Results 51 to 60 of about 54,440 (362)
Dendrimers for siRNA Delivery [PDF]
Pharmaceuticals, 2013 Since the discovery of the “starburst polymer”, later renamed as dendrimer, this class of polymers has gained considerable attention for numerous biomedical applications, due mainly to the unique characteristics of this macromolecule, including its monodispersity, uniformity, and the presence of numerous functionalizable terminal groups.
Swati Biswas, Vladimir P. Torchilin
openaire +4 more sources
Dendrimers as Antiamyloid Agents
Pharmaceutics, 2022 Dendrimer–protein conjugates have significant prospects for biological applications. The complexation changes the biophysical behavior of both proteins and dendrimers. The dendrimers could influence the secondary structure of proteins, zeta-potential, distribution of charged regions on the surface, the protein–protein interactions, etc.
Svetlana A. Sorokina +1 more
openaire +3 more sources
Structure of poly(propyl ether imine) (PETIM) dendrimer from fully atomistic molecular Dynamics Simulation and by Small Angle X-ray scattering [PDF]
JCP, 124, 204719 (2006), 2006 We study the structure of carboxylic acid terminated neutral poly (propyl ether imine) (PETIM) dendrimer from generation 1 through 6 (G1-G6) in a good solvent (water) by fully atomistic molecular dynamics (MD) simulations. We determine as a function of generation such structural properties as: radius of gyration, shape tensor, asphericity, fractal ...
arxiv +1 more source
Molecules, 2020 Tecto(dendrimers) are well-defined, dendrimer cluster type covalent structures. In this article, we present the synthesis of such a PAMAM [G5:G3-(TREN)]-N-(4-carbomethoxy) pyrrolidone terminated tecto(dendrimer).
Maciej Studzian +5 more
doaj +1 more source
ACS Applied Materials and Interfaces, 2017 In this work, we describe synthesis and characterization of novel in situ-forming polyamidoamine (PAMAM) dendrimer hydrogels (DHs) with tunable properties prepared via highly efficient aza-Michael addition reaction.
Juan Wang +3 more
semanticscholar +1 more source
Trapping time statistics and efficiency of transport of optical excitations in dendrimers [PDF]
J. Chem. Phys. 121, 4884 (2004), 2004 We theoretically study the trapping time distribution and the efficiency of the excitation energy transport in dendritic systems. Trapping of excitations, created at the periphery of the dendrimer, on a trap located at its core, is used as a probe of the efficiency of the energy transport across the dendrimer.
arxiv +1 more source
Brain and Behavior, Volume 12, Issue 12, December 2022., 2022 Abstract Objective This study sought to evaluate the feasibility of multifunctional gastrodin (GAS)‐containing nano‐drug carrier system against cerebral ischemia–reperfusion injury (CIRI). Methods The drug‐loaded nanocomposite (Au‐G5.NHAc‐PS/GAS) with certain encapsulation efficiency (EE) was prepared by physical adsorption method using different ...
Wenqiang Huang +8 more
wiley +1 more source
Biomolecules, 2019 Dendrimers are nanosized, arborescent polymers of which size and structure are perfectly controlled. This is one reason why they are widely used for biomedical purposes.
Séverine Fruchon +9 more
doaj +1 more source
Nature Communications, 2016 Understanding the relationship between the location of nanoparticles (NPs) in an organic matrix and their catalytic performances is essential for catalyst design.
Xiang Liu +8 more
semanticscholar +1 more source
Some New Aspects of Dendrimer Applications [PDF]
J. Lumin. 111, 315-325 (2005), 2004 Dendrimers are characterized by special features that make them promising candidates for many applications. Here we focus on two such applications: dendrimers as light harvesting antennae, and dendrimers as molecular amplifiers, which may serve as novel platforms for drug delivery. Both applications stem from the unique structure of dendrimers.
arxiv +1 more source