Results 21 to 30 of about 54,619 (251)

Click Chemistry of Melamine Dendrimers: Comparison of “Click-and-Grow” and “Grow-Then-Click” Strategies Using a Divergent Route to Diversity

Molecules, 2022
Dendrimers are attractive macromolecules for a broad range of applications owing to their well-defined shapes and dimensions, highly branched and globular architectures, and opportunities for exploiting multivalency.
Sanami Numai, Risako Yoto, Masataka Kimura, Eric E. Simanek, Yoshikazu Kitano   +4 more
doaj   +1 more source

Molecular Dynamics Study of Charged Dendrimers in Salt-Free Solution: Effect of Counterions [PDF]

, 2005
Polyamidoamine (PAMAM) dendrimers, being protonated under physiological conditions, represent a promising class of nonviral, nano-sized vectors for drug and gene delivery. We performed extensive molecular dynamics simulations of a generic model dendrimer
Andrey A. Gurtovenko, Galperin D. E., Ilpo Vattulainen, Mikko Karttunen, Sergey V. Lyulin   +4 more
core   +3 more sources

Cytotoxicity of Dendrimers [PDF]

Biomolecules, 2019
Drug delivery systems are molecular platforms in which an active compound is packed into or loaded on a biocompatible nanoparticle. Such a solution improves the activity of the applied drug or decreases its side effects. Dendrimers are promising molecular platforms for drug delivery due to their unique properties.
Anna Janaszewska, Joanna Lazniewska, Przemysław Trzepiński, Monika Marcinkowska, Barbara Klajnert-Maculewicz   +4 more
openaire   +4 more sources

Dendritic glycopolymers based on dendritic polyamine scaffolds: view on their synthetic approaches, characteristics and potential for biomedical applications [PDF]

, 2014
In this review we highlight the potential for biomedical applications of dendritic glycopolymers based on polyamine scaffolds. The complex interplay of the molecular characteristics of the dendritic architectures and their specific interactions with ...
Abbott, Agarwal, Agashe, Agashe, Agrawal, Agrawal, Albersheim, Albertazzi, Amir, Anajwala, Andre, Andre, Andre, Anna Janaszewska, Antoni, Antoni, Aoi, Appelhans, Appelhans, Arima, Arima, Arima, Arima, Arima, Baek, Baigude, Baigude, Baker, Bandaru, Barbara Klajnert-Maculewicz, Barner-Kowollik, Bettinger, Bhadra, Bhadra, Boas, Bogdan, Bogdan, Bojarova, Borges, Boye, Branco de Barros, Branderhorst, Branson, Brigitte Voit, Calderon, Carlmark, Carlmark, Chabre, Chabre, Chabre, Chen, Chen, Cheng, Cheng, Choudhury, Ciepluch, Ciolkowski, Ciolkowski, Cloninger, Conte, Cook, Cummins, Danishefsky, de Paz, Diebold, Dietmar Appelhans, Dolenc, Dominguez, Dondoni, Drzewinska, Duncan, Duncan, Dutta, Dutta, Dutta, Dutta, Ennen, Erbacher, Fajac, Filimon, Fischer, Franiak-Pietryga, Gabius, Gajbhiye, Gajbhiye, Gajbhiye, Gajbhiye, Gajbhiye, Garcia-Vallejo, Garg, Ghirardello, Gorelik, Gorityala, Gringas, Grobarova, Grosse, Grosse, Grosse, Gupta, Gupta, Gutsch, Hatano, Hauptmann, Hauptmann, He, Hu, Höbel, Iha, Ikeda, Imberty, Ina, Jain, Jain, Jain, Jain, Jain, Jain, Janaszewska, Janaszewska, Jararaman, Jararaman, Jayaraman, Jia, Joanna Lazniewska, Kade, Kaminskas, Kantchev, Kempe, Kensinger, Kensinger, Kesharwani, Kiessling, Kihara, Kihara, Kim, Klajnert, Klajnert, Klajnert, Klajnert, Klajnert, Klementieva, Klementieva, Kottari, Krist, Ku, Kuhlbeil, Kumar, Kunath, Kuo, Kuo, Kurmi, Köth, Laurino, Leclercq, Lee, Li, Lindhorst, Liu, Liu, Llinares, Lopez-Marin, Ma, Majoinen, Malik, Maly, Mangold, Marradi, Martos, Martínez, Matsushita, Matsushita, McCarthy, McCarthy, McCarthy, McCarthy, McNermy, Medina, Medina, Medina, Mignani, Mignani, Mignani, Mignani, Milowska, Misra, Mkandawire, Monsigny, Motoyama, Nahar, Narayan, Needham, Nepogodiev, Nicolas, Niederhafener, Niederhafener, Niederhafener, Ogiso, Oka, Oka, Ottaviani, Palcic, Paolino, Paolino, Papadopoulos, Park, Park, Park, Park, Patel, Pedziwiatr-Werbicka, Percec, Polikarpov, Richter, Robb, Ross, Roy, Roy, Roy, Roy, Rudd, Röckendorf, Sakamoto, Santoyo-Gonzáles, Santoyo-Gonzáles, Sapsford, Sashiwa, Satoh, Schengrund, Seah, Sethi, Shah, Sharma, Sharon, Shaunak, Shcharbin, Shiao, Sinha, Solassol, Stefani, Sun, Supattapone, Svenson, Svenson, Szewczyk, Szulc, Szulc, Tekade, ten Brummelhuis, Thünemann, Ting, Touaibia, Tripp, Tsutsumiuchi, Turnbull, Vacas Córdoba, Vepŕek, Wada, Wada, Walter, Wang, Wang, Wang, Warenda, Wasiak, Wijagkanalan, Wolfenden, Woller, Wood, Wu, Wu, Zanini, Zanini, Zanta, Zhang, Ziemba, Ziemba, Ziemba, Ziemba, Zinselmeyer   +278 more
core   +2 more sources

