Results 111 to 120 of about 523,028 (369)
Grain Boundary Space Charge Engineering of Solid Oxide Electrolytes: Model Thin Film Study
Advanced Functional Materials, EarlyView.This study demonstrates unprecedented control of grain boundary electrical properties in solid electrolytes. Selective diffusion of cations through grain boundaries in thin films enables 12 orders of magnitude variation in ionic resistance, proving that systematic chemical modification of grain boundary electrical properties is feasible.
Thomas Defferriere +5 more
wiley +1 more source
IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection [PDF]
, 2016 Funding: This work was funded by a Career Development Fellowship (1028634) and a project grant (GRNT1028641) awarded to AHa by the Australian National Health & Medical Research Council (NHMRC).
A Haque +89 more
core +5 more sources
Molecular Mechanisms of Induction of Tolerant and Tolerogenic Intestinal Dendritic Cells in Mice
Journal of Immunology Research, 2016 How does the host manage to tolerate its own intestinal microbiota? A simple question leading to complicated answers. In order to maintain balanced immune responses in the intestine, the host immune system must tolerate commensal bacteria in the gut ...
Alex Steimle, Julia-Stefanie Frick
doaj +1 more source
Frontiers in Immunology, 2018 Dendritic cell (DC) based cancer immunotherapy aims at the activation of the immune system, and in particular tumor-specific cytotoxic T lymphocytes (CTLs) to eradicate the tumor. DCs represent a heterogeneous cell population, including conventional DCs (
A. Huber +3 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo +7 more
wiley +1 more source
Dendritic cell subsets in type 1 diabetes: friend or foe?
Frontiers in Immunology, 2013 Type 1 diabetes (T1D) is a T cell mediated autoimmune disease characterized by immune mediated destruction of the insulin producing β cells in the islets of Langerhans.
Penelope Anne Morel
doaj +1 more source
Advanced Functional Materials, EarlyView.The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang +13 more
wiley +1 more source
Evaluation of the effect of GM-CSF blocking on the phenotype and function of human monocytes [PDF]
, 2020 Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a multipotent cytokine that prompts the proliferation of bone marrow-derived macrophages and granulocytes.
Esmaeil, Nafiseh +3 more
core +2 more sources
Cross-Presentation of Cell-Associated Antigens by MHC Class I in Dendritic Cell Subsets
Frontiers in Immunology, 2015 Dendritic cells (DCs) have the unique ability to pick up dead cells carrying antigens in tissue and migrate to the lymph nodes where they can cross-present cell-associated antigens by MHC class I to CD8+ T cells. There is strong in vivo evidence that the
Enric Gutiérrez-Martínez +7 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava +7 more
wiley +1 more source