Results 71 to 80 of about 284,053 (380)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
THERMODYNAMICS AND NANOSTRUCTURAL MECHANISMS OF PROCESSES OF MELTING AND CRYSTALLIZATION OF METALS
Литьë и металлургия, 2016 Melting and crystallization of metals are equilibrium thermodynamic processes. As the main structural units of dendrites serve construction nanocrystals which are formed of elementary nanocrystals.
V. Yu. Stetsenko
doaj
Generation of directional selectivity by individual thin dendrites in neocortical pyramidal neurons [PDF]
, 2010 Patterned 2-photon glutamate uncaging and local GABA iontophoresis were used to test, in brain slices, whether basal and oblique dendrites possess the biophysical machinery to contribute to the directional selectivity exhibited by many sensory ...
Guy Major
core +1 more source
Activity-dependent trafficking of lysosomes in dendrites and dendritic spines
Journal of Cell Biology, 2017 In neurons, lysosomes, which degrade membrane and cytoplasmic components, are thought to primarily reside in somatic and axonal compartments, but there is little understanding of their distribution and function in dendrites.
Marisa S Goo +7 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Primary and secondary dendrite spacing of Ni-based superalloy single crystals [PDF]
Journal of the Serbian Chemical Society, 2009 Ni-based superalloy single crystals were grown by different methods (gradient method and Bridgman technique with spontaneous nucleation and with seed).
SLOBODANKA KOSTIC +2 more
doaj +3 more sources
Effect of V and N on the microstructure evolution during continuous casting of steel [PDF]
, 2012 Low Carbon (LC) steel is not expected to be sensitive to hot tearing and/or cracking while microalloyed steels are known for their high cracking sensitivity during continuous casting. Experience of the Direct Sheet Plant caster at Tata Steel in Ijmuiden (
B Santillana +7 more
core +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Protein synthesis at synaptic sites on dendrites [PDF]
, 2001 Studies over the past 20 years have revealed that gene expression in neurons is carried out by a distributed network of translational machinery. One component of this network is localized in dendrites, where polyribosomes and associated membranous ...
Schuman, Erin M., Steward, Oswald
core +1 more source
Patterning of dendritic territories by dendrite-dendrite and dendrite-substrate interactions
, 2014 Dendrites develop in highly complex environments and their interactions with neighboring neurons and the substrate are thought to be important for the establishment of their dendritic territories. Mechanisms required for the establishment of dendritic territories remain largely elusive.
openaire +2 more sources