Results 1 to 10 of about 523,028 (369)
Innate Functions of Dendritic Cell Subsets in Cardiac Allograft Tolerance [PDF]
Frontiers in Immunology, 2020 Survival rates after heart transplant have significantly improved over the last decade. Nevertheless, long-term allograft viability after 10 years remains poor and the sequelae of transplant-associated immunosuppression increases morbidity.
Samantha Schroth +4 more
doaj +4 more sources
Dendritic cell subsets and implications for cancer immunotherapy [PDF]
Frontiers in ImmunologyDendritic cells (DCs) play a central role in the orchestration of effective T cell responses against tumors. However, their functional behavior is context-dependent.
Michael Y. Chen +5 more
doaj +4 more sources
Characterization of human blood dendritic cell subsets [PDF]
Blood, 2002 Dendritic cells (DCs) are key antigen-presenting cells for stimulating immune responses and they are now being investigated in clinical settings. Although defined as lineage-negative (Lin−) HLA-DR+ cells, significant heterogeneity in these preparations is apparent, particularly in regard to the inclusion or exclusion of CD14+, CD16+, and CD2+ cells ...
Kelli P. A. MacDonald +5 more
semanticscholar +4 more sources
Human Dendritic Cell Subsets, Ontogeny, and Impact on HIV Infection [PDF]
Frontiers in Immunology, 2019 Dendritic cells (DCs) play important roles in orchestrating host immunity against invading pathogens, representing one of the first responders to infection by mucosal invaders.
Jake William Rhodes +6 more
doaj +3 more sources
Dendritic cell subsets in cancer immunity and tumor antigen sensing. [PDF]
Cell Mol Immunol, 2023 Dendritic cells (DCs) exhibit a specialized antigen-presenting function and play crucial roles in both innate and adaptive immune responses. Due to their ability to cross-present tumor cell-associated antigens to naïve T cells, DCs are instrumental in ...
Del Prete A +6 more
europepmc +2 more sources
Human dendritic cell subsets: an update [PDF]
Immunology, 2018 Dendritic cells (DC) are a class of bone‐marrow‐derived cells arising from lympho‐myeloid haematopoiesis that form an essential interface between the innate sensing of pathogens and the activation of adaptive immunity.
M. Collin, V. Bigley
semanticscholar +4 more sources
Contrariety of Human Bone Marrow Mesenchymal Stromal Cell Functionality in Modulating Circulatory Myeloid and Plasmacytoid Dendritic Cell Subsets [PDF]
Biology, 2023 Mesenchymal Stromal Cells (MSCs) derived from bone marrow are widely tested in clinical trials as a cellular therapy for potential inflammatory disorders. The mechanism of action of MSCs in mediating immune modulation is of wide interest.
Crystal C. Uwazie +6 more
doaj +2 more sources
Functional Role of Dendritic Cell Subsets in Cancer Progression and Clinical Implications. [PDF]
Int J Mol Sci, 2020 Dendritic cells (DCs) constitute a complex network of cell subsets with common functions but also with many divergent aspects. All dendritic cell subsets share the ability to prime T cell response and to undergo a complex trafficking program related to ...
Del Prete A +9 more
europepmc +2 more sources
Decoding the Heterogeneity of Human Dendritic Cell Subsets. [PDF]
Trends in Immunology, 2020 Dendritic cells (DCs) have been classified into distinct subsets based on phenotype and ontogeny. In the past few years, high throughput single-cell approaches have revealed further heterogeneity of human DCs, in particular at the transcriptomic level. Herein examined, are recent studies describing new human DC populations based on single-cell RNA-seq ...
Javiera Villar, É. Segura
semanticscholar +3 more sources
Regulation of the Migration of Distinct Dendritic Cell Subsets [PDF]
Frontiers in Cell and Developmental Biology, 2021 Dendritic cells (DCs), a class of antigen-presenting cells, are widely present in tissues and apparatuses of the body, and their ability to migrate is key for the initiation of immune activation and tolerogenic immune responses.
Meng Feng +5 more
doaj +2 more sources