affect multiple aspects of the delivery process.
Waite, Carolyn L +3 more
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