Results 41 to 50 of about 523,028 (369)

In Vitro and In Vivo Effects of Ketamine on Generation and Function of Dendritic Cells

Journal of Pharmacological Sciences, 2011
.: The question about how intravenous anesthetic reagents affect the development and function of dendritic cell subsets still has no comprehensive answers.
Jingxian Zeng, Shuxuan Xia, Wa Zhong, Jie Li, Liling Lin   +4 more
doaj   +1 more source

Antigen presenting capacity of murine splenic myeloid cells [PDF]

, 2017
BACKGROUND: The spleen is an important site for hematopoiesis. It supports development of myeloid cells from bone marrow-derived precursors entering from blood. Myeloid subsets in spleen are not well characterised although dendritic cell (DC) subsets are
Hey, Ying-Ying, O'Neill, Helen C, Quah, Benjamin   +2 more
core   +2 more sources

Human plasmacytoid dendritic cells and cutaneous melanoma [PDF]

, 2020
The prognosis of metastatic melanoma (MM) patients has remained poor for a long time. However, the recent introduction of effective target therapies (BRAF and MEK inhibitors for BRAFV600-mutated MM) and immunotherapies (anti-CTLA-4 and anti-PD-1) has ...
Bugatti, Mattia, Consoli, Francesca, Monti, Matilde, Vermi, William, Vescovi, Raffaella   +4 more
core   +2 more sources

pH-Degradable mannosylated nanogels for dendritic cell targeting [PDF]

, 2016
We report on the design of glycosylated nanogels via core-cross linking of amphiphilic non-water-soluble block copolymers composed of an acetylated glycosylated block and a pentafluorophenyl (PFP) activated ester block prepared by reversible addition ...
Ayres, Neil, De Coen, Ruben, De Geest, Bruno, De Koker, Stefaan, Grooten, Johan, Louage, Benoit, Lybaert, Lien, Nuhn, Lutz, Risseeuw, Martijn, Taylor, Leeanne, Udhayakumar, Vimal Kumar, Van Calenbergh, Serge, Vanparijs, Nane   +12 more
core   +2 more sources

Cross-organ single-cell transcriptome profiling reveals macrophage and dendritic cell heterogeneity in zebrafish

Cell Reports, 2023
Summary: Tissue-resident macrophages (TRMs) and dendritic cells (DCs) are highly heterogeneous and essential for immunity, tissue regeneration, and homeostasis maintenance.
Qiuxia Zhou, Changlong Zhao, Zhiyong Yang, Rui Qu, Yunbo Li, Yining Fan, Jinlin Tang, Ting Xie, Zilong Wen   +8 more
doaj   +1 more source

Phenotypic and functional heterogeneity of macrophages and dendritic cell subsets in the healthy and atherosclerosis-prone aorta.

Frontiers in Physiology, 2012
Atherosclerosis continues to be the leading cause of cardiovascular disease. Development of atherosclerosis depends on chronic inflammation in the aorta and multiple immune cells are involved in this process.
Elena V Galkina, Matthew J Butcher
doaj   +1 more source

Harnessing human dendritic cell subsets for medicine [PDF]

Immunological Reviews, 2010
Summary:  Immunity results from a complex interplay between the antigen‐non‐specific innate immune system and the antigen‐specific adaptive immune system. The cells and molecules of the innate system employ non‐clonal recognition receptors including lectins, Toll‐like receptors, NOD‐like receptors, and helicases.
Hideki, Ueno, Nathalie, Schmitt, Eynav, Klechevsky, Alexander, Pedroza-Gonzalez, Toshimichi, Matsui, Gerard, Zurawski, SangKon, Oh, Joseph, Fay, Virginia, Pascual, Jacques, Banchereau, Karolina, Palucka   +10 more
openaire   +2 more sources

Immunogenicity of targeted lentivectors [PDF]

, 2014
To increase the safety and possibly efficacy of HIV-1 derived lentivectors (LVs) as an anti-cancer vaccine, we recently developed the Nanobody (Nb) display technology to target LVs to antigen presenting cells (APCs).
Adotévi, Bennett, Bevan, Bhardwaj, Bhardwaj, Bhardwaj, Blander, Bonehill, Bonehill, Breckpot, Breckpot, Breckpot, Charleston, Chuah, Collins, Collins, Collins, Collins, Cosset, Diebold, Donckier, Eggermont, Enk, Figdor, Gajewski, Garcia, Groettrup, Inaba, Kast, Lahoutte, Lévy, McCullough, Medzhitov, Melief, Mellman, Mortha, Moser, Moser, Munn, Naldini, Neyns, Noguiez-Hellin, Nussenzweig, Palena, Raes, Reis e Sousa, Reiser, Reiser, Richardson, Romani, Roncarolo, Sakuma, Schroyens, Semesyuk, Song, Storm, Thielemans, Thielemans, Thielemans, Thielemans, Torretta, Turk, Van Kooyk, Wang, Wang, Yamaguchi, Yewdell, Yu   +67 more
core   +3 more sources

Dendritic cell-based vaccination in cancer: therapeutic implications emerging from murine models

Frontiers in Immunology, 2015
Dendritic cells (DCs) play a pivotal role in the orchestration of immune responses, and are thus key targets in cancer vaccine design. Since the 2010 FDA approval of the first cancer DC-based vaccine (Sipuleucel T) there has been a surge of interest in ...
Soledad eMac Keon, Maria Sol eRuiz, Silvina eGazzaniga, Rosa eWainstok, Rosa eWainstok   +4 more
doaj   +1 more source

Differences in host immune populations between rhesus macaques and cynomolgus macaque subspecies in relation to susceptibility to Mycobacterium tuberculosis infection

Scientific Reports, 2021
Rhesus (Macaca mulatta) and cynomolgus (Macaca fasicularis) macaques of distinct genetic origin are understood to vary in susceptibility to Mycobacterium tuberculosis, and therefore differences in their immune systems may account for the differences in ...
Laura Sibley, Owen Daykin-Pont, Charlotte Sarfas, Jordan Pascoe, Andrew D. White, Sally Sharpe   +5 more
doaj   +1 more source