Which Dendrimer to Attain the Desired Properties? Focus on Phosphorhydrazone Dendrimers

Molecules, 2018
Among the six Critical Nanoscale Design Parameters (CNDPs) proposed by Prof. Donald A. Tomalia, this review illustrates the influence of the sixth one, which concerns the elemental composition, on the properties of dendrimers.
Anne-Marie Caminade, Jean-Pierre Majoral
doaj   +1 more source

Polyamidoamine (PAMAM) dendrimers synthesis, characterization and adsorptive removal of nickel ions from aqueous solution

Journal of Materials Research and Technology, 2020
Nickel is a toxic metal and present in the effluents of electroplating industries. Conventional methods to remove nickel are expensive and ineffective. Heavy metals can be easily adsorbed by dendrimers.
Isra Sohail, Ijaz Ahmad Bhatti, Ambreen Ashar, Fazli Malik Sarim, Muhammad Mohsin, Rizwana Naveed, Muhammad Yasir, Munawar Iqbal, Arif Nazir   +8 more
doaj   +1 more source

Application of Dendrimers in Anticancer Diagnostics and Therapy

Molecules, 2022
The application of dendrimeric constructs in medical diagnostics and therapeutics is increasing. Dendrimers have attracted attention due to their compact, spherical three-dimensional structures with surfaces that can be modified by the attachment of ...
Zuzanna Bober, Dorota Bartusik-Aebisher, David Aebisher   +2 more
doaj   +1 more source

T Cell-Association of Carboxy-Terminal Dendrimers with Different Bound Numbers of Phenylalanine and Their Application to Drug Delivery

Pharmaceutics, 2023
T cells play important roles in various immune reactions, and their activation is necessary for cancer immunotherapy. Previously, we showed that polyamidoamine (PAMAM) dendrimers modified with 1,2-cyclohexanedicarboxylic acid (CHex) and phenylalanine ...
Hiroya Shiba, Tomoka Hirose, Yunshen Fu, Masataka Michigami, Ikuo Fujii, Ikuhiko Nakase, Akikazu Matsumoto, Chie Kojima   +7 more
doaj   +1 more source

Analysis of Biotinylated Generation 4 Poly(amidoamine) (PAMAM) Dendrimer Distribution in the Rat Brain and Toxicity in a Cellular Model of the Blood-Brain Barrier

Molecules, 2013
Dendrimers are highly customizable nanopolymers with qualities that make them ideal for drug delivery. The high binding affinity of biotin/avidin provides a useful approach to fluorescently label synthesized dendrimer-conjugates in cells and tissues.
Heather A. Bullen, Kristi L. Haik, Celeste Morris, Steven Wall, Anthony Haskamp, Megan Caroway, Michael Hester, Robert Spaulding, Brett Rossow, Ruth Hemmer, Andrew Hall   +10 more
doaj   +1 more source

Nanoparticle Effects on Human Platelets in Vitro: A Comparison between PAMAM and Triazine Dendrimers

Molecules, 2016
Triazine and PAMAM dendrimers of similar size and number of cationic surface groups were compared for their ability to promote platelet aggregation. Triazine dendrimers (G3, G5 and G7) varied in molecular weight from 8 kDa–130 kDa and in surface groups ...
Alan E. Enciso, Barry Neun, Jamie Rodriguez, Amalendu P. Ranjan, Marina A. Dobrovolskaia, Eric E. Simanek   +5 more
doaj   +1 more source