Results 21 to 30 of about 42,261 (248)

Original Multivalent Gold (III) and Dual Gold(III)-Copper(II) Conjugated Phosphorus Dendrimers as Potent Antitumoral and Antimicrobial Agents [PDF]

open access: yes, 2017
Original metallophosphorus dendrimers (generation 3, 48 terminal groups) have been prepared via the complexation of phosphorus dendrimers bearing imino-pyridino end groups with Au(III) or with both Au(III) and Cu(II).
Serge M. Mignani   +11 more
core   +2 more sources

Dendrimers in gene delivery [PDF]

open access: yes, 2005
Dendrimers have unique molecular architectures and properties that make them attractive materials for the development of nanomedicines. Key properties such as defined architecture and a high ratio of multivalent surface moieties to molecular volume also ...
Dufès, Christine   +2 more
core   +1 more source

Pharmacokinetics of Chiral Dendrimer-Triamine-Coordinated Gd-MRI Contrast Agents Evaluated by in Vivo MRI and Estimated by in Vitro QCM

open access: yesSensors, 2015
Recently, we developed novel chiral dendrimer-triamine-coordinated Gd-MRI contrast agents (Gd-MRI CAs), which showed longitudinal relaxivity (r1) values about four times higher than that of clinically used Gd-DTPA (Magnevist®, Bayer).
Yuka Miyake   +8 more
doaj   +1 more source

Structure of polyamidoamide dendrimers up to limiting generations : a mesoscale description [PDF]

open access: yes, 2009
The polyamidoamide (PAMAM) class of dendrimers was one of the first dendrimers synthesized by Tomalia and co-workers at Dow. Since its discovery the PAMAMs have stimulated many discussions on the structure and dynamics of such hyperbranched polymers ...
Goddard, William A., III   +3 more
core   +1 more source

Structure of Carbon Nanotube-dendrimer composite

open access: yes, 2012
Using all atomistic molecular dynamics (MD) simulations we report the microscopic picture of the nanotube-dendrimer complex for PAMAM dendrimer of generation 2 to 4 and carbon nanotube of chirality (6,5).
Maiti, Prabal K   +3 more
core   +1 more source

Dendritic glycopolymers based on dendritic polyamine scaffolds: view on their synthetic approaches, characteristics and potential for biomedical applications [PDF]

open access: yes, 2014
In this review we highlight the potential for biomedical applications of dendritic glycopolymers based on polyamine scaffolds. The complex interplay of the molecular characteristics of the dendritic architectures and their specific interactions with ...
Abbott   +278 more
core   +2 more sources

Polyamidoamine dendrimer-conjugated triamcinolone acetonide attenuates nerve injury-induced spinal cord microglia activation and mechanical allodynia

open access: yesMolecular Pain, 2017
Background Accumulating evidence on the causal role of spinal cord microglia activation in the development of neuropathic pain after peripheral nerve injury suggests that microglial activation inhibitors might be useful analgesics for neuropathic pain ...
Hwisung Kim   +8 more
doaj   +1 more source

Dendrimers in Layer-by-Layer Assemblies: Synthesis and Applications

open access: yesMolecules, 2013
We review the synthesis of dendrimer-containing layer-by-layer (LbL) assemblies and their applications, including biosensing, controlled drug release, and bio-imaging.
Katsuhiko Sato, Jun-ichi Anzai
doaj   +1 more source

Erlotinib-Loaded Dendrimer Nanocomposites as a Targeted Lung Cancer Chemotherapy

open access: yesMolecules, 2023
Lung cancer is the main cause of cancer-related mortality globally. Erlotinib is a tyrosine kinase inhibitor, affecting both cancerous cell proliferation and survival.
Wafa K. Fatani   +9 more
doaj   +1 more source

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