Results 61 to 70 of about 523,028 (369)
Diversification of dendritic cell subsets [PDF]
The term dendritic cell (DC) refers to a population of hematopoietic cells with critical roles in immunity, including immune activation in response to pathogen-elicited danger signals and immune tolerance. Aberrant DC activity is an important contributing factor in autoimmunity, while severe DC depletion accompanies certain immunodeficiency conditions.
Li, Haiyan S, Watowich, Stephanie S
openaire +2 more sources
Potential mechanism of action of J5 vaccine in protection against severe bovine coliform mastitis. [PDF]
Coliform mastitis is one of the most difficult diseases to treat in the modern dairy industry. Curative therapy with antibiotics remains only moderately effective and depends on the stage at which the disease is treated, The most successful strategies ...
Burvenich, Christian +2 more
core +3 more sources
Regulation of dendritic cell subsets by NKT cells
NKT cells expressing both invariant TCRs and NK cell receptors are an important regulatory cell subset active during initiation of innate immune responses. They are involved in a wide variety of immune responses, but the molecular details of their regulatory action are unknown. Transcriptional profiling has been used for analysis of NKT cell activation
Jack L, Strominger +2 more
openaire +2 more sources
Dendritic cell subsets in rheumatoid arthritis [PDF]
Distinct myeloid DC and lymphoid DC subsets have been described, which regulate the nature and magnitude of immune responses. Therefore DC function must be carefully regulated, otherwise inappropriate responses may result in such chronic inflammatory diseases as rheumatoid arthritis (RA). In this study the composition and activation state of DC subsets
Summers, K, O'Donnell, J, Rothwell, A
openaire +1 more source
Nutrition, diet and immunosenescence [PDF]
Ageing is characterized by immunosenescence and the progressive decline in immunity in association with an increased frequency of infections and chronic disease.
Agrawal +217 more
core +1 more source
Targeting dendritic cells in vivo for cancer therapy
Monoclonal antibodies that recognise cell surface molecules have been used deliver antigenic cargo to dendritic cells (DC) for induction of immune responses.
Irina eCaminschi +3 more
doaj +1 more source
Human Dendritic Cell Subsets Undergo Distinct Metabolic Reprogramming for Immune Response
Toll-like receptor (TLR) agonists induce metabolic reprogramming, which is required for immune activation. We have investigated mechanisms that regulate metabolic adaptation upon TLR-stimulation in human blood DC subsets, CD1c+ myeloid DCs (mDCs) and ...
F. Basit +3 more
semanticscholar +1 more source
Influenza and memory T cells : how to awake the force [PDF]
Annual influenza vaccination is an effective way to prevent human influenza. Current vaccines are mainly focused on eliciting a strain-matched humoral immune response, requiring yearly updates, and do not provide protection for all vaccinated individuals.
Glezen +12 more
core +3 more sources
Comparison of Human Neonatal and Adult Blood Leukocyte Subset Composition Phenotypes. [PDF]
The human peripheral leukocyte subset composition depends on genotype variation and pre-natal and post-natal environmental influence diversity. We quantified this composition in adults and neonates, and compared the median values and dispersal ranges of ...
Savit B Prabhu +20 more
doaj +1 more source
Emerging Roles of Cellular Metabolism in Regulating Dendritic Cell Subsets and Function
Dendritic cells (DCs) are the bridge between innate and T cell-dependent adaptive immunity and are promising therapeutic targets for cancer and immune-mediated disorders.
Xingrong Du, Nicole M. Chapman, H. Chi
semanticscholar +1 more source

