The FTLD risk factor TMEM106B controls lysosomal trafficking and dendrite outgrowth
Benjamin M. Schwenk
openalex +2 more sources
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni +13 more
wiley +1 more source
Diurnal Variation, Topographical Distribution and Day-to-Day Repeatability of Ocular Surface Epithelial Immune Cells in Individuals with Dry Eye Disease. [PDF]
Sadhu S +3 more
europepmc +1 more source
The Determination of Dendrite Coherency Point Characteristics Using Three New Methods for Aluminum Alloys [PDF]
Iban Vicario +4 more
openalex +1 more source
Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
Kinetochore proteins control microtubule dynamics in postmitotic neurons to regulate the formation of dendritic spines. [PDF]
Zhao G +13 more
europepmc +1 more source
CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura +4 more
wiley +1 more source
Dendritic compartment-specific spine formation in layer 5 neurons underlies cortical circuit maturation during adolescence. [PDF]
Egashira R +8 more
europepmc +1 more source

