Results 21 to 30 of about 23,240 (264)

Superelastic and pH-Responsive Degradable Dendrimer Cryogels Prepared by Cryo-aza-Michael Addition Reaction

Scientific Reports, 2018
Dendrimers exhibit super atomistic features by virtue of their well-defined discrete quantized nanoscale structures. Here, we show that hyperbranched amine-terminated polyamidoamine (PAMAM) dendrimer G4.0 reacts with linear polyethylene glycol (PEG ...
Juan Wang, Hu Yang
doaj   +1 more source

Polyamidoamine dendrimer-conjugated triamcinolone acetonide attenuates nerve injury-induced spinal cord microglia activation and mechanical allodynia

Molecular Pain, 2017
Background Accumulating evidence on the causal role of spinal cord microglia activation in the development of neuropathic pain after peripheral nerve injury suggests that microglial activation inhibitors might be useful analgesics for neuropathic pain ...
Hwisung Kim, Boomin Choi, Hyoungsub Lim, Hyunjung Min, Jae Hoon Oh, Sunghyun Choi, Joung Goo Cho, Jong-Sang Park, Sung Joong Lee   +8 more
doaj   +1 more source

Dendrimers in Layer-by-Layer Assemblies: Synthesis and Applications

Molecules, 2013
We review the synthesis of dendrimer-containing layer-by-layer (LbL) assemblies and their applications, including biosensing, controlled drug release, and bio-imaging.
Katsuhiko Sato, Jun-ichi Anzai
doaj   +1 more source

Erlotinib-Loaded Dendrimer Nanocomposites as a Targeted Lung Cancer Chemotherapy

Molecules, 2023
Lung cancer is the main cause of cancer-related mortality globally. Erlotinib is a tyrosine kinase inhibitor, affecting both cancerous cell proliferation and survival.
Wafa K. Fatani, Fadilah S. Aleanizy, Fulwah Y. Alqahtani, Mohammed M. Alanazi, Abdullah A. Aldossari, Faiyaz Shakeel, Nazrul Haq, Hosam Abdelhady, Hamad M. Alkahtani, Ibrahim A. Alsarra   +9 more
doaj   +1 more source

Dendrimer-based posaconazole nanoplatform for antifungal therapy

, 2021
We examined formulating a new antifungal agent, posaconazole (POS) and its derivatives, with different molecular vehicles. Several combinations of drug and carrier molecules were synthesized, and their antifungal activities were evaluated against ...
Jesse Chen (10312758), Jayme Cannon (3756121), Shengzhuang Tang (1469533), James R. Baker Jr (10312767), Zhengyi Cao (52490), Su He Wang (1852102)   +5 more
core   +1 more source

Dendrimer-Functionalized Nanodiamonds as Safe and Efficient Drug Carriers for Cancer Therapy: Nucleus Penetrating Nanoparticles

Nanodiamonds (NDs) are increasingly being assessed as potential candidates for drug delivery in cancer cells and they hold great promise in overcoming the side effects of traditional chemotherapeutics.
Vishnu S. Mishra (12961732), Sachin Patil (3301101), Puli Chandramouli Reddy (6533948), Nisha Yadav (366131), Bimlesh Lochab (1462495)   +4 more
core   +4 more sources

Dendrimers, Dendrons, and the Dendritic State: Reflection on the Last Decade with Expected New Roles in Pharma, Medicine, and the Life Sciences

Pharmaceutics
This perspective begins with an overview of the major impact that the dendron, dendrimer, and dendritic state (DDDS) discovery has made on traditional polymer science.
Donald A. Tomalia
doaj   +1 more source

Synthesis, Internalization and Visualization of N-(4-Carbomethoxy) Pyrrolidone Terminated PAMAM [G5:G3-TREN] Tecto(dendrimers) in Mammalian Cells

Molecules, 2020
Tecto(dendrimers) are well-defined, dendrimer cluster type covalent structures. In this article, we present the synthesis of such a PAMAM [G5:G3-(TREN)]-N-(4-carbomethoxy) pyrrolidone terminated tecto(dendrimer).
Maciej Studzian, Paula Działak, Łukasz Pułaski, David M. Hedstrand, Donald A. Tomalia, Barbara Klajnert-Maculewicz   +5 more
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Dendrimers in gene delivery

, 2005
Dendrimers have unique molecular architectures and properties that make them attractive materials for the development of nanomedicines. Key properties such as defined architecture and a high ratio of multivalent surface moieties to molecular volume also ...
Dufès, Christine, Uchegbu, Ijeoma F., Schätzlein, Andreas G.   +2 more
core   +1 more source

Investigations on The Mechanism of Artificial Photosynthesis of Ca-Pc-PDI and Dendrimer Molecule by DFT Calculations

Jurnal Ilmu Dasar, 2018
Artificial photosynthesis modelling of Ca-Pc-PDI complex Ca Phthalocyanine Perylenediimide), and dendrimer molecule using Density of Functional Theory (DFT) Method has been studied to showed the energy efficiency of these compounds in terms of electron ...
Rahmat Gunawan, Ulinnuha Hammamiyah, Fahmi Fadillah, Chairul Saleh, Saibun Sitorus   +4 more
doaj   +1 more source