Results 51 to 60 of about 101,462 (267)

NANOSTRUCTURAL PROCESSES OF MELTING, CRYSTALLIZATION AND MODIFYINGS OF METALS

open access: yesЛитьë и металлургия, 2015
It is shown that melting, crystallization and modifying of metals are difficult nanostructural processes. The nanocrystals and atoms of metals, the centers of crystallization of dendrites, surface-active elements, gases modifying elements, poorly soluble
V. Yu. Stetsenko
doaj  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

THERMODYNAMICS AND NANOSTRUCTURAL MECHANISMS OF PROCESSES OF MELTING AND CRYSTALLIZATION OF METALS

open access: yesЛитьë и металлургия, 2016
Melting and crystallization of metals are equilibrium thermodynamic processes. As the main structural units of dendrites serve construction nanocrystals which are formed of elementary nanocrystals.
V. Yu. Stetsenko
doaj  

Calcium Dynamics in Basal Dendrites of Layer 5A and 5B Pyramidal Neurons Is Tuned to the Cell-Type Specific Physiological Action Potential Discharge

open access: yesFrontiers in Cellular Neuroscience, 2017
Layer 5 (L5) is a major neocortical output layer containing L5A slender-tufted (L5A-st) and L5B thick-tufted (L5B-tt) pyramidal neurons. These neuron types differ in their in vivo firing patterns, connectivity and dendritic morphology amongst other ...
Patrik Krieger   +6 more
doaj   +1 more source

Morphometric characteristics of the neurons of the human subiculum proper [PDF]

open access: yesArchives of Biological Sciences, 2012
The human subiculum is a significant part of the hippocampal formation positioned between the hippocampus proper and the entorhinal and other cortices.
Živanović-Mačužić Ivana   +7 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Golgi Outpost Synthesis Impaired by Toxic Polyglutamine Proteins Contributes to Dendritic Pathology in Neurons

open access: yesCell Reports, 2017
Dendrite aberration is a common feature of neurodegenerative diseases caused by protein toxicity, but the underlying mechanisms remain largely elusive.
Chang Geon Chung   +18 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Analyzing Branch‐specific Dendritic Spikes Using an Ultrafast Laser Scalpel

open access: yesFrontiers in Physics, 2020
Dendritic spikes facilitate neuronal computation and they have been reported to occur in various regions of the dendritic tree of cortical neurons.
Michael L. Castañares   +3 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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