Results 221 to 230 of about 87,585 (230)
Some of the next articles are maybe not open access.
Dendritic spines and linear networks
Journal of Physiology-Paris, 2004The function of the cortical microcircuitry is still mysterious. Using a bottom-up analysis based on the biophysics and connectivity of cortical neurons, we propose the hypothesis that the neocortex is essentially a linear integrator of inputs. Dendritic spines would slow the neuron and contribute to linearize input summation.
Rochelle Urban, Rafael Yuste
openaire +3 more sources
Dendritic spines for neuroprotection: a hypothesis
Trends in Neurosciences, 1995Ever since their first description in neurons, dendritic spines could be visualized only in fixed tissue, using high-power light and electron microscopy. Recent studies have been able to measure the free intracellular Ca2+ concentration ([Ca2+]i) in dendritic spines of live neurons, and the results suggest that the spine is an independent cellular Ca2+
openaire +3 more sources
Dendritic spine plasticity in hippocampus
Neuroscience, 2002Most excitatory input in the hippocampus and cerebral cortex impinges on dendritic spines. Alterations in dendritic spine density or shape are suspected to be morphological manifestations of changes in physiology or behavior. The links between spine plasticity and physiological responses have probably been best studied in the hippocampus in the context
Steve A. Kay +2 more
openaire +3 more sources
The Spine Apparatus, Synaptopodin, and Dendritic Spine Plasticity
The Neuroscientist, 2010The spine apparatus (SA) is an essential component of mature dendritic spines of cortical and hippocampal neurons, yet its functions are still enigmatic. Synaptopodin (SP), an actin-binding protein, colocalizes with the SA. Hippocampal neurons in SP-knockout mice lack SA, and they express lower LTP. SP probably plays a role in synaptic plasticity, but
Eduard Korkotian +2 more
openaire +3 more sources