Results 21 to 30 of about 31,221 (269)

PAMAM-Calix-Dendrimers: Second Generation Synthesis, Fluorescent Properties and Catecholamines Binding

Pharmaceutics, 2022
A convenient method for the synthesis of the second generation of PAMAM dendrimers based on a p-tert-butylthiacalix[4]arene core in cone, partial cone and 1,3-alternate conformations was developed.
Olga Mostovaya, Igor Shiabiev, Dmitry Pysin, Alesia Stanavaya, Viktar Abashkin, Dzmitry Shcharbin, Pavel Padnya, Ivan Stoikov   +7 more
doaj   +1 more source

Synthesis and characterization of PEG-functionalized graphene oxide as an effective pH-sensitive drug carrier

Artificial Cells, Nanomedicine, and Biotechnology, 2019
In the present work, PEG4000 as a hydrophilic polymer was conjugated to the surface of graphene oxide (GO) for effective drug loading and targeting release of doxorubicin.
Mohamad Kazempour, Hassan Namazi, Abolfazl Akbarzadeh, Roya Kabiri   +3 more
doaj   +1 more source

Click Chemistry of Melamine Dendrimers: Comparison of “Click-and-Grow” and “Grow-Then-Click” Strategies Using a Divergent Route to Diversity

Molecules, 2022
Dendrimers are attractive macromolecules for a broad range of applications owing to their well-defined shapes and dimensions, highly branched and globular architectures, and opportunities for exploiting multivalency.
Sanami Numai, Risako Yoto, Masataka Kimura, Eric E. Simanek, Yoshikazu Kitano   +4 more
doaj   +1 more source

Anti-prion drug mPPIg5 inhibits PrP(C) conversion to PrP(Sc). [PDF]

, 2013
Prion diseases, also known as transmissible spongiform encephalopathies, are a group of fatal neurodegenerative diseases that include scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle and Creutzfeldt-Jakob disease (CJD) in humans.
Jeremy C. Simpson (29225), Franke, Markus, Sibeal Waldron (277507), Appelhans Dietmar, Rogers Mark S., Dietmar Appelhans (277509), Resenberger, Ulrike K., Simpson Jeremy C., Simpson, Jeremy C., Jörg Tatzelt, Franke Markus, Resenberger Ulrike K., Rogers, Mark S., McCarthy James M., Mark S. Rogers (277510), James M McCarthy, Sibeal Waldron, Dietmar Appelhans, Appelhans, Dietmar, Mark S Rogers, Tatzelt Jörg, Tatzelt, Jörg, Ulrike K. Resenberger (277506), McCarthy, James M., Waldron, Sibeal, Markus Franke, Ulrike K Resenberger, Markus Franke (277505), Waldron Sibeal, Jeremy C Simpson, Jörg Tatzelt (277508), James M. McCarthy (277504)   +31 more
core   +1 more source

Which Dendrimer to Attain the Desired Properties? Focus on Phosphorhydrazone Dendrimers

Molecules, 2018
Among the six Critical Nanoscale Design Parameters (CNDPs) proposed by Prof. Donald A. Tomalia, this review illustrates the influence of the sixth one, which concerns the elemental composition, on the properties of dendrimers.
Anne-Marie Caminade, Jean-Pierre Majoral
doaj   +1 more source

Polyamidoamine (PAMAM) dendrimers synthesis, characterization and adsorptive removal of nickel ions from aqueous solution

Journal of Materials Research and Technology, 2020
Nickel is a toxic metal and present in the effluents of electroplating industries. Conventional methods to remove nickel are expensive and ineffective. Heavy metals can be easily adsorbed by dendrimers.
Isra Sohail, Ijaz Ahmad Bhatti, Ambreen Ashar, Fazli Malik Sarim, Muhammad Mohsin, Rizwana Naveed, Muhammad Yasir, Munawar Iqbal, Arif Nazir   +8 more
doaj   +1 more source

Application of Dendrimers in Anticancer Diagnostics and Therapy

Molecules, 2022
The application of dendrimeric constructs in medical diagnostics and therapeutics is increasing. Dendrimers have attracted attention due to their compact, spherical three-dimensional structures with surfaces that can be modified by the attachment of ...
Zuzanna Bober, Dorota Bartusik-Aebisher, David Aebisher   +2 more
doaj   +1 more source

Dendrimer Prodrugs [PDF]

Molecules, 2016
The main objective of this review is to describe the importance of dendrimer prodrugs in the design of new drugs, presenting numerous applications of these nanocomposites in the pharmaceutical field. Therefore, the use of dendrimer prodrugs as carrier for drug delivery, to improve pharmacokinetic properties of prototype, to promote drug sustained ...
Soraya da Silva Santos, Elizabeth Igne Ferreira, Jeanine Giarolla   +2 more
openaire   +3 more sources

Lipophilic Peptide Dendrimers for Delivery of Splice-Switching Oligonucleotides [PDF]

, 2021
Non-viral transfection reagents are continuously being developed in attempt to replace viral vectors. Among those non-viral vectors, dendrimers have gained increasing interest due to their unique molecular structure and multivalency.
Safa Bazaz, Bazaz, Safa, Marc Heitz, Karin E. Lundin, Reymond, Jean-Louis, Smith, C. I. Edvard, Darbre, Tamis, Osama Saher, Saher, Osama, EL Andaloussi, Samir, Jeremy P. Bost, Heitz, Marc, C. I. Edvard Smith, Susanna Zamolo, Jean-Louis Reymond, Zamolo, Susanna, P. Bost, Jeremy, Lundin, Karin E., Daralnakhla, Haneen, Tamis Darbre, Haneen Daralnakhla, Rula Zain, Samir EL Andaloussi, Zain, Rula   +23 more
core   +1 more source

T Cell-Association of Carboxy-Terminal Dendrimers with Different Bound Numbers of Phenylalanine and Their Application to Drug Delivery

Pharmaceutics, 2023
T cells play important roles in various immune reactions, and their activation is necessary for cancer immunotherapy. Previously, we showed that polyamidoamine (PAMAM) dendrimers modified with 1,2-cyclohexanedicarboxylic acid (CHex) and phenylalanine ...
Hiroya Shiba, Tomoka Hirose, Yunshen Fu, Masataka Michigami, Ikuo Fujii, Ikuhiko Nakase, Akikazu Matsumoto, Chie Kojima   +7 more
doaj   +1 more source