Results 91 to 100 of about 274,434 (381)
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
Of microtubules and memory: implications for microtubule dynamics in dendrites and spines
Molecular Biology of the Cell, 2017 Microtubules (MTs) are cytoskeletal polymers composed of repeating subunits of tubulin that are ubiquitously expressed in eukaryotic cells. They undergo a stochastic process of polymerization and depolymerization from their plus ends termed dynamic ...
E. Dent
semanticscholar +1 more source
Contrasting roles of axonal (pyramidal cell) and dendritic (interneuron) electrical coupling in the generation of neuronal network oscillations [PDF]
, 2003 Electrical coupling between pyramidal cell axons, and between interneuron dendrites, have both been described in the hippocampus. What are the functional roles of the two types of coupling?
Bibbig, A. +7 more
core +2 more sources
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
Journal of Neuroscience, 2016 In cultured vertebrate neurons, axons have a uniform arrangement of microtubules with plus-ends distal to the cell body (plus-end-out), whereas dendrites contain mixed polarity orientations with both plus-end-out and minus-end-out oriented microtubules ...
K. Yau +6 more
semanticscholar +1 more source
Effect of V and N on the microstructure evolution during continuous casting of steel [PDF]
, 2012 Low Carbon (LC) steel is not expected to be sensitive to hot tearing and/or cracking while microalloyed steels are known for their high cracking sensitivity during continuous casting. Experience of the Direct Sheet Plant caster at Tata Steel in Ijmuiden (
B Santillana +7 more
core +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
FEBS Open Bio, EarlyView.Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source
Ergodic Theory and Dynamical Systems, 2017 In this paper we develop a generalization of foliated manifolds in the context of metric spaces. In particular we study dendritations of surfaces that are defined as maximal atlases of compatible upper semicontinuous local decompositions into dendrites. Applications are given in modeling stable and unstable sets of topological dynamical systems.
openaire +3 more sources
Frontiers in Molecular Neuroscience, 2017 There have been several attempts to identify which RNAs are localized to dendrites; however, no study has determined which RNAs localize to the dendrites following the induction of synaptic activity.
Christopher A. de Solis +4 more
doaj +1 more source
eLife, 2020 Establishing appropriate sizes and shapes of dendritic arbors is critical for proper wiring of the central nervous system. Here we report that Insulin-like Peptide 2 (DILP2) locally activates transiently expressed insulin receptors in the central ...
Jiangnan Luo +6 more
doaj +1 more source