Results 21 to 30 of about 34,954 (198)

Click Chemistry of Melamine Dendrimers: Comparison of “Click-and-Grow” and “Grow-Then-Click” Strategies Using a Divergent Route to Diversity

Molecules, 2022
Dendrimers are attractive macromolecules for a broad range of applications owing to their well-defined shapes and dimensions, highly branched and globular architectures, and opportunities for exploiting multivalency.
Sanami Numai, Risako Yoto, Masataka Kimura, Eric E. Simanek, Yoshikazu Kitano   +4 more
doaj   +1 more source

Which Dendrimer to Attain the Desired Properties? Focus on Phosphorhydrazone Dendrimers

Molecules, 2018
Among the six Critical Nanoscale Design Parameters (CNDPs) proposed by Prof. Donald A. Tomalia, this review illustrates the influence of the sixth one, which concerns the elemental composition, on the properties of dendrimers.
Anne-Marie Caminade, Jean-Pierre Majoral
doaj   +1 more source

Cytotoxicity of Dendrimers [PDF]

Biomolecules, 2019
Drug delivery systems are molecular platforms in which an active compound is packed into or loaded on a biocompatible nanoparticle. Such a solution improves the activity of the applied drug or decreases its side effects. Dendrimers are promising molecular platforms for drug delivery due to their unique properties.
Anna Janaszewska, Joanna Lazniewska, Przemysław Trzepiński, Monika Marcinkowska, Barbara Klajnert-Maculewicz   +4 more
openaire   +3 more sources

T Cell-Association of Carboxy-Terminal Dendrimers with Different Bound Numbers of Phenylalanine and Their Application to Drug Delivery

Pharmaceutics, 2023
T cells play important roles in various immune reactions, and their activation is necessary for cancer immunotherapy. Previously, we showed that polyamidoamine (PAMAM) dendrimers modified with 1,2-cyclohexanedicarboxylic acid (CHex) and phenylalanine ...
Hiroya Shiba, Tomoka Hirose, Yunshen Fu, Masataka Michigami, Ikuo Fujii, Ikuhiko Nakase, Akikazu Matsumoto, Chie Kojima   +7 more
doaj   +1 more source

Dendrimer light-emitting diodes [PDF]

, 2008
The electronics industry today is one that stands as a multi-billion dollar industry that is increasingly incorporating more and more products that have ever escalating applications in our everyday life.
Stevenson, Stuart G.
core   +2 more sources

Polyamidoamine (PAMAM) dendrimers synthesis, characterization and adsorptive removal of nickel ions from aqueous solution

Journal of Materials Research and Technology, 2020
Nickel is a toxic metal and present in the effluents of electroplating industries. Conventional methods to remove nickel are expensive and ineffective. Heavy metals can be easily adsorbed by dendrimers.
Isra Sohail, Ijaz Ahmad Bhatti, Ambreen Ashar, Fazli Malik Sarim, Muhammad Mohsin, Rizwana Naveed, Muhammad Yasir, Munawar Iqbal, Arif Nazir   +8 more
doaj   +1 more source

Analysis of Biotinylated Generation 4 Poly(amidoamine) (PAMAM) Dendrimer Distribution in the Rat Brain and Toxicity in a Cellular Model of the Blood-Brain Barrier

Molecules, 2013
Dendrimers are highly customizable nanopolymers with qualities that make them ideal for drug delivery. The high binding affinity of biotin/avidin provides a useful approach to fluorescently label synthesized dendrimer-conjugates in cells and tissues.
Heather A. Bullen, Kristi L. Haik, Celeste Morris, Steven Wall, Anthony Haskamp, Megan Caroway, Michael Hester, Robert Spaulding, Brett Rossow, Ruth Hemmer, Andrew Hall   +10 more
doaj   +1 more source

Nanoparticle Effects on Human Platelets in Vitro: A Comparison between PAMAM and Triazine Dendrimers

Molecules, 2016
Triazine and PAMAM dendrimers of similar size and number of cationic surface groups were compared for their ability to promote platelet aggregation. Triazine dendrimers (G3, G5 and G7) varied in molecular weight from 8 kDa–130 kDa and in surface groups ...
Alan E. Enciso, Barry Neun, Jamie Rodriguez, Amalendu P. Ranjan, Marina A. Dobrovolskaia, Eric E. Simanek   +5 more
doaj   +1 more source

Anti-prion drug mPPIg5 inhibits PrP(C) conversion to PrP(Sc). [PDF]

, 2013
Prion diseases, also known as transmissible spongiform encephalopathies, are a group of fatal neurodegenerative diseases that include scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle and Creutzfeldt-Jakob disease (CJD) in humans.
Jeremy C. Simpson (29225), Franke, Markus, Sibeal Waldron (277507), Appelhans Dietmar, Rogers Mark S., Dietmar Appelhans (277509), Resenberger, Ulrike K., Simpson Jeremy C., Simpson, Jeremy C., Jörg Tatzelt, Franke Markus, Resenberger Ulrike K., Rogers, Mark S., McCarthy James M., Mark S. Rogers (277510), James M McCarthy, Sibeal Waldron, Dietmar Appelhans, Appelhans, Dietmar, Mark S Rogers, Tatzelt Jörg, Tatzelt, Jörg, Ulrike K. Resenberger (277506), McCarthy, James M., Waldron, Sibeal, Markus Franke, Ulrike K Resenberger, Markus Franke (277505), Waldron Sibeal, Jeremy C Simpson, Jörg Tatzelt (277508), James M. McCarthy (277504)   +31 more
core   +2 more sources

Nucleic Acid Carriers Based on Precise Polymer Conjugates [PDF]

, 2011
Polymer polydispersity, random conjugation of functional groups, and poorly understood structure–activity relationships have constantly hampered progress in the development of nucleic acid carriers.
Christina Troiber, Troiber, Christina, Wagner, Ernst, Ernst Wagner   +3 more
core   +1 more source