Results 121 to 130 of about 468,502 (266)

Ionizable Lipid‐Dependent Optimization of Steroid Lipid Nanoparticles With Tunable Immunomodulatory Properties

Advanced Materials, EarlyView.
A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte, Benjamin E. Nachod, Julia Baena, Jenna Muscat‐Rivera, Lesley Chaboub, Hannah C. Safford, Hannah C. Geisler, Hannah M. Yamagata, Melgious J. Y. Ang, Michael Kegel, Alexandre Poirier, Elaine R. Tong, Zhe Zhong, Qiangqiang Shi, Jinjin Wang, Elisa Battistini, Ye Zeng, Alex G. Hamilton, Kelsey L. Swingle, Drew Weissman, Jilian R. Melamed, Michael J. Mitchell   +21 more
wiley   +1 more source

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

Dendritic Cell-T Cell Crosstalk Mediated Cancer Immunotherapy. [PDF]

Exploration (Beijing)
Cai Y, Chen J, Li Y.
europepmc   +1 more source

Sustainable and Multifunctional Natural Macromolecular Polymers for Aqueous Zn Metal Batteries

Advanced Materials, EarlyView.
We comprehensively review the structure‐function relationships and regulatory mechanism of natural macromolecular polymers in stabilizing zinc anodes at the microscopic and mesoscopic scales. The interactions among polymer structures, optimization strategies, and regulatory mechanisms are discussed systematically summarizing recent related research ...
Yunuo Shi, Bo Jiang, Jingcheng Zhang, Xiaodong Shao, Peixun Xiong, Lutong Shan, Shengyang Huang, Mengfang Liang, Mengyao Chang, Fangyan Liu, Wenwu Li, Baoyu Xia, Wei Ji, Ho Seok Park   +13 more
wiley   +1 more source

Matrix Viscoelasticity Regulates Dendritic Cell Migration and Immune Priming. [PDF]

Adv Mater
Jung WH, Humann E, Price JM, Binenbaum Y, Haseki A, Iyer S, Mooney DJ.   +6 more
europepmc   +1 more source

Low Resistance Interphase Formation at the PEO‐LiTFSI|LGPS Interface in Lithium Solid‐State Batteries

Advanced Materials Interfaces, EarlyView.
Interfacial charge transfer and low‐resistance interphase formation between PEO‐based polymer and Li10GeP2S12 solid electrolytes are investigated using multi‐electrode impedance spectroscopy and advanced analytical techniques such as XPS and ToF‐SIMS.
Ujjawal Sigar, Timo Weintraut, Sebastian L. Benz, Semih Engün, Sascha Kremer, Anja Henss, Felix H. Richter   +6 more
wiley   +1 more source

1701 Curli amyloid/DNA complexes from bacterial biofilms break tolerance in murine lupus using T cell-independent and T cell-dependent modalities

Lupus Science and Medicine, 2021
Roberto Caricchio, Stefania Gallucci, Michael H Lee, Sarah A Tursi, Lauren K Nicastro, Çagla Tükel, Benjamin L Green   +6 more
doaj   +1 more source

Blastic plasmacytoid dendritic cell neoplasm following Langerhans cell histiocytosis. [PDF]

JAAD Case Rep
Goto M, Akatsuka T, Uchiyama E, Urabe H, Shibamiya A, Nakaseko C, Komuta M, Hayashi Y, Hamada T, Sugaya M.   +9 more
europepmc   +1 more source

Design of High‐Energy Anode for All‐Solid‐State Lithium Batteries–A Model with Borohydride‐Based Electrolytes

Advanced Materials Interfaces, EarlyView.
This study proposes a function‐sharing anode design to enable nonmetallic lithium insertion while maintaining intimate interfacial contact with the solid‐state electrolyte. A combination of lithium‐compatible and conformable borohydrides, highly conformable indium metal, less‐graphitized acetylene black, and a layer of highly graphitized massive ...
Keita Kurigami, Akihiro Ishii, Itaru Oikawa, Hitoshi Takamura   +3 more
wiley   +1 more source

RETREG1-Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis. [PDF]

Adv Sci (Weinh)
Yao RQ, Ren C, Zheng LY, Li JY, Wu WF, Li YX, Wang LX, Duan Y, Wang L, Liu SQ, He PY, Zhao PY, Tong S, Li ZX, Zhang T, Wu MY, Wei ST, Dong N, Wu Y, Zhang H, Zhu XM, Zhang ZC, Wu GS, Xia ZF, Du XH, Kang HJ, Zou Z, Tang DL, Yao YM.   +28 more
europepmc   +1 more source